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FAIR VALUE MEASUREMENT AND FINANCIAL INSTRUMENTS - Narrative (Details)
$ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2022
USD ($)
Dec. 31, 2021
USD ($)
Sep. 30, 2021
USD ($)
Jun. 30, 2021
USD ($)
Mar. 31, 2021
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Dec. 31, 2021
item
Fair Value, Option, Quantitative Disclosures [Line Items]                      
Contingent consideration liability, measurement input   0.080 0.075 0.066 0.074   0.075 0.080 0.084   0.080
License agreement, royalty rate 2.00% 2.00%       2.00%   2.00%      
Change in fair value of contingent consideration $ (1,800) $ (4,600) $ (114,000) $ 13,600 $ 48,160 $ (52,000) $ (52,240) $ (56,840) $ (11,180) $ 71,620  
Minimum                      
Fair Value, Option, Quantitative Disclosures [Line Items]                      
Probability of achieving clinical and regulatory milestones   45.00%           45.00%      
Maximum                      
Fair Value, Option, Quantitative Disclosures [Line Items]                      
Probability of achieving clinical and regulatory milestones   55.00%           55.00%      
Discount Rate                      
Fair Value, Option, Quantitative Disclosures [Line Items]                      
Weighted-average cost of capital   9.30% 8.60% 6.80% 7.80%   8.60% 9.30% 8.80%    
Discount Rate | Minimum                      
Fair Value, Option, Quantitative Disclosures [Line Items]                      
Contingent consideration liability, measurement input   0.080           0.080 0.084   0.080
Discount Rate | Maximum                      
Fair Value, Option, Quantitative Disclosures [Line Items]                      
Contingent consideration liability, measurement input   0.093           0.093 0.088   0.093