Note 2 - Liquidity and Capital Resources	12 Months Ended
Dec. 31, 2020
Notes to Financial Statements
Liquidity and Capital Resources [Text Block]	NOTE 2: LIQUIDITY AND CAPITAL RESOURCES The Company has incurred net losses and negative operating cash flows since inception. For the year ended December 31, 2020, the Company recorded a net loss of approximately $17.8 million and used approximately $11.6 million of cash in operating activities. As of December 31, 2020, the Company had approximately $39.6 million in cash and cash equivalents and working capital of approximately $27.1 million. The Company has not yet established an ongoing source of revenue sufficient to cover its operating costs and believes it will need to continue to raise substantial additional capital to accomplish its business plan over the next several years. Management believes its currently available funding, including the funds received from warrant exercises and a financing transaction with gross proceeds of approximately $102.4 million in the first quarter of 2021, will be sufficient to finance the Company's operations for at least one year from the date these consolidated financial statements are issued. The Company plans to continue to fund its losses from operations and capital funding needs through a combination of public or private equity offerings, debt financings or other sources, including potential corporate collaborations, licenses and other similar arrangements. There can be no assurance as to the availability or terms upon which such financing and capital might be available in the future. If the Company is unable to secure additional funding, it may be forced to curtail or suspend its business plans.

NOTE

LIQUIDITY AND CAPITAL RESOURCES

The Company has incurred net losses and negative operating cash flows since inception. For the year ended

December

31,

2020,

the Company recorded a net loss of approximately

$17.8

million and used approximately

$11.6

million of cash in operating activities. As of

December 31, 2020,

the Company had approximately

$39.6

million in cash and cash equivalents and working capital of approximately

$27.1

million. The Company has

not

yet established an ongoing source of revenue sufficient to cover its operating costs and believes it will need to continue to raise substantial additional capital to accomplish its business plan over the next several years. Management believes its currently available funding, including the funds received from warrant exercises and a financing transaction with gross proceeds of approximately

$102.4

million in the

first

quarter of

2021,

will be sufficient to finance the Company's operations for at least

one

year from the date these consolidated financial statements are issued. The Company plans to continue to fund its losses from operations and capital funding needs through a combination of public or private equity offerings, debt financings or other sources, including potential corporate collaborations, licenses and other similar arrangements. There can be

assurance as to the availability or terms upon which such financing and capital might be available in the future. If the Company is unable to secure additional funding, it

may

be forced to curtail or suspend its business plans.