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Consolidated Balance Sheets - USD ($)
Dec. 31, 2017
Dec. 31, 2016
Current assets:    
Cash and cash equivalents $ 175,643,529 $ 24,863,488
Refundable research and development credit 1,297,361 1,347,804
Prepaid assets 5,059,593 1,132,438
Other current assets 14,823 25,000
Total current assets 182,015,306 27,368,730
Other assets 116,150 64,528
Total assets 182,131,456 27,433,258
Current liabilities:    
Accounts payable 3,663,253 2,547,212
Accrued expenses 2,890,705 1,091,726
Total current liabilities 6,553,958 3,638,938
Long-term liabilities:    
Term loan facility 19,806,944  
Promissory note - related party 6,583,402  
Common stock warrant liability 244,292  
Total liabilities 33,188,596 3,638,938
Stockholders' equity:    
Preferred stock value
Common stock, $0.0001 par value; 87,000,000 shares authorized and 8,428,366 shares issued and outstanding at December 31, 2016 and 200,000,000 shares authorized and 50,334,152 shares issued and outstanding at December 31, 2017 5,033 843
Additional paid in capital 298,201,480 29,996,110
Accumulated deficit (149,263,653) (98,257,559)
Total stockholders' equity 148,942,860 23,794,320
Total liabilities and stockholders' equity $ 182,131,456 27,433,258
Series A Convertible Preferred Stock [Member]    
Stockholders' equity:    
Preferred stock value   2,654,405
Series B Convertible Preferred Stock [Member]    
Stockholders' equity:    
Preferred stock value   6,944,148
Series C Convertible Preferred Stock [Member]    
Stockholders' equity:    
Preferred stock value   35,542,707
Series D Convertible Preferred Stock [Member]    
Stockholders' equity:    
Preferred stock value   $ 46,913,666