10-Q

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 10-Q

(Mark One)

x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended September 30, 2014

or

¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from            to             .

Commission File Number: 001-35907

QUINTILES TRANSNATIONAL HOLDINGS INC.

(Exact name of registrant as specified in its charter)

North Carolina	27-1341991
(State or other jurisdiction of incorporation or organization)	(I.R.S. Employer Identification Number)

4820 Emperor Blvd., Durham, North Carolina 27703

(Address of principal executive offices and Zip Code)

(919) 998-2000

(Registrant’s telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.    Yes  x    No  ¨

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).    Yes  x    No  ¨

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See definition of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer	¨	Accelerated filer	¨
Non-accelerated filer	x  (Do not check if a smaller reporting company)	Smaller reporting company	¨

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).    Yes  ¨    No  x

Indicate the number of shares outstanding of each of the issuer’s classes of Common Stock, as of the latest practicable date.

Class	Number of Shares Outstanding
Common Stock $0.01 par value	127,799,825 shares outstanding as of October 23, 2014

QUINTILES TRANSNATIONAL HOLDINGS INC.

FORM 10-Q

TABLE OF CONTENTS

		Page
PART I—FINANCIAL INFORMATION			3
Item 1.	Financial Statements (unaudited)		3
	Condensed Consolidated Statements of Income for the three and nine months ended September 30, 2014 and 2013		3
	Condensed Consolidated Statements of Comprehensive Income for the three and nine months ended September 30, 2014 and 2013		4
	Condensed Consolidated Balance Sheets as of September 30, 2014 and December 31, 2013		5
	Condensed Consolidated Statements of Cash Flows for the nine months ended September 30, 2014 and 2013		6
	Notes to Condensed Consolidated Financial Statements		7
Item 2.	Management’s Discussion and Analysis of Financial Condition and Results of Operations		16
Item 3.	Quantitative and Qualitative Disclosures About Market Risk		27
Item 4.	Controls and Procedures		27
PART II—OTHER INFORMATION			27
Item 1.	Legal Proceedings		27
Item 1A.	Risk Factors		27
Item 2.	Unregistered Sales of Equity Securities, Use of Proceeds and Issuer Purchases of Equity Securities		27
Item 6.	Exhibits		28
SIGNATURES			29
EXHIBIT INDEX			30

2

PART I—FINANCIAL INFORMATION

Item 1. Financial Statements

QUINTILES TRANSNATIONAL HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF INCOME

(unaudited)

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(in thousands, except per share data)
Service revenues	$	1,061,013	$	932,727	$	3,101,777	$	2,804,400
Reimbursed expenses		339,021		263,112		947,133		915,960
Total revenues		1,400,034		1,195,839		4,048,910		3,720,360
Costs of revenue, service costs		691,051		600,694		2,009,287		1,829,469
Costs of revenue, reimbursed expenses		339,021		263,112		947,133		915,960
Selling, general and administrative		219,027		199,573		657,283		627,713
Restructuring costs		1,793		7,201		3,749		11,897
Income from operations		149,142		125,259		431,458		335,321
Interest income		(602)		(1,119)		(2,851)		(2,356)
Interest expense		25,050		28,756		74,552		96,682
Loss on extinguishment of debt		—		—		—		16,543
Other (income) expense, net		(7,776)		3,224		(9,564)		1,378
Income before income taxes and equity in earnings (losses) of unconsolidated affiliates		132,470		94,398		369,321		223,074
Income tax expense		41,260		27,459		111,049		68,407
Income before equity in earnings (losses) of unconsolidated affiliates		91,210		66,939		258,272		154,667
Equity in earnings (losses) of unconsolidated affiliates		1,523		(355)		9,785		(1,574)
Net income		92,733		66,584		268,057		153,093
Net (income) loss attributable to noncontrolling interests		(79)		185		(100)		502
Net income attributable to Quintiles Transnational Holdings Inc.	$	92,654	$	66,769	$	267,957	$	153,595
Earnings per share attributable to common shareholders:
Basic	$	0.73	$	0.52	$	2.08	$	1.25
Diluted	$	0.71	$	0.50	$	2.03	$	1.22
Weighted average common shares outstanding:
Basic		127,462		128,923		128,780		122,467
Diluted		130,626		133,267		131,903		126,195

The accompanying notes are an integral part of these condensed consolidated financial statements.

