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Takeda Asset Purchase and Stock Purchase Agreements - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
May 23, 2022
Oct. 18, 2021
Oct. 31, 2021
Dec. 31, 2022
Dec. 31, 2021
Jun. 01, 2022
May 22, 2022
Business Acquisition [Line Items]              
Preferred stock, shares issued       1,000,000 0    
Preferred stock, value, issued       $ 22,342      
Research and development related to asset acquisition         $ 50,875    
Stock price       $ 3.26      
Issuance costs         173    
Dividends       $ 0      
Mandatory Conversion              
Business Acquisition [Line Items]              
Qualified financing amount for conversion of preferred stock   $ 40,000          
Maximum weighted average price per share   $ 40.80          
Qualified financing mandatory conversion maximum number of shares   857,843          
Series A Convertible Preferred Stock              
Business Acquisition [Line Items]              
Preferred stock, value, issued $ 22,300            
Difference in fair value of the consideration transferred $ 18,400            
Issuance costs         $ 200    
Redemption rights       0      
Issuance of fair value   $ 40,900          
Series A Convertible Preferred Stock | ASC 480-10-S99-3A              
Business Acquisition [Line Items]              
Preferred stock, value, issued             $ 40,900
Series A Convertible Preferred Stock | Level 3              
Business Acquisition [Line Items]              
Preferred stock, value, issued       $ 22,300      
Series A Convertible Preferred Stock | Preferred Stock Purchase Agreement              
Business Acquisition [Line Items]              
Shareholders approved issuance percentage more than issued and outstanding shares           20.00%  
Series A Convertible Preferred Stock | Preferred Stock Purchase Agreement | Maximum              
Business Acquisition [Line Items]              
Convertible Preferred Stock, initially convertible into approximately 857,843 shares of common stock 6,644,014            
Series A Convertible Preferred Stock | Mandatory Conversion              
Business Acquisition [Line Items]              
Maximum weighted average price per share   $ 40.80          
Convertible Preferred Stock, initially convertible into approximately 857,843 shares of common stock   857,843          
Number of trading days   30 days          
Series A Convertible Preferred Stock | Optional Conversion              
Business Acquisition [Line Items]              
Maximum weighted average price per share   $ 40.80          
Qualified financing mandatory conversion maximum number of shares   857,843          
Millennium | Takeda Asset Purchase Agreement              
Business Acquisition [Line Items]              
Upfront Payment Paid     $ 10,000        
Clinical development, regulatory and sales milestone payments     470,000        
Asset acquisition, total consideration transferred     50,900        
Asset acquisition, cash payment     $ 10,000        
Millennium | Series A Convertible Preferred Stock | Takeda Asset Purchase Agreement              
Business Acquisition [Line Items]              
Preferred stock, shares issued     1,000,000        
Asset acquisition, consideration transferred, estimated fair value of shares     $ 40,900        
Millennium | Series A Convertible Preferred Stock | Takeda Asset Purchase Agreement | Level 3              
Business Acquisition [Line Items]              
Preferred stock, value, issued     $ 40,900        
Millennium | Series A Preferred Stock | Preferred Stock Purchase Agreement              
Business Acquisition [Line Items]              
Preferred stock, shares issued   1,000,000          
Stock price   $ 40.80          
Convertible Preferred Stock, initially convertible into approximately 857,843 shares of common stock   857,843