Income Taxes - Reconciliation of Expected Income Tax Expense (Details)	12 Months Ended
Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Effective Income Tax Rate Reconciliation:
Income tax benefit computed at federal statutory tax rate	34.00%	34.00%	34.00%
Impact of foreign rate differential	(2.60%)	7.70%	0.00%
State taxes, net of federal benefit	1.40%	18.80%	5.60%
Net operating loss write off	0.00%	14.40%	0.00%
Stock option cancellations	(0.80%)	49.60%	0.00%
Transaction costs	0.00%	33.60%	0.00%
Contingent consideration	(10.70%)	(15.70%)	(0.00%)
General business credits and other credits	0.80%	(25.00%)	1.80%
Permanent differences	0.30%	5.30%	2.40%
Change in valuation allowance	28.20%	(122.40%)	(43.80%)
Federal statutory rate change	(50.60%)	0.00%	0.00%
Total	0.00%	0.30%	0.00%

Effective Income Tax Rate Reconciliation Contingent Consideration, Percent

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Effective Income Tax Rate Reconciliation, NOL write-off, Percent

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Effective Income Tax Rate Reconciliation Permanent Differences

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Effective Income Tax Rate Reconciliation, Transaction Costs, Percent

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Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations applicable to statutory income tax expense (benefit) outside of the country of domicile.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations applicable to state and local income tax expense (benefit), net of federal tax expense (benefit).

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