3

QUINTILES TRANSNATIONAL HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME

(unaudited)

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(in thousands)
Net income	$	92,733	$	66,584	$	268,057	$	153,093
Unrealized (losses) gains on marketable securities, net of income taxes of ($4), $821, ($294) and $847		(6)		1,315		(469)		1,357
Unrealized (losses) gains on derivative instruments, net of income taxes of ($882), $159, ($990) and ($815)		(3,561)		2,126		(2,311)		(574)
Foreign currency translation, net of income taxes of ($1,408), ($2,048), ($1,408) and ($2,378)		(27,280)		8,622		(23,116)		(19,732)
Reclassification adjustments:
Gains on marketable securities included in net income, net of income taxes of ($1,927)		—		—		(3,077)		—
Losses on derivative instruments included in net income, net of income taxes of $1,086, $1,285, $2,616 and $3,973		1,449		2,084		1,945		6,902
Amortization of prior service costs and losses included in net income, net of income taxes of $70, $95, $214 and $290		117		157		358		478
Comprehensive income		63,452		80,888		241,387		141,524
Comprehensive (income) loss attributable to noncontrolling interests		(87)		175		(99)		484
Comprehensive income attributable to Quintiles Transnational Holdings Inc.	$	63,365	$	81,063	$	241,288	$	142,008

The accompanying notes are an integral part of these condensed consolidated financial statements.

4

QUINTILES TRANSNATIONAL HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED BALANCE SHEETS

	September 30,   2014		December 31,   2013
	(unaudited)		(Note 1)
	(in thousands, except per share data)
ASSETS
Current assets:
Cash and cash equivalents	$	645,034	$	778,143
Restricted cash		3,519		2,712
Trade accounts receivable and unbilled services, net		1,032,553		924,205
Prepaid expenses		51,534		42,801
Deferred income taxes		94,175		92,115
Income taxes receivable		17,394		16,171
Other current assets and receivables		94,394		89,541
Total current assets		1,938,603		1,945,688
Property and equipment, net		190,863		199,578
Investments in debt, equity and other securities		33,723		40,349
Investments in and advances to unconsolidated affiliates		34,737		22,927
Goodwill		468,620		409,626
Other identifiable intangibles, net		288,266		298,054
Deferred income taxes		31,278		32,864
Deposits and other assets		120,625		117,711
Total assets	$	3,106,715	$	3,066,797
LIABILITIES AND SHAREHOLDERS’ DEFICIT
Current liabilities:
Accounts payable and accrued expenses	$	830,388	$	861,805
Unearned income		526,000		538,585
Income taxes payable		19,219		35,778
Current portion of long-term debt and obligations held under capital leases		20,681		10,433
Other current liabilities		30,492		35,646
Total current liabilities		1,426,780		1,482,247
Long-term debt and obligations held under capital leases, less current portion		2,022,595		2,035,586
Deferred income taxes		25,578		37,541
Other liabilities		167,994		178,908
Total liabilities		3,642,947		3,734,282
Commitments and contingencies
Shareholders’ deficit:
Common stock and additional paid-in capital, 300,000 shares authorized, $0.01 par value, 127,696 and 129,652 shares issued and outstanding at September 30, 2014 and December 31, 2013, respectively		368,010		478,144
Accumulated deficit		(877,224)		(1,145,181)
Accumulated other comprehensive loss		(27,045)		(376)
Deficit attributable to Quintiles Transnational Holdings Inc.’s shareholders		(536,259)		(667,413)
Deficit attributable to noncontrolling interests		27		(72)
Total shareholders’ deficit		(536,232)		(667,485)
Total liabilities and shareholders’ deficit	$	3,106,715	$	3,066,797

The accompanying notes are an integral part of these condensed consolidated financial statements.

