Accrued Expenses - Schedule of Accrued Expenses (Detail) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Payables and Accruals [Abstract]
Accrued research and development	$ 31,510	$ 34,849
Accrued royalties	1,558	907
Accrued payroll liabilities	24,189	43,212
Other	13,994	16,171
Total accrued expenses	$ 71,251	$ 95,139