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In-Process Research and Development (Details) - USD ($)
3 Months Ended 9 Months Ended
Jun. 02, 2016
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Payment for acquisition of in-process research and development $ 1,800,000     $ 1,800,000 $ 0
Holdback related to acquisition of in-process research and development 200,000     200,000 0
Research and development 2,000,000 $ 10,296,000 $ 13,016,000 $ 37,851,000 $ 32,573,000
Botulinum Toxin Research Associates, Inc.          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Accrued milestone obligations $ 16,000,000.0