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Organization - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
Mar. 31, 2023
Dec. 31, 2022
Dec. 31, 2020
Subsidiary Sale Of Stock [Line Items]      
Accumulated deficit $ (634,135) $ (574,826)  
Cash, and investments $ 373,400    
Underwritten Public Offering | Pre-funded Warrant      
Subsidiary Sale Of Stock [Line Items]      
Pre-funded warrant, exercise price     $ 0.01