5

QUINTILES TRANSNATIONAL HOLDINGS INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(unaudited)

	Nine Months Ended September 30,
	2014		2013
	(in thousands)
Operating activities:
Net income	$	268,057	$	153,093
Adjustments to reconcile net income to cash provided by operating activities:
Depreciation and amortization		89,113		76,950
Amortization of debt issuance costs and discount		4,787		16,944
Share-based compensation		22,388		16,960
(Earnings) loss from unconsolidated affiliates		(9,763)		1,454
Gain on investments, net		(4,806)		(62)
Benefit from deferred income taxes		(11,529)		(15,883)
Excess income tax benefits from share-based award activities		(12,802)		(145)
Changes in operating assets and liabilities:
Change in accounts receivable, unbilled services and unearned income		(118,721)		(74,533)
Change in other operating assets and liabilities		(50,927)		3,133
Net cash provided by operating activities		175,797		177,911
Investing activities:
Acquisition of property, equipment and software		(57,782)		(73,940)
Acquisition of businesses, net of cash acquired		(92,201)		(144,970)
Proceeds from sale of equity securities		5,861		60
Investments in and advances to unconsolidated affiliates, net of payments received		(2,137)		(5,944)
Other		332		802
Net cash used in investing activities		(145,927)		(223,992)
Financing activities:
Repayment of debt and principal payments on capital lease obligations		(6,729)		(385,807)
Issuance of common stock, net of costs		(105)		489,560
Stock issued under employee stock purchase and option plans		23,201		364
Repurchase of common stock		(165,131)		—
Payroll taxes remitted on repurchase of stock options		(8,415)		—
Excess income tax benefits from share-based award activities		12,802		145
Net cash (used in) provided by financing activities		(144,377)		104,262
Effect of foreign currency exchange rate changes on cash		(18,602)		(16,199)
(Decrease) increase in cash and cash equivalents		(133,109)		41,982
Cash and cash equivalents at beginning of period		778,143		567,728
Cash and cash equivalents at end of period	$	645,034	$	609,710

The accompanying notes are an integral part of these condensed consolidated financial statements.

6

QUINTILES TRANSNATIONAL HOLDINGS INC. AND SUBSIDIARIES

Notes to Condensed Consolidated Financial Statements

(unaudited)

1. Basis of Presentation

Unaudited Interim Financial Information

The accompanying unaudited condensed consolidated financial statements of Quintiles Transnational Holdings Inc. and its subsidiaries (the “Company”) have been prepared in accordance with generally accepted accounting principles in the United States of America (“GAAP”) for interim financial information. Accordingly, they do not include all of the information and notes required by GAAP for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring adjustments) considered necessary for a fair statement of the Company’s financial condition and results of operations have been included. Operating results for the periods presented are not necessarily indicative of the results that may be expected for the year ending December 31, 2014. As such, the information included in this quarterly report on Form 10-Q should be read in conjunction with the Company’s audited consolidated financial statements included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2013. The balance sheet at December 31, 2013 has been derived from the audited consolidated financial statements of the Company but does not include all the disclosures required by GAAP.

Reclassifications

Certain immaterial prior period amounts have been reclassified to conform to current period presentation. These changes had no effect on previously reported total revenues, net income, comprehensive income or shareholders’ deficit.

Recently Issued Accounting Standards

In May 2014, the United States Financial Accounting Standards Board and the International Accounting Standards Board issued a converged standard on the recognition of revenue from contracts with customers. The objective of the new standard is to establish a single comprehensive revenue recognition model that is designed to create greater comparability of financial statements across industries and jurisdictions. Under the new standard, companies will recognize revenue to depict the transfer of goods or services to customers in amounts that reflect the consideration to which the company expects to be entitled in exchange for those goods or services. The new standard also will require expanded disclosures on revenue recognition and changes in assets and liabilities that result from contracts with customers. The Company will adopt the new standard on January 1, 2017, as required. Early adoption is not permitted. The Company is currently evaluating the impact of this new standard on its consolidated financial statements.

2. Employee Stock Compensation

The Company granted the following share-based awards:

	Three Months Ended September 30,		Nine Months Ended September 30,
	2013		2014		2013
Stock options		100,000		1,359,600		2,200,500
Stock appreciation rights		10,000		176,800		162,600
Restricted stock units		—		36,500		—

No share-based awards were granted during the three months ended September 30, 2014.

The Company had the following share-based awards outstanding:

	September 30, 2014		December 31, 2013
Stock options		9,811,235		10,100,160
Stock appreciation rights		411,363		258,025
Restricted stock units		93,667		57,167

7

The Company used the following assumptions when estimating the value of the share-based compensation for stock options and stock appreciation rights issued as follows:

	Three Months Ended September 30,	Nine Months Ended September 30,
	2013	2014	2013
Expected volatility	22 –  44%	31 –  43%	18 –  47%
Weighted average expected volatility	33%	37%	40%
Expected dividends	0.0%	0.0%	0.0  –  5.45%
Expected term (in years)	0.25 –  6.4	3.7 – 6.7	0.25  –  6.4
Risk-free interest rate	0.04 – 2.08%	0.99 – 2.21%	0.04 –  2.08%

In November 2013, the Company’s Board of Directors (the “Board”) approved an Employee Stock Purchase Plan (“ESPP”) which was approved by the Company’s shareholders in May 2014. The ESPP allows eligible employees to authorize payroll deductions of up to 10% of their base salary to be applied toward the purchase of full shares of the Company’s common stock on the last day of the offering period. Offering periods under the ESPP are six months in duration and begin on each March 1 and September 1. The first offering period for the ESPP began March 1, 2014. Participating employees will purchase shares on the last day of each offering period at a discount of 15% of the closing price of the common stock on such date as reported on the New York Stock Exchange (“NYSE”). During the three and nine months ended September 30, 2014, the Company issued 46,032 shares of common stock for purchases under the ESPP.

The Company recognized share-based compensation expense of $6.8 million and $5.9 million during the three months ended September 30, 2014 and 2013, respectively, and $22.4 million and $17.0 million during the nine months ended September 30, 2014 and 2013, respectively.

3. Concentration of Credit Risk

No customer accounted for 10% or more of consolidated service revenues for the three and nine months ended September 30, 2014 or 2013.

4. Accounts Receivable and Unbilled Services

Accounts receivable and unbilled services consist of the following (in thousands):

	September 30, 2014			December 31, 2013
Trade:
Billed	$	474,717		$	408,959
Unbilled services		559,848			516,942
		1,034,565			925,901
Allowance for doubtful accounts		(2,012	)		(1,696	)
	$	1,032,553		$	924,205

5. Goodwill

The following is a summary of goodwill by segment for the nine months ended September 30, 2014 (in thousands):

	Product Development		Integrated Healthcare Services		Consolidated
Balance as of December 31, 2013	$	351,144	$	58,482	$	409,626
Acquisition		—		62,778		62,778
Impact of foreign currency fluctuations and other		(2,623)		(1,161)		(3,784)
Balance as of September 30, 2014	$	348,521	$	120,099	$	468,620

6. Derivatives

As of September 30, 2014, the Company held the following derivative positions: (i) freestanding warrants to purchase shares of common stock of third parties, (ii) forward exchange contracts to protect against foreign exchange movements for certain forecasted foreign currency cash flows related to service contracts and (iii) interest rate swaps to hedge the exposure to variability in interest payments on variable interest rate debt. The Company does not use derivative financial instruments for speculative or trading purposes.

8

As of September 30, 2014, the Company had freestanding warrants to purchase shares of third parties’ common stock. No quoted price is available for the warrants. Accordingly, the Company uses various valuation techniques to value the warrants, including the present value of estimated expected future cash flows, option-pricing models and fundamental analysis. Factors affecting the valuation include the current price of the underlying common stock, the exercise price of the warrants, the expected time to exercise the warrants, the estimated price volatility of the underlying common stock over the life of the warrants and the restrictions on the transferability of or ability to exercise the warrants. The Company did not sell any warrants during the three and nine months ended September 30, 2014 or 2013.

