Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($) $ in Thousands	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Other Comprehensive Income/(Loss) [Member]	Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2022	$ 169,872	$ 11	$ 2,479,596	$ (875)	$ (2,308,860)
Beginning balance, Shares at Dec. 31, 2022		110,772,000
Issuance of common stock and pre-funded warrants in common stock offering	384,387	$ 1	384,386
Issuance of common stock and pre-funded warrants in common stock offering, shares		4,008,000
Issuance of common stock upon exercise of stock options	17,718		17,718
Issuance of common stock upon exercise of stock options, shares		951,000
Vesting of restricted stock units, net of shares withheld for taxes	(10,999)		(10,999)
Vesting of restricted stock units, net of shares withheld for taxes. shares		448,000
Share-based compensation expense	28,823		28,823
Net loss	(177,778)				(177,778)
Foreign currency translation	100			100
Ending balance at Mar. 31, 2023	412,123	$ 12	2,899,524	(775)	(2,486,638)
Ending balance, Shares at Mar. 31, 2023		116,179,000
Beginning balance at Dec. 31, 2022	169,872	$ 11	2,479,596	(875)	(2,308,860)
Beginning balance, Shares at Dec. 31, 2022		110,772,000
Net loss	(440,052)
Foreign currency translation	(190)
Ending balance at Sep. 30, 2023	232,271	$ 12	2,982,236	(1,065)	(2,748,912)
Ending balance, Shares at Sep. 30, 2023		118,359,000
Beginning balance at Mar. 31, 2023	412,123	$ 12	2,899,524	(775)	(2,486,638)
Beginning balance, Shares at Mar. 31, 2023		116,179,000
Issuance of common stock upon exercise of stock options	22,334		22,334
Issuance of common stock upon exercise of stock options, shares		1,208,000
Vesting of restricted stock units, net of shares withheld for taxes	(27)		(27)
Vesting of restricted stock units, net of shares withheld for taxes. shares		119,000
Share-based compensation expense	29,277		29,277
Issuance of common stock to employee stock purchase plan	3,754		3,754
Issuance of common stock to employee stock purchase plan, shares		73,000
Net loss	(122,037)				(122,037)
Foreign currency translation	(21)			(21)
Ending balance at Jun. 30, 2023	345,403	$ 12	2,954,862	(796)	(2,608,675)
Ending balance, Shares at Jun. 30, 2023		117,579,000
Issuance of common stock upon exercise of stock options	5,757		5,757
Issuance of common stock upon exercise of stock options, shares		665,000
Vesting of restricted stock units, net of shares withheld for taxes	(9)		(9)
Vesting of restricted stock units, net of shares withheld for taxes. shares		115,000
Share-based compensation expense	21,626		21,626
Net loss	(140,237)				(140,237)
Foreign currency translation	(269)			(269)
Ending balance at Sep. 30, 2023	232,271	$ 12	2,982,236	(1,065)	(2,748,912)
Ending balance, Shares at Sep. 30, 2023		118,359,000
Beginning balance at Dec. 31, 2023	194,521	$ 12	3,035,539	(3,542)	(2,837,488)
Beginning balance, Shares at Dec. 31, 2023		119,556,000
Proceeds from settlement of capped call	98,763		98,763
Issuance of common stock upon exercise of stock options	9,477		9,477
Issuance of common stock upon exercise of stock options, shares		714,000
Vesting of restricted stock units, net of shares withheld for taxes	(28)		(28)
Vesting of restricted stock units, net of shares withheld for taxes. shares		997,000
Share-based compensation expense	30,349		30,349
Net loss	(66,423)				(66,423)
Foreign currency translation	17			17
Ending balance at Mar. 31, 2024	266,676	$ 12	3,174,100	(3,525)	(2,903,911)
Ending balance, Shares at Mar. 31, 2024		121,267,000
Beginning balance at Dec. 31, 2023	194,521	$ 12	3,035,539	(3,542)	(2,837,488)
Beginning balance, Shares at Dec. 31, 2023		119,556,000
Proceeds from settlement of capped call	98,763
Net loss	(161,525)
Foreign currency translation	402
Ending balance at Sep. 30, 2024	237,121	$ 12	3,239,262	(3,140)	(2,999,013)
Ending balance, Shares at Sep. 30, 2024		122,069,000
Beginning balance at Mar. 31, 2024	266,676	$ 12	3,174,100	(3,525)	(2,903,911)
Beginning balance, Shares at Mar. 31, 2024		121,267,000
Issuance of common stock upon exercise of stock options	1,962		1,962
Issuance of common stock upon exercise of stock options, shares		233,000
Vesting of restricted stock units, net of shares withheld for taxes. shares		102,000
Share-based compensation expense	29,990		29,990
Issuance of common stock to employee stock purchase plan	3,193		3,193
Issuance of common stock to employee stock purchase plan, shares		85,000
Net loss	(37,657)				(37,657)
Foreign currency translation	163			163
Ending balance at Jun. 30, 2024	264,327	$ 12	3,209,245	(3,362)	(2,941,568)
Ending balance, Shares at Jun. 30, 2024		121,687,000
Issuance of common stock upon exercise of stock options	2,556		2,556
Issuance of common stock upon exercise of stock options, shares		112,000
Vesting of restricted stock units, net of shares withheld for taxes	(14)		(14)
Vesting of restricted stock units, net of shares withheld for taxes. shares		270,000
Share-based compensation expense	27,475		27,475
Net loss	(57,445)				(57,445)
Foreign currency translation	222			222
Ending balance at Sep. 30, 2024	$ 237,121	$ 12	$ 3,239,262	$ (3,140)	$ (2,999,013)
Ending balance, Shares at Sep. 30, 2024		122,069,000