License Agreement with Roche (Details) $ in Thousands	3 Months Ended
Mar. 31, 2017 USD ($) unit_of_accounting	Mar. 31, 2016 USD ($)
Organization And Basis Of Presentation [Line Items]
Revenue recognized	$ 0	$ 229
Roche
Organization And Basis Of Presentation [Line Items]
Number of units of accounting \| unit_of_accounting	4
Revenue recognized	$ 400

Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.1)
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

Name:	us-gaap_Revenues
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration