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INCOME TAXES - Reconciliation of Expected Income Tax Expense (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Effective Income Tax Rate Reconciliation:      
United States federal statutory income tax rate 21.00% 21.00% 21.00%
Impact of foreign rate differential (15.90%) (4.20%) 4.40%
State taxes, net of federal benefit 2.30% 2.00% 0.60%
Stock option cancellations (1.10%) (0.20%) 0.00%
Contingent consideration 178.20% 14.40% (18.00%)
General business credits and other credits 2.40% 6.60% 0.40%
Permanent differences (1.40%) 0.20% 0.00%
Other (13.80%) (2.10%) (0.50%)
Foreign taxes (3.30%) (6.90%)  
Change in valuation allowance (72.30%) (37.70%) (7.90%)
Effective Income Tax Rate 96.10% (6.90%) 0.00%