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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Deficit
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Beginning balance (in shares)   34,702,565    
Beginning balance (in shares)   43,105,466    
Beginning balance at Dec. 31, 2017 $ 18,034 $ 35 $ 170,330 $ (152,331)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Exercise of stock options and vesting of restricted stock awards (in shares)   4,430    
Exercise of stock options and vesting of restricted stock awards 0      
Issuance of common stock pursuant to the 2014 ESPP (in shares)   9,565    
Issuance of common stock pursuant to the 2014 ESPP 10   10  
Exercise of common stock warrants (in shares)   420,778    
Exercise of common stock warrants 336   336  
Issuance of common stock and common stock warrants, net of issuance costs (in shares)   7,968,128    
Issuance of common stock and common stock warrants, net of issuance costs 9,040 $ 8 9,032  
Stock-based compensation expense 401   401  
Net loss (3,963)     (3,963)
Ending balance (in shares) at Mar. 31, 2018   43,105,466    
Ending balance at Mar. 31, 2018 23,858 $ 43 180,109 (156,294)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Beginning balance (in shares)   77,010,999    
Beginning balance at Dec. 31, 2017 18,034 $ 35 170,330 (152,331)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Net loss (12,921)      
Ending balance (in shares) at Jun. 30, 2018   77,010,999    
Ending balance at Jun. 30, 2018 64,064 $ 77 229,239 (165,252)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Beginning balance (in shares)   43,105,466    
Beginning balance (in shares)   77,010,999    
Beginning balance at Mar. 31, 2018 23,858 $ 43 180,109 (156,294)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Exercise of stock options and vesting of restricted stock awards (in shares)   55,259    
Exercise of stock options and vesting of restricted stock awards 29   29  
Exercise of common stock warrants (in shares)   8,294,718    
Exercise of common stock warrants 6,918 $ 8 6,910  
Issuance of common stock and common stock warrants, net of issuance costs (in shares)   25,555,556    
Issuance of common stock and common stock warrants, net of issuance costs 41,932 $ 26 41,906  
Stock-based compensation expense 285   285  
Net loss (8,958)     (8,958)
Ending balance (in shares) at Jun. 30, 2018   77,010,999    
Ending balance at Jun. 30, 2018 64,064 $ 77 229,239 (165,252)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Beginning balance (in shares)   77,010,999    
Beginning balance (in shares)   77,456,180    
Beginning balance (in shares)   77,464,781    
Beginning balance at Dec. 31, 2018 44,207 $ 77 230,154 (186,024)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Issuance of common stock pursuant to the 2014 ESPP (in shares)   8,601    
Issuance of common stock pursuant to the 2014 ESPP 7   7  
Stock-based compensation expense 326   326  
Net loss (6,480)     (6,480)
Ending balance (in shares) at Mar. 31, 2019   77,464,781    
Ending balance at Mar. 31, 2019 38,060 $ 77 230,487 (192,504)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Beginning balance (in shares)   101,265,896    
Beginning balance at Dec. 31, 2018 $ 44,207 $ 77 230,154 (186,024)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Exercise of stock options and vesting of restricted stock awards (in shares) 30,000      
Exercise of common stock warrants (in shares) 3,361,115      
Net loss $ (60,815)      
Ending balance (in shares) at Jun. 30, 2019   101,265,896    
Ending balance at Jun. 30, 2019 15,369 $ 101 262,107 (246,839)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Beginning balance (in shares)   77,464,781    
Beginning balance (in shares)   101,265,896    
Beginning balance at Mar. 31, 2019 38,060 $ 77 230,487 (192,504)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Exercise of stock options and vesting of restricted stock awards (in shares)   30,000    
Exercise of stock options and vesting of restricted stock awards $ 45   45  
Exercise of common stock warrants (in shares) 3,400,000 3,361,115    
Exercise of common stock warrants $ 3,434 $ 4 3,430  
Issuance of common stock and common stock warrants, net of issuance costs (in shares)   20,410,000    
Issuance of common stock and common stock warrants, net of issuance costs 27,809 $ 20 27,789  
Stock-based compensation expense 356   356  
Net loss (54,335)     (54,335)
Ending balance (in shares) at Jun. 30, 2019   101,265,896    
Ending balance at Jun. 30, 2019 $ 15,369 $ 101 $ 262,107 $ (246,839)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Beginning balance (in shares)   101,265,896