<SEC-DOCUMENT>0001104659-23-021675-index.html : 20230214
<SEC-HEADER>0001104659-23-021675.hdr.sgml : 20230214
<ACCEPTANCE-DATETIME>20230214162152
ACCESSION NUMBER:		0001104659-23-021675
CONFORMED SUBMISSION TYPE:	S-4MEF
PUBLIC DOCUMENT COUNT:		7
<REFERENCE-462B>333-267891
FILED AS OF DATE:		20230214
DATE AS OF CHANGE:		20230214
EFFECTIVENESS DATE:		20230214

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Sesen Bio, Inc.
		CENTRAL INDEX KEY:			0001485003
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				262025616
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-4MEF
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-269761
		FILM NUMBER:		23629815

	BUSINESS ADDRESS:	
		STREET 1:		245 FIRST STREET
		STREET 2:		SUITE 1800
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		617-444-8550

	MAIL ADDRESS:	
		STREET 1:		245 FIRST STREET
		STREET 2:		SUITE 1800
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Eleven Biotherapeutics, Inc.
		DATE OF NAME CHANGE:	20100223
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-4MEF
<SEQUENCE>1
<FILENAME>tm236773d1_s4mef.htm
<DESCRIPTION>S-4MEF
<TEXT>
Document 1 - file: tm236773d1_s4mef.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>tm236773d1_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 2 - file: tm236773d1_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>3
<FILENAME>tm236773d1_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
Document 3 - file: tm236773d1_ex23-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.3
<SEQUENCE>4
<FILENAME>tm236773d1_ex23-3.htm
<DESCRIPTION>EXHIBIT 23.3
<TEXT>
Document 4 - file: tm236773d1_ex23-3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>5
<FILENAME>tm236773d1_ex99-1.htm
<DESCRIPTION>EXHIBIT 99.1
<TEXT>
Document 5 - file: tm236773d1_ex99-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>6
<FILENAME>tm236773d1_ex-filingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 6 - file: tm236773d1_ex-filingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>tm236773d1_ex5-1img01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: tm236773d1_ex5-1img01.jpg

</DOCUMENT>
</SEC-DOCUMENT>