CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Operating activities
Net (loss) income	$ (33,693)	$ (29,029)	$ 1,891
Adjustments to reconcile net (loss) income to net cash (used in) provided by operating activities:
Depreciation	208	285	178
Non-cash interest expense	0	0	26
Stock-based compensation expense	1,283	1,381	4,013
Change in fair value of warrant liability	0	(5)	(110)
Loss (gain) from change in fair value of contingent consideration	8,800	9,100	(1,100)
Loss on extinguishment of debt	0	0	221
Gain on sale of equipment	(5)	(108)	(24)
Changes in operating assets and liabilities:
Prepaid expenses and other assets	(913)	164	800
Accounts payable	460	(760)	(742)
Accrued expenses and other liabilities	1,031	1,746	(1,936)
Deferred revenue	0	(425)	19
Due to related party	0	(114)	(698)
Net cash (used in) provided by operating activities	(22,829)	(17,765)	2,538
Investing activities
Cash acquired in acquisition	0	0	136
Sales (purchases) of property and equipment	(2)	98	325
Net cash provided by (used in) investing activities	(2)	98	461
Financing activities
Payments on equipment financing and notes payable	0	0	(14,124)
Proceeds from issuance of common stock and common stock warrants, net of issuance costs	58,286	6,908	0
Proceeds from exercise of common stock options and common stock warrants	277	85	269
Proceeds from sale of common stock pursuant to ESPP	20	12	35
Net cash provided by (used in) financing activities	58,583	7,005	(13,820)
Net decrease in cash, cash equivalents and restricted cash	35,752	(10,662)	(10,821)
Cash, cash equivalents and restricted cash at beginning of period	14,690	25,352	36,173
Cash, cash equivalents and restricted cash at end of period	50,442	14,690	25,352
Supplemental non-cash investing and financing activities
Common stock issued in connection with the acquisition (Note 3)	0	0	13,525
Fair value of assets acquired in the acquisition, excluding cash	0	0	79,366
Fair value of liabilities assumed in the acquisition	0	0	19,777
Adjustment to fair value of assets acquired and liabilities assumed during provisional period (Note 3)	0	14,600	0
Issuance of warrants to purchase common stock	0	2,679	0
Supplemental cash flow information
Cash paid for interest	$ 0	$ 0	$ 663

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Amount of cash inflow from exercise of stock options granted under share-based compensation arrangement.

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2A
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=109197908&loc=SL79508275-113901

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 14
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3255-108585

+ Details

Name:	us-gaap_ProceedsFromStockOptionsExercised
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

The cash outflow for a borrowing supported by a written promise to pay an obligation.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 15
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3291-108585

+ Details

Name:	us-gaap_RepaymentsOfNotesPayable
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

The aggregate amount of noncash, equity-based employee remuneration. This may include the value of stock or unit options, amortization of restricted stock or units, and adjustment for officers' compensation. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method.

+ References

+ Details

Name:	us-gaap_ShareBasedCompensation
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

The fair value of stock issued in noncash financing activities.

+ References

+ Details

Name:	us-gaap_StockIssued1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- References

No definition available.

+ Details

Name:	us-gaap_SupplementalCashFlowInformationAbstract
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration