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CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (DEFICIT) - USD ($)
$ in Thousands
Common Stock [Member]
ATM Facility [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
ATM Facility [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
ATM Facility [Member]
Total
Beginning balance (in shares) at Dec. 31, 2018   77,456,180          
Beginning balance at Dec. 31, 2018   $ 77   $ 230,154 $ (186,024)   $ 44,207
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss         (107,500)   (107,500)
Share-based compensation       1,237     $ 1,237
Exercise of stock options (in shares)   89,812         90,000
Exercises of stock options       98     $ 98
Sales of common stock under 2014 ESPP (in shares)   10,283          
Sales of common stock under 2014 ESPP       8     8
Exercise of common stock warrants (in shares)   6,772,928          
Exercise of common stock warrants   $ 7   5,474     5,481
Issuance of common stock and common stock warrants (in shares) 2,062,206 20,410,000          
Issuance of common stock and common stock warrants $ 2 $ 21 $ 1,934 27,812   $ 1,936 27,833
Ending balance (in shares) at Dec. 31, 2019   106,801,409          
Ending balance at Dec. 31, 2019   $ 107   266,717 (293,524)   (26,700)
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss         (22,397)   (22,397)
Share-based compensation       1,757     $ 1,757
Exercise of stock options (in shares)   12,000         12,000
Exercises of stock options       13     $ 13
Sales of common stock under 2014 ESPP (in shares)   28,186          
Sales of common stock under 2014 ESPP       11     11
Exercise of common stock warrants (in shares)   238,110          
Exercise of common stock warrants       131     131
Issuance of common stock and common stock warrants (in shares) 33,369,942            
Issuance of common stock and common stock warrants $ 33   37,925     37,958  
Ending balance (in shares) at Dec. 31, 2020   140,449,647          
Ending balance at Dec. 31, 2020   $ 140   306,554 (315,921)   (9,227)
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss         (55,512)   (55,512)
Share-based compensation       958     958
Exercise of stock options (in shares)   30,610          
Exercises of stock options       39     39
Exercise of common stock warrants (in shares)   852,840          
Exercise of common stock warrants   $ 1   468     469
Issuance of common stock and common stock warrants (in shares) 30,645,702            
Issuance of common stock and common stock warrants $ 31   72,512     72,543  
Ending balance (in shares) at Mar. 31, 2021   171,978,799          
Ending balance at Mar. 31, 2021   $ 172   380,531 (371,433)   9,270
Beginning balance (in shares) at Dec. 31, 2020   140,449,647          
Beginning balance at Dec. 31, 2020   $ 140   306,554 (315,921)   (9,227)
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss             (9,280)
Ending balance (in shares) at Sep. 30, 2021   199,463,645          
Ending balance at Sep. 30, 2021   $ 199   486,010 (325,201)   161,008
Beginning balance (in shares) at Dec. 31, 2020   140,449,647          
Beginning balance at Dec. 31, 2020   $ 140   306,554 (315,921)   (9,227)
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss         (336)   (336)
Share-based compensation       5,143     $ 5,143
Exercise of stock options (in shares)   33,610         34,000
Exercises of stock options       42     $ 42
Exercise of common stock warrants (in shares)   2,048,059         2,048,000
Exercise of common stock warrants   $ 2   1,124     $ 1,126
Issuance of common stock and common stock warrants (in shares) 56,932,329            
Issuance of common stock and common stock warrants $ 57   174,905     174,962  
Ending balance (in shares) at Dec. 31, 2021   199,463,645          
Ending balance at Dec. 31, 2021   $ 199   487,768 (316,257)   171,710
Beginning balance (in shares) at Mar. 31, 2021   171,978,799          
Beginning balance at Mar. 31, 2021   $ 172   380,531 (371,433)   9,270
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss         (25,442)   (25,442)
Share-based compensation       1,260     1,260
Issuance of common stock and common stock warrants (in shares) 16,482,152            
Issuance of common stock and common stock warrants $ 16   64,245     64,261  
Ending balance (in shares) at Jun. 30, 2021   188,460,951          
Ending balance at Jun. 30, 2021   $ 188   446,036 (396,875)   49,349
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss         71,674   71,674
Share-based compensation       1,168     1,168
Exercise of stock options (in shares)   3,000          
Exercises of stock options       3     3
Exercise of common stock warrants (in shares)   1,195,219          
Exercise of common stock warrants   $ 1   656     657
Issuance of common stock and common stock warrants (in shares) 9,804,475            
Issuance of common stock and common stock warrants $ 10   $ 38,147     $ 38,157  
Ending balance (in shares) at Sep. 30, 2021   199,463,645          
Ending balance at Sep. 30, 2021   $ 199   486,010 (325,201)   161,008
Beginning balance (in shares) at Dec. 31, 2021   199,463,645          
Beginning balance at Dec. 31, 2021   $ 199   487,768 (316,257)   171,710
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss         (807)   (807)
Share-based compensation       1,894     1,894
Ending balance (in shares) at Mar. 31, 2022   199,463,645          
Ending balance at Mar. 31, 2022   $ 199   489,662 (317,064)   172,797
Beginning balance (in shares) at Dec. 31, 2021   199,463,645          
Beginning balance at Dec. 31, 2021   $ 199   487,768 (316,257)   171,710
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss             $ (12,310)
Exercise of stock options (in shares)             0
Exercise of common stock warrants (in shares)             0
Ending balance (in shares) at Sep. 30, 2022   202,757,012          
Ending balance at Sep. 30, 2022   $ 202   493,629 (328,567)   $ 165,029
Beginning balance (in shares) at Mar. 31, 2022   199,463,645          
Beginning balance at Mar. 31, 2022   $ 199   489,662 (317,064)   172,797
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss         (31,960)   (31,960)
Share-based compensation       1,802     1,802
Ending balance (in shares) at Jun. 30, 2022   199,463,645          
Ending balance at Jun. 30, 2022   $ 199   491,464 (349,024)   142,358
Increase (Decrease) in Stockholders' Equity [Roll Forward]              
Net loss         20,457   20,457
Share-based compensation   $ 3   2,165     2,168
Ending balance (in shares) at Sep. 30, 2022   202,757,012          
Ending balance at Sep. 30, 2022   $ 202   $ 493,629 $ (328,567)   $ 165,029