Income Taxes (Tables)

12 Months Ended

Dec. 31, 2021

Income Tax Disclosure [Abstract]

Schedule of Components of Loss Before Provision for Income Taxes

The components of loss before provision for income taxes for the periods presented are as follows (in thousands):

	Year Ended December 31,
	2021			2020			2019
Domestic	$	(207,314	)	$	(146,227	)	$	(68,606	)
Foreign		16			—			—
Total loss before provision for income taxes	$	(207,298	)	$	(146,227	)	$	(68,606	)

Schedule of Components of Deferred Tax Assets and Liabilities

The significant components of our deferred tax assets and liabilities as of the dates presented are as follows (in thousands):

	December 31,
	2021			2020
Deferred tax assets
Net operating losses	$	200,363		$	105,433
Tax credit carryforward		31,200			18,981
Nonqualifying stock options		18,072			12,096
Deferred rent		—			—
Operating lease liabilities		30,401			31,052
Deferred revenue		42,481			59,713
Other		4,345			2,983
Total deferred tax assets		326,862			230,258
Less: Valuation allowance		(297,020	)		(197,527	)
Deferred tax assets, net of valuation allowance		29,842			32,731
Deferred tax liabilities
Tangible and intangible assets		(7,310	)		(5,760	)
ROU assets		(22,532	)		(26,971	)
Net deferred taxes	$	—		$	—

Schedule of Reconciliation of Effective Tax Rate of Provision for Income Taxes Differs from Federal Statutory Rate

The effective tax rate of our provision for income taxes differs from the federal statutory rate for the periods presented as follows:

	Year Ended December 31,
	2021	2020	2019
Statutory rate	21.0%	21.0%	21.0%
State tax, net of federal tax benefit	8.3	13.8	8.1
Stock compensation	14.1	25.2	9.8
Permanent items	(0.1)	(0.1)	(1.0)
Credits	4.7	5.7	6.1
Other	(0.3)	0.5	0.3
Change in valuation allowance	(47.7)	(66.1)	(44.3)
Total	0.0%	0.0%	0.0%

Schedule of Change in Unrecognized Tax Benefits

A reconciliation of the beginning and ending amounts of unrecognized tax benefits for the dates presented are as follows (in thousands):

Balance at December 31, 2018	$	1,260
Additions in 2019		792
Balance at December 31, 2019		2,052
Additions in 2020		1,437
Balance at December 31, 2020		3,489
Additions in 2021		3,426
Balance at December 31, 2021	$	6,915