Product Revenues, Accounts Receivable, and Reserves for Product Sales - Schedule of Disaggregation of Product Revenue by Major Source (Detail) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]
Total Product revenue, net	$ 199,685	$ 94,969	$ 372,009	$ 139,814
EMPAVELI [Member]
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]
Total Product revenue, net	24,512	22,303	50,122	42,742
SYFOVRE [Member]
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]
Total Product revenue, net	154,624	67,342	292,089	85,702
Product Revenue, Net [Member]
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]
Total Product revenue, net	$ 179,136	$ 89,645	$ 342,211	$ 128,444