Development Derivative Liability and Development Liability - Summary of Development Liability (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Less: Current portion of development liability, net of discount		$ (4,230)
Total long term development liability		253,638
SFJ Agreement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Development liability	$ 456,000
Less: Unamortized discount to development liability	(103,265)
Less: Current portion of development liability, net of discount	(7,584)	(4,200)
Total long term development liability	$ 345,151	$ 257,900
Effective Interest Rate	7.91%