Moderna Collaboration and License Agreement - Changes in deferred revenue (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Moderna Collaboration and License Agreement
Balance at the beginning of the period	$ 47,459
Deferral of revenue	2,920	$ 46,441
Recognition of unearned revenue	(3,243)	(822)
Balance at the ending of the period	$ 47,136	$ 45,619