0001493152-24-019465.txt : 20240515 0001493152-24-019465.hdr.sgml : 20240515 20240515074338 ACCESSION NUMBER: 0001493152-24-019465 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20240331 FILED AS OF DATE: 20240515 DATE AS OF CHANGE: 20240515 EFFECTIVENESS DATE: 20240515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: RTW INVESTMENTS, LP CENTRAL INDEX KEY: 0001493215 ORGANIZATION NAME: IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16670 FILM NUMBER: 24947188 BUSINESS ADDRESS: STREET 1: 40 10TH AVENUE STREET 2: 7TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10014 BUSINESS PHONE: 646-597-6980 MAIL ADDRESS: STREET 1: 40 10TH AVENUE STREET 2: 7TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10014 FORMER COMPANY: FORMER CONFORMED NAME: RTW INVESTMENTS, LLC DATE OF NAME CHANGE: 20100602 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false true false 0001493215 XXXXXXXX 03-31-2024 03-31-2024 false RTW INVESTMENTS, LP

40 10TH AVENUE 7Th FLOOR NEW YORK NY 10014

13F HOLDINGS REPORT 028-16670 000153232 801-78183 N Roderick Wong 646-597-6980 /s/ Roderick Wong New York NY 05-15-2024 0 69 6774577416 INFORMATION TABLE 2 infotable.xml 10X GENOMICS INC CL A COM 88025U109 58353746 1554856 SH SOLE 1554856 0 0 89BIO INC COM 282559103 85886299 7378548 SH SOLE 7378548 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 255704034 13829315 SH SOLE 13829315 0 0 ACELYRIN INC COM 00445A100 6603593 978310 SH SOLE 978310 0 0 ADICET BIO INC COM 007002108 9716383 4134631 SH SOLE 4134631 0 0 AKERO THERAPEUTICS INC COM 00973Y108 137211941 5431985 SH SOLE 5431985 0 0 ALKERMES PLC SHS G01767105 163889360 6054280 SH SOLE 6054280 0 0 ALLURION TECHNOLOGIES INC COM SHS 02008G102 6050987 3457707 SH SOLE 3457707 0 0 APOGEE THERAPEUTICS INC COM 03770N101 163971422 2467591 SH SOLE 2467591 0 0 ARGENX SE SPONSORED ADR 04016X101 262688015 667195 SH SOLE 667195 0 0 ARVINAS INC COM 04335A105 136137188 3297897 SH SOLE 3297897 0 0 ARYA SCIENCES ACQU CORP IV CL A G31659108 1437103 127970 SH SOLE 127970 0 0 AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 148607645 8798558 SH SOLE 8798558 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 203401264 7970269 SH SOLE 7970269 0 0 AXSOME THERAPEUTICS INC COM 05464T104 358515784 4492679 SH SOLE 4492679 0 0 BEYOND AIR INC COM 08862L103 2096387 1204820 SH SOLE 1204820 0 0 BRUKER CORP COM 116794108 314144284 3344095 SH SOLE 3344095 0 0 CARGO THERAPEUTICS INC COM 14179K101 83379016 3735619 SH SOLE 3735619 0 0 CG ONCOLOGY INC COM 156944100 18160113 413670 SH SOLE 413670 0 0 CUTERA INC COM 232109108 1957711 1331776 SH SOLE 1331776 0 0 CYTOKINETICS INC COM NEW 23282W605 177033359 2525080 SH SOLE 2525080 0 0 DIANTHUS THERAPEUTICS INC COM 252828108 20000010 666667 SH SOLE 666667 0 0 DYNE THERAPEUTICS INC COM 26818M108 87770155 3091587 SH SOLE 3091587 0 0 ESSA PHARMA INC COM NEW 29668H708 19515640 2298662 SH SOLE 2298662 0 0 ESTABLISHMENT LABS HLDGS INC COM G31249108 136193283 2675703 SH SOLE 2675703 0 0 EXACT SCIENCES CORP COM 30063P105 6560700 95000 SH SOLE 95000 0 0 EXAGEN INC COM 30068X103 2392317 1504602 