<SEC-DOCUMENT>0001104659-23-022869-index.html : 20230216
<SEC-HEADER>0001104659-23-022869.hdr.sgml : 20230216
<ACCEPTANCE-DATETIME>20230216170526
ACCESSION NUMBER:		0001104659-23-022869
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20230216
DATE AS OF CHANGE:		20230216

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Sesen Bio, Inc.
		CENTRAL INDEX KEY:			0001485003
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				262025616
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-267891
		FILM NUMBER:		23639275

	BUSINESS ADDRESS:	
		STREET 1:		245 FIRST STREET
		STREET 2:		SUITE 1800
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		617-444-8550

	MAIL ADDRESS:	
		STREET 1:		245 FIRST STREET
		STREET 2:		SUITE 1800
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Eleven Biotherapeutics, Inc.
		DATE OF NAME CHANGE:	20100223
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B3
<SEQUENCE>1
<FILENAME>tm236507-3_424b3.htm
<DESCRIPTION>424B3
<TEXT>
Document 1 - file: tm236507-3_424b3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>lg_sesenbio-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: lg_sesenbio-4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>lg_carismatherapeutics-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: lg_carismatherapeutics-4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>lg_mackenziepartners-bw.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: lg_mackenziepartners-bw.jpg

</DOCUMENT>
</SEC-DOCUMENT>