As of September 30, 2014, the Company had 12 open foreign exchange forward contracts to hedge certain forecasted foreign currency cash flow transactions occurring in 2014 and the first six months of 2015 with notional amounts totaling $75.6 million. As these contracts were executed to hedge the risk of the potential volatility in the cash flows resulting from fluctuations in currency exchange rates during the remainder of 2014 and the first six months of 2015, these transactions are accounted for as cash flow hedges. As such, the effective portion of the gain or loss on the contracts is recorded as unrealized gains (losses) on derivatives included in the accumulated other comprehensive income (loss) (“AOCI”) component of shareholders’ deficit. These hedges are highly effective. Upon expiration of the hedge instruments in 2014 and the first six months of 2015, the Company will reclassify the unrealized holding gains and losses on the derivative instruments included in AOCI into earnings.

On June 9, 2011, the Company entered into six interest rate swaps effective September 28, 2012 and expiring between September 30, 2013 and March 31, 2016 in an effort to limit its exposure to changes in the variable interest rate on its senior secured credit facilities. The critical terms of the interest rate swaps were substantially the same as those of the Company’s senior secured credit facilities, including quarterly interest settlements. These interest rate swaps are being accounted for as cash flow hedges as these transactions were executed to hedge the Company’s interest payments, and these hedges are highly effective. As such, changes in the fair value of these derivative instruments are recorded as unrealized gains (losses) on derivatives included in the AOCI component of shareholders’ deficit. The fair value of these interest rate swaps represents the present value of the anticipated net payments the Company will make to the counterparty, which, when they occur, are reflected as interest expense on the condensed consolidated statements of income. These payments, together with the variable rate of interest incurred on the underlying debt, result in a fixed rate of interest of 2.57% plus the applicable margin on the affected borrowings ($910.0 million or 44.3% of the Company’s variable rate debt at September 30, 2014). The Company expects that $12.2 million of unrealized losses will be reclassified out of AOCI and will form the interest rate swap component of the 2.57% fixed rate of interest to be incurred over the next 12 months as the underlying net payments are settled.

The fair values of the Company’s derivative instruments designated as hedging instruments and the line items on the accompanying condensed consolidated balance sheets to which they were recorded are summarized in the following table (in thousands):

	Balance Sheet Classification	September 30, 2014		December 31, 2013
Foreign exchange forward contracts	Other current assets	$	—	$	3,950
Foreign exchange forward contracts	Other current liabilities	$	2,410	$	—
Interest rate swaps	Other current liabilities	$	17,185	$	24,805

The fair values of the Company’s derivative instruments not designated as hedging instruments and the line items on the accompanying condensed consolidated balance sheets to which they were recorded are summarized in the following table (in thousands):

	Balance Sheet Classification	September 30, 2014	December 31, 2013
Warrants	Deposits and other assets	$              13	$              211

The effect of the Company’s cash flow hedging instruments on other comprehensive income (loss) is summarized in the following table (in thousands):

	Three Months Ended September 30,					Nine Months Ended September 30,
	2014			2013		2014			2013
Foreign exchange forward contracts	$	(5,216	)	$	4,273	$	(6,360	)	$	2,648
Interest rate swaps		3,308			1,381		7,620			6,838
Total	$	(1,908	)	$	5,654	$	1,260		$	9,486

9

7. Fair Value Measurements

The Company records certain assets and liabilities at fair value. Fair value is defined as the price that would be received to sell an asset or paid to transfer a liability in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants at the measurement date. A three-level fair value hierarchy that prioritizes the inputs used to measure fair value is described below. This hierarchy requires entities to maximize the use of observable inputs and minimize the use of unobservable inputs. The three levels of inputs used to measure fair value are as follows:

• Level 1 — Quoted prices in active markets for identical assets or liabilities.