SH SOLE 1504602 0 0 FULCRUM THERAPEUTICS INC COM 359616109 55185825 5845956 SH SOLE 5845956 0 0 GH RESEARCH PLC ORDINARY SHARES G3855L106 35467195 3327129 SH SOLE 3327129 0 0 GLAUKOS CORP COM 377322102 5543403 58791 SH SOLE 58791 0 0 IMMATICS N.V SHS N44445109 105100000 10000000 SH SOLE 10000000 0 0 IMMUNIC INC COM 4525EP101 6029386 4567717 SH SOLE 4567717 0 0 IMMUNOCORE HLDGS PLC ADS 45258D105 391276665 6019641 SH SOLE 6019641 0 0 INSMED INC COM PAR $.01 457669307 50600380 1865108 SH SOLE 1865108 0 0 INTUITIVE SURGICAL INC COM NEW 46120E602 39509910 99000 SH SOLE 99000 0 0 JANUX THERAPEUTICS INC COM 47103J105 37650000 1000000 SH SOLE 1000000 0 0 KYVERNA THERAPEUTICS INC COM 501976104 46021341 1852711 SH SOLE 1852711 0 0 LARIMAR THERAPEUTICS INC COM 517125100 4933500 650000 SH SOLE 650000 0 0 LENZ THERAPEUTICS INC COM 52635N103 19279476 863389 SH SOLE 863389 0 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 106027431 397047 SH SOLE 397047 0 0 MASIMO CORP COM 574795100 214753440 1462400 SH SOLE 1462400 0 0 MERUS N V COM N5749R100 185045967 4109393 SH SOLE 4109393 0 0 MILESTONE PHARMACEUTICALS IN COM 59935V107 5828423 3256102 SH SOLE 3256102 0 0 NATERA INC COM 632307104 237185322 2593323 SH SOLE 2593323 0 0 NEUROGENE INC COM 64135M105 39148310 769122 SH SOLE 769122 0 0 ORCHESTRA BIOMED HLDGS INC COM 68572M106 29620773 5620640 SH SOLE 5620640 0 0 PENUMBRA INC COM 70975L107 150844684 675888 SH SOLE 675888 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 153777820 5315514 SH SOLE 5315514 0 0 PTC THERAPEUTICS INC COM 69366J200 215963287 7423970 SH SOLE 7423970 0 0 RADNET INC COM 750491102 82748763 1700550 SH SOLE 1700550 0 0 REGENXBIO INC COM 75901B107 7374500 350000 SH SOLE 350000 0 0 ROCKET PHARMACEUTICALS INC *W EXP 09/02/202 77313F114 104720 350000 SH SOLE 350000 0 0 ROCKET PHARMACEUTICALS INC COM 77313F106 476508578 17687772 SH SOLE 17687772 0 0 ROIVANT SCIENCES LTD SHS G76279101 15328037 1454273 SH SOLE 1454273 0 0 SAGE THERAPEUTICS INC COM 78667J108 102706013 5480577 SH SOLE 5480577 0 0 SAGIMET BIOSCIENCES INC COM SER A 786700104 5415377 999147 SH SOLE 999147 0 0 SAB BIOTHERAPEUTICS INC COM NEW 78397T202 4166934 917827 SH SOLE 917827 0 0 SHOCKWAVE MED INC COM 82489T104 94004171 288684 SH SOLE 288684 0 0 SPYRE THERAPEUTICS INC COM NEW 00773J202 84688586 2232760 SH SOLE 2232760 0 0 STOKE THERAPEUTICS INC COM 86150R107 57035313 4224838 SH SOLE 4224838 0 0 STRYKER CORPORATION COM 863667101 114876270 321000 SH SOLE 321000 0 0 TARSUS PHARMACEUTICALS INC COM 87650L103 118949595 3272341 SH SOLE 3272341 0 0 TAYSHA GENE THERAPIES INC COM SHS 877619106 53362441 18593185 SH SOLE 18593185 0 0 THERMO FISHER SCIENTIFIC INC COM 883556102 64223705 110500 SH SOLE 110500 0 0 TOURMALINE BIO INC COM 89157D105 16983922 741656 SH SOLE 741656 0 0 ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 330897399 7087115 SH SOLE 7087115 0 0 UROGEN PHARMA LTD COM M96088105 48860205 3257347 SH SOLE 3257347 0 0 VERICEL CORP COM 92346J108 83564772 1606397 SH SOLE 1606397 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 10607838 605816 SH SOLE 605816 0 0