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Selected Quarterly Financial Data (Unaudited)
 12 Months Ended
Dec. 31, 2015
Quarterly Financial Information Disclosure [Abstract]  
Selected Quarterly Financial Data (Unaudited)
Selected Quarterly Financial Data (Unaudited)
The following table contains quarterly financial information for 2015 and 2014. The Company believes that the following information reflects all normal recurring adjustments necessary for a fair statement of the information for the periods presented. The operating results for any quarter are not necessarily indicative of results for any future period.
 
2015
 
First
Quarter
 
Second
Quarter
 
Third
Quarter
 
Fourth
Quarter
 
Total
 
(in thousands, except per share data)
Total revenue
$
244

 
$
114

 
$
67

 
$
565

 
$
990

Total operating expenses
7,841

 
8,516

 
9,426

 
10,403

 
36,186

Loss from operations
(7,597
)
 
(8,402
)
 
(9,359
)
 
(9,838
)
 
(35,196
)
Net loss
(6,524
)
 
(6,906
)
 
(9,693
)
 
(10,329
)
 
(33,452
)
Net loss applicable to common stockholders
(6,524
)
 
(6,906
)
 
(9,693
)
 
(10,329
)
 
(33,452
)
Net loss per share applicable to common stockholders—basic and diluted
$
(0.36
)
 
$
(0.36
)
 
$
(0.50
)
 
$
(0.53
)
 
$
(1.76
)

 
2014
 
First
Quarter
 
Second
Quarter
 
Third
Quarter
 
Fourth
Quarter
 
Total
 
(in thousands, except per share data)
Total revenue
$
568

 
$
761

 
$
539

 
$
375

 
$
2,243

Total operating expenses
7,757

 
8,806

 
11,141

 
7,470

 
35,174

Loss from operations
(7,189
)
 
(8,045
)
 
(10,602
)
 
(7,095
)
 
(32,931
)
Net loss
(7,222
)
 
(8,121
)
 
(10,674
)
 
(8,139
)
 
(34,156
)
Net loss applicable to common stockholders
(7,741
)
 
(8,121
)
 
(10,674
)
 
(8,139
)
 
(34,675
)
Net loss per share applicable to common stockholders—basic and diluted
$
(0.80
)
 
$
(0.51
)
 
$
(0.66
)
 
$
(0.49
)
 
$
(2.37
)