The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Alcobra Ltd | COM | M2239P109 | 2,534 | 450,000 | SH | SOLE | 450,000 | 0 | 0 | ||
| Alcobra Ltd | COM | M2239P109 | 5,912 | 1,050,000 | SH | DFND | 1,050,000 | 0 | 0 | ||
| Anacor Pharmaceuticals Inc | COM | 032420101 | 68,175 | 1,178,474 | SH | SOLE | 1,178,474 | 0 | 0 | ||
| Ascendis Pharma A/S | COM | 04351P101 | 1,562 | 90,000 | SH | SOLE | 90,000 | 0 | 0 | ||
| Ascendis Pharma A/S | COM | 04351P101 | 11,349 | 721,152 | SH | DFND | 721,152 | 0 | 0 | ||
| Avalanche Biotechnologies Inc | COM | 05337G107 | 44,683 | 1,102,735 | SH | SOLE | 1,102,735 | 0 | 0 | ||
| Avalanche Biotechnologies Inc | COM | 05337G107 | 11,346 | 280,000 | SH | DFND | 280,000 | 0 | 0 | ||
| BioCryst Pharmaceuticals Inc | COM | 09058V103 | 15,752 | 1,744,356 | SH | SOLE | 1,744,356 | 0 | 0 | ||
| Coherus Biosciences Inc | COM | 19249H103 | 18,090 | 611,010 | SH | SOLE | 611,010 | 0 | 0 | ||
| Coherus Biosciences Inc | COM | 19249H103 | 7,928 | 259,259 | SH | DFND | 259,259 | 0 | 0 | ||
| Cynapsus Therapeutics Inc | COM | 23257Y701 | 1,536 | 1,763,657 | SH | SOLE | 1,763,657 | 0 | 0 | ||
| Cynapsus Therapeutics Inc | COM | 23257Y701 | 3,585 | 4,115,198 | SH | DFND | 4,115,198 | 0 | 0 | ||
| DBV Technologies | COM | F2927N109 | 20,591 | 463,643 | SH | SOLE | 463,643 | 0 | 0 | ||
| DBV Technologies | COM | F2927N109 | 8,981 | 230,167 | SH | DFND | 230,167 | 0 | 0 | ||
| Dyax Corp | COM | 26746E103 | 16,766 | 1,000,659 | SH | SOLE | 1,000,659 | 0 | 0 | ||
| Flamel Technologies S.A. | COM | 338488109 | 8,990 | 500,000 | SH | SOLE | 500,000 | 0 | 0 | ||
| GW Pharmaceuticals | COM | 36197T103 | 28,419 | 311,853 | SH | SOLE | 311,853 | 0 | 0 | ||
| Heron Therapeutics Inc | COM | 427746102 | 15,943 | 1,095,734 | SH | SOLE | 1,095,734 | 0 | 0 | ||
| Juno Therapeutics Inc | COM | 48205A109 | 96,955 | 1,749,999 | SH | SOLE | 1,749,999 | 0 | 0 | ||
| Lipocine Inc | COM | 53630X104 | 4,622 | 669,921 | SH | SOLE | 669,921 | 0 | 0 | ||
| Ocera Therapeutics | COM | 67552A108 | 3,315 | 703,730 | SH | SOLE | 703,730 | 0 | 0 | ||
| Stemline Therapeutics Inc | COM | 85858C107 | 1,960 | 135,420 | SH | SOLE | 135,420 | 0 | 0 | ||
| Stemline Therapeutics Inc | COM | 85858C107 | 4,572 | 315,980 | SH | DFND | 315,980 | 0 | 0 | ||
| TherapeuticsMD Inc | COM | 88338N107 | 5,121 | 846,500 | SH | SOLE | 846,500 | 0 | 0 | ||
| Zafgen Inc | COM | 98885E103 | 21,448 | 541,480 | SH | SOLE | 541,480 | 0 | 0 | ||
| ZS Pharma Inc | COM | 98979G105 | 4,208 | 100,000 | SH | SOLE | 100,000 | 0 | 0 | ||