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Accrued Expenses (Details) - USD ($)
Sep. 28, 2018
Mar. 31, 2019
Dec. 31, 2018
Deferred Compensation Arrangement with Individual, Postretirement Benefits [Line Items]      
Development costs   $ 3,542,000 $ 2,928,000
Employee compensation   491,000 1,045,000
Severance to former CEO and other employees   610,000 278,000
Professional fees   519,000 464,000
Other   72,000 31,000
Total accrued expenses   5,234,000 $ 4,746,000
Former President and Chief Executive Officer      
Deferred Compensation Arrangement with Individual, Postretirement Benefits [Line Items]      
Severance to former CEO and other employees $ 637,500 $ 158,000  
Base salary 425,000    
Bonuses $ 212,500    
Separation Agreement, health and dental insurance coverage period (up to) 12 months