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License Agreement with Roche - Additional Information (Details)
$ in Thousands
3 Months Ended 12 Months Ended
Jun. 10, 2016
USD ($)
option
accounting
Indication
Sep. 30, 2016
USD ($)
Sep. 15, 2016
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Organization And Basis Of Presentation [Line Items]            
Collaboration revenue       $ 406 $ 490 $ 2,243
Revenue allocated to transfer of pre-clinical inventory       425 $ 406  
Roche            
Organization And Basis Of Presentation [Line Items]            
License agreement, up-front fee $ 7,500          
License agreement, additional up-front fee $ 262,500          
License agreement, number of unrelated Indications | Indication 2          
License agreement, option periods | option 2          
License agreement, buyout amount under first option period $ 135,000          
License agreement, period to pay buyout option once exercised 30 days          
License agreement, buyout amount under second option period $ 265,000          
License agreement, buyout amount under second option period, upon non-issuance of patent rights or licensed product $ 220,000          
License agreement, period for termination where sufficient development activities are not performed 12 months          
Number of units of accounting | accounting 4          
Amount of allocable arrangement consideration $ 29,900          
Collaboration revenue   $ 29,000   29,600    
Revenue allocated to transfer of pre-clinical inventory       $ 400    
Roche | EBI-031 | Minimum            
Organization And Basis Of Presentation [Line Items]            
License agreement, royalty rate 7.50%          
Roche | EBI-031 | Maximum            
Organization And Basis Of Presentation [Line Items]            
License agreement, royalty rate 15.00%          
Roche | IL-6            
Organization And Basis Of Presentation [Line Items]            
License agreement, royalty rate 50.00%          
First Indication | Roche            
Organization And Basis Of Presentation [Line Items]            
License agreement, amount payable upon achievement of specified milestone $ 197,500          
Collaborative arrangement, revenue based on development milestone | Roche            
Organization And Basis Of Presentation [Line Items]            
License agreement, amount payable upon achievement of specified milestone 72,500          
Collaborative arrangement, revenue based on development milestone | Roche | EBI-031            
Organization And Basis Of Presentation [Line Items]            
License agreement, amount payable upon achievement of specified milestone     $ 22,500      
Collaborative arrangement, revenue based on regulatory milestone | Roche            
Organization And Basis Of Presentation [Line Items]            
License agreement, amount payable upon achievement of specified milestone 50,000          
Collaborative arrangement, revenue based on commercialization milestone | Roche            
Organization And Basis Of Presentation [Line Items]            
License agreement, amount payable upon achievement of specified milestone 75,000          
Second Indication | Roche            
Organization And Basis Of Presentation [Line Items]            
License agreement, amount payable upon achievement of specified milestone $ 65,000