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Document and Entity Information - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2021
Mar. 24, 2022
Jun. 30, 2021
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2021    
Document Fiscal Year Focus 2021    
Document Fiscal Period Focus FY    
Entity Registrant Name SOLENO THERAPEUTICS INC    
Entity Central Index Key 0001484565    
Current Fiscal Year End Date --12-31    
Entity Well-known Seasoned Issuer No    
Entity Current Reporting Status Yes    
Entity Voluntary Filers No    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Shell Company false    
Entity Emerging Growth Company false    
Document Annual Report true    
Document Transition Report false    
Entity File Number 001-36593    
Entity Tax Identification Number 77-0523891    
Entity Address, Address Line One 203 Redwood Shores Parkway    
Entity Address, Address Line Two Suite 500    
Entity Address, City or Town Redwood City    
Entity Address, State or Province CA    
Entity Address, Postal Zip Code 94065    
City Area Code 650    
Local Phone Number 213-8444    
Entity Incorporation, State or Country Code DE    
Entity Common Stock, Shares Outstanding   80,088,816  
Entity Public Float     $ 61.3
Auditor Name Marcum LLP    
Auditor Location San Francisco, CA    
Auditor Firm ID 688    
Title of 12(b) Security Common Stock, $0.001 par value    
Trading Symbol SLNO    
Security Exchange Name NASDAQ    
Documents Incorporated by Reference

DOCUMENTS INCORPORATED BY REFERENCE

Portions of the registrant’s Definitive Proxy Statement to be filed with the Commission pursuant to Regulation 14A in connection with the registrant’s 2022 Annual Meeting of Stockholders, to be filed subsequent to the date hereof, are incorporated by reference into Part III of this Report. Such Definitive Proxy Statement will be filed with the Securities and Exchange Commission not later than 120 days after the conclusion of the registrant’s fiscal year ended December 31, 2021. Except with respect to information specifically incorporated by reference in this Form 10-K, the Proxy Statement is not deemed to be filed as part of this Form 10-K.