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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Revenue:        
Revenue $ 196,830 $ 110,399 $ 568,839 $ 250,214
Operating expenses:        
Cost of sales 33,557 22,410 76,867 38,598
Research and development 88,569 79,421 251,216 285,105
Selling, general and administrative 121,984 145,648 379,571 359,114
Total operating expenses: 244,110 247,479 707,654 682,817
Net operating loss (47,280) (137,080) (138,815) (432,603)
Loss on extinguishment of development liability     (1,949)  
Interest income 2,889 4,989 9,377 16,385
Interest expense (12,532) (7,310) (28,857) (22,179)
Other income/(expense), net 70 (603) (405) (946)
Net loss before taxes (56,853) (140,004) (160,649) (439,343)
Income tax expense 592 233 876 709
Net loss (57,445) (140,237) (161,525) (440,052)
Other comprehensive gain/(loss):        
Foreign currency translation 222 (269) 402 (190)
Total other comprehensive income 222 (269) 402 (190)
Comprehensive loss, net of tax $ (57,223) $ (140,506) $ (161,123) $ (440,242)
Net loss per common share, basic $ (0.46) $ (1.17) $ (1.31) $ (3.73)
Net loss per common share, diluted $ (0.46) $ (1.17) $ (1.31) $ (3.73)
Weighted-average number of common shares used in net loss per common share, basic 124,234 120,292 123,698 117,827
Weighted-average number of common shares used in net loss per common share, diluted 124,234 120,292 123,698 117,827
Product Revenue, Net [Member]        
Revenue:        
Revenue $ 176,571 $ 99,182 $ 518,782 $ 227,626
Licensing and other revenue [Member]        
Revenue:        
Revenue $ 20,259 $ 11,217 $ 50,057 $ 22,588