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Business Combination - Schedule of Preliminary Purchase Price Consideration (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Sep. 20, 2016
Sep. 30, 2017
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Business Acquisition [Line Items]          
Adjustment     $ (14,600) $ 0 $ 0
Viventia Bio Inc.          
Business Acquisition [Line Items]          
Shares Issued     13,525 13,525  
Contingent Consideration     31,600 46,200  
Adjustment   $ (14,600)      
Fair value of consideration transferred $ 59,700   $ 45,125 $ 59,725