Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands |
Dec. 31, 2023 |
Dec. 31, 2022 |
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Deferred tax assets: | ||
Intangible assets | $ 192,444 | $ 187,839 |
Share-based compensation | 31,712 | 29,673 |
Net operating loss carryforwards | 329,135 | 228,985 |
Research and development credits | 67,667 | 57,419 |
Orphan drug credits | 34,023 | 30,160 |
Development derivative liability | 75,190 | 79,374 |
Convertible debt | 5,582 | 6,850 |
Fixed Assets | 18 | |
Lease liability | 2,888 | 4,304 |
Accruals | 17,401 | 16,272 |
Total deferred tax assets | 756,060 | 640,876 |
Deferred tax liabilities: | ||
Fixed assets | (91) | |
Right-of-use asset | (2,672) | (4,032) |
481(a) adjustment | (233) | |
Total deferred tax liabilities | (2,672) | (4,356) |
Net deferred tax assets before allowance: | 753,388 | 636,520 |
Less valuation allowance | $ (753,388) | $ (636,520) |
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- Definition Deferred tax asset lease liability. No definition available.
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- Definition Deferred tax assets convertible debt. No definition available.
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- Definition Deferred tax assets orphan drug credits. No definition available.
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- Definition Deferred tax liability section 481 (a) adjustment. No definition available.
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- Definition Deferred tax liability right of use asset. No definition available.
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- Definition Net deferred tax assets before valuation allowance. No definition available.
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- Definition Amount of deferred tax liability attributable to taxable temporary differences. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from derivative instruments. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from intangible assets including goodwill. No definition available.
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- References No definition available.
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from property, plant, and equipment. No definition available.
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from reserves and accruals. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- References No definition available.
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- Definition Amount of deferred tax liability attributable to taxable temporary differences from property, plant, and equipment. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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