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Organization and Basis of Presentation - Additional Information (Detail)
$ in Thousands
3 Months Ended
Sep. 20, 2016
USD ($)
shares
Jun. 10, 2016
USD ($)
option
Indication
Sep. 20, 2014
USD ($)
Sep. 15, 2016
USD ($)
Sep. 30, 2016
USD ($)
Dec. 31, 2015
USD ($)
Sep. 30, 2015
USD ($)
Dec. 31, 2014
USD ($)
Organization And Basis Of Presentation [Line Items]                
Cash and cash equivalents         $ 30,716 $ 36,079 $ 46,362 $ 54,059
Net working capital         25,500      
Accumulated deficit         $ (119,780) $ (125,202)    
Viventia Bio Inc.                
Organization And Basis Of Presentation [Line Items]                
Period during which quarterly earn-outs are payable after date of net sales 15 years   15 years          
Period in which acquiree is to use commercially reasonable efforts to achieve marketing authorizations 7 years              
Roche                
Organization And Basis Of Presentation [Line Items]                
Up-front license fee under license agreement   $ 7,500            
Additional Up-front fee (up to)   $ 262,500            
Number of unrelated indications (up to) | Indication   2            
Number of option periods provided under license agreement | option   2            
Buyout option following first closing of phase II   $ 135,000            
Buyout option following first closing of phase II, period   30 days            
Buyout option following day after initiation of phase III study   $ 265,000            
Buyout option upon non-issuance of patent rights or licensed product   $ 220,000            
Period for termination where sufficient development activities are not performed   12 months            
First Indication | Roche                
Organization And Basis Of Presentation [Line Items]                
Amount payable upon achievement of specified milestone (up to)   $ 197,500            
Development Milestone | Roche                
Organization And Basis Of Presentation [Line Items]                
Amount payable upon achievement of specified milestone (up to)   72,500            
Regulatory Milestone | Roche                
Organization And Basis Of Presentation [Line Items]                
Amount payable upon achievement of specified milestone (up to)   50,000            
Commercialization Milestone | Roche                
Organization And Basis Of Presentation [Line Items]                
Amount payable upon achievement of specified milestone (up to)   75,000            
Second Indication | Roche                
Organization And Basis Of Presentation [Line Items]                
Amount payable upon achievement of specified milestone (up to)   $ 65,000            
Vicinium | Specified Milestone | Viventia Bio Inc.                
Organization And Basis Of Presentation [Line Items]                
Percentage of net sales of quarterly earn-out payments during earn-out periods 2.00%   2.00%          
EBI-031 | Minimum | Roche                
Organization And Basis Of Presentation [Line Items]                
Royalty percentage for future products containing EBI-031   7.50%            
EBI-031 | Maximum | Roche                
Organization And Basis Of Presentation [Line Items]                
Royalty percentage for future products containing EBI-031   15.00%            
EBI-031 | Development Milestone | Roche                
Organization And Basis Of Presentation [Line Items]                
Amount payable upon achievement of specified milestone (up to)       $ 22,500        
IL-6 | Roche                
Organization And Basis Of Presentation [Line Items]                
Royalty percentage for future products containing EBI-031   50.00%            
Viventia Bio Inc.                
Organization And Basis Of Presentation [Line Items]                
Common stock issued to selling shareholders (in shares) | shares 4,013,431              
Percentage of voting interests acquired 19.90%              
Equity interest issued and issuable, equity shares deposited into an escrow account per acquiree (in shares) | shares 401,343              
Percentage of common stock owned by acquiree at closing of the share purchase agreement 10.00%              
UNITED STATES | Vicinium | Specified Milestone | Viventia Bio Inc.                
Organization And Basis Of Presentation [Line Items]                
One-time milestone payment upon first sale of product $ 12,500   $ 12,500          
Europe | Vicinium | Specified Milestone | Viventia Bio Inc.                
Organization And Basis Of Presentation [Line Items]                
One-time milestone payment upon first sale of product 7,000   7,000          
JAPAN | Vicinium | Specified Milestone | Viventia Bio Inc.                
Organization And Basis Of Presentation [Line Items]                
One-time milestone payment upon first sale of product $ 3,000   $ 3,000