CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
Product revenues, net	$ 420	$ 3,067	$ 3,892	$ 9,384
Costs and expenses:
Cost of product revenues	11	908	2,560	2,679
Selling, general and administrative	9,549	25,349	59,204	81,034
Research and development	5,391	2,881	14,330	9,101
(Gain) loss on fair value remeasurement of deferred purchase consideration	(57)		205
Loss (gain) on fair value remeasurement of contingent consideration	95		(952)
Total costs and expenses	14,989	29,138	75,347	92,814
Loss from operations	(14,569)	(26,071)	(71,455)	(83,430)
Other income (expense):
Interest income	234	16	310	92
Interest expense	(1,447)	(2,072)	(5,689)	(6,304)
Loss on extinguishment of debt	(2,583)		(2,583)	(5,395)
Gain on sale of commercial business	46,995		46,995
Other income (expense), net	443		443
Total interest and other income (expense)	43,642	(2,056)	39,476	(11,607)
Net income (loss)	$ 29,073	$ (28,127)	$ (31,979)	$ (95,037)
Net income (loss) per share-basic (in dollar per share)	$ 19.39	$ (21.41)	$ (21.46)	$ (73.80)
Net income (loss) per share- diluted (in dollar per share)	$ 19.25	$ (21.41)	$ (21.46)	$ (73.80)
Weighted average shares outstanding-basic (in shares)	1,499,001	1,313,466	1,490,159	1,287,772
Weighted average shares outstanding-diluted (in shares)	1,510,421	1,313,466	1,490,159	1,287,772
Statement of Comprehensive Income (Loss)
Net income (loss)	$ 29,073	$ (28,127)	$ (31,979)	$ (95,037)
Other comprehensive income (loss):
Change in unrealized gains on investments	1			(4)
Total other comprehensive income (loss)	1			(4)
Total comprehensive income (loss)	$ 29,074	$ (28,127)	$ (31,979)	$ (95,041)