The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109   58,353,746 1,554,856 SH   SOLE   1,554,856 0 0
89BIO INC COM 282559103   85,886,299 7,378,548 SH   SOLE   7,378,548 0 0
ACADIA PHARMACEUTICALS INC COM 004225108   255,704,034 13,829,315 SH   SOLE   13,829,315 0 0
ACELYRIN INC COM 00445A100   6,603,593 978,310 SH   SOLE   978,310 0 0
ADICET BIO INC COM 007002108   9,716,383 4,134,631 SH   SOLE   4,134,631 0 0
AKERO THERAPEUTICS INC COM 00973Y108   137,211,941 5,431,985 SH   SOLE   5,431,985 0 0
ALKERMES PLC SHS G01767105   163,889,360 6,054,280 SH   SOLE   6,054,280 0 0
ALLURION TECHNOLOGIES INC COM SHS 02008G102   6,050,987 3,457,707 SH   SOLE   3,457,707 0 0
APOGEE THERAPEUTICS INC COM 03770N101   163,971,422 2,467,591 SH   SOLE   2,467,591 0 0
ARGENX SE SPONSORED ADR 04016X101   262,688,015 667,195 SH   SOLE   667,195 0 0
ARVINAS INC COM 04335A105   136,137,188 3,297,897 SH   SOLE   3,297,897 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108   1,437,103 127,970 SH   SOLE   127,970 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104   148,607,645 8,798,558 SH   SOLE   8,798,558 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   203,401,264 7,970,269 SH   SOLE   7,970,269 0 0
AXSOME THERAPEUTICS INC COM 05464T104   358,515,784 4,492,679 SH   SOLE   4,492,679 0 0
BEYOND AIR INC COM 08862L103   2,096,387 1,204,820 SH   SOLE   1,204,820 0 0
BRUKER CORP COM 116794108   314,144,284 3,344,095 SH   SOLE   3,344,095 0 0
CARGO THERAPEUTICS INC COM 14179K101   83,379,016 3,735,619 SH   SOLE   3,735,619 0 0
CG ONCOLOGY INC COM 156944100   18,160,113 413,670 SH   SOLE   413,670 0 0
CUTERA INC COM 232109108   1,957,711 1,331,776 SH   SOLE   1,331,776 0 0
CYTOKINETICS INC COM NEW 23282W605   177,033,359 2,525,080 SH   SOLE   2,525,080 0 0
DIANTHUS THERAPEUTICS INC COM 252828108   20,000,010 666,667 SH   SOLE   666,667 0 0
DYNE THERAPEUTICS INC COM 26818M108   87,770,155 3,091,587 SH   SOLE   3,091,587 0 0
ESSA PHARMA INC COM NEW 29668H708   19,515,640 2,298,662 SH   SOLE   2,298,662 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   136,193,283 2,675,703 SH   SOLE   2,675,703 0 0
EXACT SCIENCES CORP COM 30063P105   6,560,700 95,000 SH   SOLE   95,000 0 0
EXAGEN INC COM 30068X103   2,392,317 1,504,602 SH   SOLE   1,504,602 0 0
FULCRUM THERAPEUTICS INC COM 359616109   55,185,825 5,845,956 SH   SOLE   5,845,956 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   35,467,195 3,327,129 SH   SOLE   3,327,129 0 0
GLAUKOS CORP COM 377322102   5,543,403 58,791 SH   SOLE   58,791 0 0
IMMATICS N.V SHS N44445109   105,100,000 10,000,000 SH   SOLE   10,000,000 0 0
IMMUNIC INC COM 4525EP101   6,029,386 4,567,717 SH   SOLE   4,567,717 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105   391,276,665 6,019,641 SH   SOLE   6,019,641 0 0
INSMED INC COM PAR $.01 457669307   50,600,380 1,865,108 SH   SOLE   1,865,108 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   39,509,910 99,000 SH   SOLE   99,000 0 0
JANUX THERAPEUTICS INC COM 47103J105   37,650,000 1,000,000 SH   SOLE   1,000,000 0 0
KYVERNA THERAPEUTICS INC COM 501976104   46,021,341 1,852,711 SH   SOLE   1,852,711 0 0
LARIMAR THERAPEUTICS INC COM 517125100   4,933,500 650,000 SH   SOLE   650,000 0 0
LENZ THERAPEUTICS INC COM 52635N103   19,279,476 863,389 SH   SOLE   863,389 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   106,027,431 397,047 SH   SOLE   397,047 0 0
MASIMO CORP COM 574795100   214,753,440 1,462,400 SH   SOLE   1,462,400 0 0
MERUS N V COM N5749R100   185,045,967 4,109,393 SH   SOLE   4,109,393 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   5,828,423 3,256,102 SH   SOLE   3,256,102 0 0
NATERA INC COM 632307104   237,185,322 2,593,323 SH   SOLE   2,593,323 0 0
NEUROGENE INC COM 64135M105   39,148,310 769,122 SH   SOLE   769,122 0 0
ORCHESTRA BIOMED HLDGS INC COM 68572M106   29,620,773 5,620,640 SH   SOLE   5,620,640 0 0
PENUMBRA INC COM 70975L107   150,844,684 675,888 SH   SOLE   675,888 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   153,777,820 5,315,514 SH   SOLE   5,315,514 0 0
PTC THERAPEUTICS INC COM 69366J200   215,963,287 7,423,970 SH   SOLE   7,423,970 0 0
RADNET INC COM 750491102   82,748,763 1,700,550 SH   SOLE   1,700,550 0 0
REGENXBIO INC COM 75901B107   7,374,500 350,000 SH   SOLE   350,000 0 0
ROCKET PHARMACEUTICALS INC *W EXP 09/02/202 77313F114   104,720 350,000 SH   SOLE   350,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   476,508,578 17,687,772 SH   SOLE   17,687,772 0 0
ROIVANT SCIENCES LTD SHS G76279101   15,328,037 1,454,273 SH   SOLE   1,454,273 0 0
SAGE THERAPEUTICS INC COM 78667J108   102,706,013 5,480,577 SH   SOLE   5,480,577 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104   5,415,377 999,147 SH   SOLE   999,147 0 0
SAB BIOTHERAPEUTICS INC COM NEW 78397T202   4,166,934 917,827 SH   SOLE   917,827 0 0
SHOCKWAVE MED INC COM 82489T104   94,004,171 288,684 SH   SOLE   288,684 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   84,688,586 2,232,760 SH   SOLE   2,232,760 0 0
STOKE THERAPEUTICS INC COM 86150R107   57,035,313 4,224,838 SH   SOLE   4,224,838 0 0
STRYKER CORPORATION COM 863667101   114,876,270 321,000 SH   SOLE   321,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   118,949,595 3,272,341 SH   SOLE   3,272,341 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   53,362,441 18,593,185 SH   SOLE   18,593,185 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   64,223,705 110,500 SH   SOLE   110,500 0 0
TOURMALINE BIO INC COM 89157D105   16,983,922 741,656 SH   SOLE   741,656 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   330,897,399 7,087,115 SH   SOLE   7,087,115 0 0
UROGEN PHARMA LTD COM M96088105   48,860,205 3,257,347 SH   SOLE   3,257,347 0 0
VERICEL CORP COM 92346J108   83,564,772 1,606,397 SH   SOLE   1,606,397 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   10,607,838 605,816 SH   SOLE   605,816 0 0