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Organization - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
Apr. 01, 2022
Mar. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Subsidiary Sale Of Stock [Line Items]        
Proceeds from common stock issuance $ 218,000      
Accumulated deficit   $ (405,618) $ (353,724)  
Cash, and investments   $ 187,500    
Underwritten Public Offering | Pre-funded Warrant        
Subsidiary Sale Of Stock [Line Items]        
Pre-funded warrants to purchase an additional shares of common stock       1,334,332
Underwritten Public Offering | Common Stock        
Subsidiary Sale Of Stock [Line Items]        
Common stock, price per share       $ 0.01