Commitments and Contingencies - Operating Leases (Details)	1 Months Ended		3 Months Ended	12 Months Ended		15 Months Ended
	Dec. 31, 2017 USD ($)	May 31, 2017 USD ($)	Dec. 31, 2016 USD ($) term	Dec. 31, 2018 USD ($) option	Dec. 31, 2017 USD ($)	Dec. 31, 2017 ft²	Jan. 01, 2019 USD ($)
Other Commitments [Line Items]
Rent expense recorded					$ 565,000
Subsequent Event | Minimum | ASU 2016-02 | Scenario, Forecast
Other Commitments [Line Items]
Right-of-use asset							$ 100,000
Lease, liability							100,000
Subsequent Event | Maximum | ASU 2016-02 | Scenario, Forecast
Other Commitments [Line Items]
Right-of-use asset							400,000
Lease, liability							$ 400,000
Canada
Other Commitments [Line Items]
Minimum monthly rent				$ 2,000
Notice of termination period				30 days
Corporate Headquarter, Cambridge Massachusetts
Other Commitments [Line Items]
Lease term	4 months				4 months	4 months
Minimum monthly rent	$ 10,000
Rent expense recorded				$ 148,000
Willow Grove, PA Office Space
Other Commitments [Line Items]
Lease term		1 year
Minimum monthly rent		$ 2,200
Rent expense recorded				9,000
Philadelphia, PA Office Space
Other Commitments [Line Items]
Lease term	6 months				6 months	6 months
Minimum monthly rent				20,500
Rent expense recorded				$ 179,000
Majority Shareholder | Facility in Winnipeg, Manitola
Other Commitments [Line Items]
Lease square footage | ft²						31,100
Lease term	5 years			5 years	5 years	5 years
Number of renewal option			1	1
Minimum monthly rent				$ 12,400
Related operating expenses				13,300
Related party transaction, amounts of transaction			$ 86,000	$ 297,000	$ 320,000