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The Company and Basis of Presentation - Additional Information (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Dec. 31, 2012
Dec. 31, 2014
Organization, Consolidation and Presentation of Financial Statements [Abstract]            
Company's incorporation date     Aug. 10, 1999      
Commencement date of operations     Jun. 30, 2002      
Change of entity name date     Apr. 19, 2005      
Net loss $ 16,805 $ 13,302 $ 32,207 $ 34,728 $ 32,207  
Net cash used in operating activities     25,512 $ 33,260    
Working capital surplus 127,100   127,100      
Accumulated deficit (291,004)   (291,004)     $ (258,797)
Cash, cash equivalents, and investments $ 149,400   $ 149,400      
Cash and cash equivalents, and investments, expected funding term for operating plan     12 months