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Condensed Consolidated Statements of Series A Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Total
Series A Redeemable Convertible Preferred Stock [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Balance at Dec. 31, 2020 $ 8,726   $ 3 $ 431,689 $ (422,975) $ 9
Balance (in shares) at Dec. 31, 2020     2,961,579      
Stock-based compensation expense 1,308     1,308    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan 53     53    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan (in shares)     8,253      
Unrealized gain (loss) on marketable securities 7         7
Net loss (10,660)       (10,660)  
Balance at Mar. 31, 2021 (566)   $ 3 433,050 (433,635) 16
Balance (in shares) at Mar. 31, 2021     2,969,832      
Balance at Dec. 31, 2020 8,726   $ 3 431,689 (422,975) 9
Balance (in shares) at Dec. 31, 2020     2,961,579      
Net loss (37,097)          
Balance at Sep. 30, 2021 (2,463)   $ 3 457,602 (460,072) 4
Balance (in shares) at Sep. 30, 2021     3,319,355      
Balance at Mar. 31, 2021 (566)   $ 3 433,050 (433,635) 16
Balance (in shares) at Mar. 31, 2021     2,969,832      
Stock-based compensation expense 1,843     1,843    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan 251     251    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan (in shares)     9,253      
Issuance of common stock from secondary offering, net 19,968     19,968    
Issuance of common stock from secondary offering, net (in shares)     336,188      
Unrealized gain (loss) on marketable securities (12)         (12)
Net loss (12,475)       (12,475)  
Balance at Jun. 30, 2021 9,009   $ 3 455,112 (446,110) 4
Balance (in shares) at Jun. 30, 2021     3,315,273      
Stock-based compensation expense 2,466     2,466    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan 24     24    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan (in shares)     4,082      
Net loss (13,962)       (13,962)  
Balance at Sep. 30, 2021 (2,463)   $ 3 457,602 (460,072) 4
Balance (in shares) at Sep. 30, 2021     3,319,355      
Balance at Dec. 31, 2021 $ (12,903)   $ 3 459,314 (472,216) (4)
Balance (in shares) at Dec. 31, 2021 0          
Balance (in shares) at Dec. 31, 2021 3,328,017   3,328,017      
Stock-based compensation expense $ 2,552     2,552    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan (in shares)     40,028      
Surrender of shares due to tax withholding (231)     (231)    
Surrender of shares due to tax withholding (in shares)     (10,781)      
Issuance of common stock from secondary offering, net 1,433     1,433    
Issuance of common stock from secondary offering, net (in shares)     70,981      
Unrealized gain (loss) on marketable securities (7)         (7)
Net loss (16,495)       (16,495)  
Balance at Mar. 31, 2022 (25,651)   $ 3 463,068 (488,711) (11)
Balance (in shares) at Mar. 31, 2022     3,428,245      
Balance at Dec. 31, 2021 $ (12,903)   $ 3 459,314 (472,216) (4)
Balance (in shares) at Dec. 31, 2021 0          
Balance (in shares) at Dec. 31, 2021 3,328,017   3,328,017      
Net loss $ (51,904)          
Balance at Sep. 30, 2022 $ (31,669)   $ 7 492,444 (524,120)  
Balance (in shares) at Sep. 30, 2022 3,000 3,000        
Balance at Sep. 30, 2022 $ 330 $ 330        
Balance (in shares) at Sep. 30, 2022 7,050,849   7,050,849      
Balance at Mar. 31, 2022 $ (25,651)   $ 3 463,068 (488,711) (11)
Balance (in shares) at Mar. 31, 2022     3,428,245      
Stock-based compensation expense 1,534     1,534    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan 139     139    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan (in shares)     23,386      
Surrender of shares due to tax withholding (12)     (12)    
Issuance of common stock from secondary offering, net 4,494   $ 1 4,493    
Issuance of common stock from secondary offering, net (in shares)     517,352      
Unrealized gain (loss) on marketable securities 11         $ 11
Net loss (18,034)       (18,034)  
Balance at Jun. 30, 2022 (37,519)   $ 4 469,222 (506,745)  
Balance (in shares) at Jun. 30, 2022     3,968,983      
Stock-based compensation expense 1,372     1,372    
Issuance of common stock from vesting of restricted stock, exercise of stock options and employee stock purchase plan (in shares)     1,365      
Issuance of common stock from secondary offering, net 22,183   $ 3 22,180    
Issuance of common stock from secondary offering, net (in shares)     3,080,451      
Temporary equity stock issued during period (in shares)   3,000        
Deemed dividend on Series A redeemable convertible preferred stock (330)     (330)    
Temporary equity, deemed dividend   $ 330        
Misc adjustment to reflect rounding on reverse stock split     50      
Net loss (17,375)       (17,375)  
Balance at Sep. 30, 2022 $ (31,669)   $ 7 $ 492,444 $ (524,120)  
Balance (in shares) at Sep. 30, 2022 3,000 3,000        
Balance at Sep. 30, 2022 $ 330 $ 330        
Balance (in shares) at Sep. 30, 2022 7,050,849   7,050,849