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Share-Based Payments - Fair Value of Stock Option Granted Estimated Using Black-Scholes Option-Pricing Model Assumptions - Employees (Details) - Employee Stock Options
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Risk-free interest rate, minimum (as a percent) 1.88% 1.23% 1.42%
Risk-free interest rate, maximum (as a percent) 2.04% 2.38% 1.92%
Expected dividend yield (as a percent) 0.00% 0.00% 0.00%
Expected volatility, minimum (as a percent) 75.40% 71.44% 69.06%
Expected volatility, maximum (as a percent) 86.66% 73.42% 74.11%
Minimum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term 6 years 3 months 18 days 5 years 6 months 5 years 9 months
Maximum      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term 6 years 6 years 6 years