Amount receivable upon the achievement of specified commercial sales-based milestones.

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Redeemable preferred stock dividend declared ratio for each outstanding shares.

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Aggregate dividends paid during the period for each whole share of redeemable preferred stock outstanding.

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Represents number of shares in whole shares.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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The maximum number of common shares permitted to be issued by an entity's charter and bylaws.

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The cumulative amount of the reporting entity's undistributed earnings or deficit.

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Ratio applied to the conversion of stock split, for example but not limited to, one share converted to two or two shares converted to one.

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The number of securities classified as temporary equity that have been sold (or granted) to the entity's shareholders. Securities issued include securities outstanding and securities held in treasury. Temporary equity is a security with redemption features that are outside the control of the issuer, is not classified as an asset or liability in conformity with GAAP, and is not mandatorily redeemable. Includes any type of security that is redeemable at a fixed or determinable price or on a fixed or determinable date or dates, is redeemable at the option of the holder, or has conditions for redemption which are not solely within the control of the issuer. If convertible, the issuer does not control the actions or events necessary to issue the maximum number of shares that could be required to be delivered under the conversion option if the holder exercises the option to convert the stock to another class of equity. If the security is a warrant or a rights issue, the warrant or rights issue is considered to be temporary equity if the issuer cannot demonstrate that it would be able to deliver upon the exercise of the option by the holder in all cases. Includes stock with put option held by ESOP and stock redeemable by holder only in the event of a change in control of the issuer.

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The number of securities classified as temporary equity that have been issued and are held by the entity's shareholders. Securities outstanding equals securities issued minus securities held in treasury. Temporary equity is a security with redemption features that are outside the control of the issuer, is not classified as an asset or liability in conformity with GAAP, and is not mandatorily redeemable. Includes any type of security that is redeemable at a fixed or determinable price or on a fixed or determinable date or dates, is redeemable at the option of the holder, or has conditions for redemption which are not solely within the control of the issuer. If convertible, the issuer does not control the actions or events necessary to issue the maximum number of shares that could be required to be delivered under the conversion option if the holder exercises the option to convert the stock to another class of equity. If the security is a warrant or a rights issue, the warrant or rights issue is considered to be temporary equity if the issuer cannot demonstrate that it would be able to deliver upon the exercise of the option by the holder in all cases. Includes stock with put option held by ESOP and stock redeemable by holder only in the event of a change in control of the issuer.

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NATURE OF BUSINESS AND BASIS OF PRESENTATION (Details) $ / shares in Units, $ in Thousands	Oct. 22, 2022 shares	Oct. 19, 2022 $ / shares shares	Nov. 03, 2022 shares	Sep. 30, 2022 USD ($) shares	Aug. 18, 2022	Jul. 08, 2022 USD ($)	Dec. 31, 2021 USD ($) shares
Acquisition of Combangio, Inc
Common stock, authorized				120,000,000			120,000,000
Accumulated deficit \| $				$ 574,367			$ 542,388
Subsequent Events
Acquisition of Combangio, Inc
Reverse stock split	0.02
Common stock, authorized	120,000,000
Series D redeemable preferred stock
Acquisition of Combangio, Inc
Shares Issued				73,208			0
Shares Outstanding				73,208			0
Redeemable preferred stock dividend declared ratio					0.001
Series D redeemable preferred stock \| Subsequent Events
Acquisition of Combangio, Inc
Shares Outstanding			0
Aggregate dividends paid during the period for each whole share of redeemable preferred stock outstanding \| $ / shares		$ 0.10
Number of shares in whole shares		100
Commercial Business Sale to Alcon \| Disposed of by sale not discontinued operations
Acquisition of Combangio, Inc
Amount receivable upon the achievement of specified commercial sales-based milestones \| $						$ 325,000