• Level 2 — Observable inputs other than quoted prices included in Level 1, such as quoted prices for similar assets and liabilities in active markets; quoted prices for identical or similar assets and liabilities in markets that are not active; or other inputs that are observable or can be corroborated by observable market data.

• Level 3 — Unobservable inputs that are supported by little or no market activity. This includes certain pricing models, discounted cash flow methodologies and similar techniques that use significant unobservable inputs.

Recurring Fair Value Measurements

The following table summarizes the fair value of the Company’s financial assets and liabilities that are measured on a recurring basis as of September 30, 2014 (in thousands):

	Level 1		Level 2		Level 3		Total
Assets:
Marketable equity securities	$	1,045	$	—	$	—	$	1,045
Warrants		—		—		13		13
Total	$	1,045	$	—	$	13	$	1,058
Liabilities:
Foreign exchange forward contracts	$	—	$	2,410	$	—	$	2,410
Interest rate swaps		—		17,185		—		17,185
Contingent consideration		—		—		4,443		4,443
Total	$	—	$	19,595	$	4,443	$	24,038

Below is a summary of the valuation techniques used in determining fair value:

Marketable equity securities — The Company values marketable equity securities utilizing quoted market prices.

Foreign exchange forward contracts — The Company values foreign exchange forward contracts using quoted market prices for identical instruments in less active markets or using other observable inputs.

Warrants — The Company values warrants utilizing the Black-Scholes-Merton model.

Interest rate swaps — The Company values interest rate swaps using market inputs with mid-market pricing as a practical expedient for bid-ask spread.

Contingent consideration — The Company values contingent consideration related to business combinations using a weighted probability calculation of potential payment scenarios discounted at rates reflective of the risks associated with the expected future cash flows. Key assumptions used to estimate the fair value of contingent consideration include revenue, net new business and operating forecasts and the probability of achieving the specific targets.

The following table summarizes the changes in Level 3 financial assets and liabilities measured on a recurring basis for the nine months ended September 30 (in thousands):

	Warrants–Deposits and Other Assets				Contingent Consideration – Accounts Payable and Accrued Expenses and Other Liabilities
	2014		2013		2014		2013
Balance as of January 1	$	211	$	29	$	13,014	$	3,521
Initial estimate of contingent consideration		—		—		—		14,300
Revaluations included in earnings		(198)		62		(8,571)		(1,352)
Balance as of September 30	$	13	$	91	$	4,443	$	16,469

10

The revaluations for the warrants and the contingent consideration are recognized in other (income) expense, net on the accompanying condensed consolidated statements of income.

Non-recurring Fair Value Measurements

Certain assets are carried on the accompanying condensed consolidated balance sheets at cost and are not remeasured to fair value on a recurring basis. These assets include cost and equity method investments and loans that are written down to fair value for declines which are deemed to be other-than-temporary, and goodwill and identifiable intangible assets which are tested for impairment annually and when a triggering event occurs.

As of September 30, 2014, assets carried on the balance sheet and not remeasured to fair value on a recurring basis totaling approximately $824.3 million were identified as Level 3. These assets are comprised of cost and equity method investments of $67.4 million, goodwill of $468.6 million and other identifiable intangibles, net of $288.3 million.

The Company has unfunded cash commitments totaling approximately $27.4 million related to its cost and equity method investments as of September 30, 2014.

Goodwill — Goodwill represents the difference between the purchase price and the fair value of the identifiable tangible and intangible net assets resulting from business combinations. The Company performs a qualitative analysis to determine whether it is more likely than not that the estimated fair value of a reporting unit is less than its book value. This includes a qualitative analysis of macroeconomic conditions, industry and market considerations, internal cost factors, financial performance, fair value history and other company specific events. If this qualitative analysis indicates that it is more likely than not that the estimated fair value is less than the book value for the respective reporting unit, the Company applies a two-step impairment test in which the Company determines whether the estimated fair value of the reporting unit is in excess of its carrying value. If the carrying value of the net assets assigned to the reporting unit exceeds the estimated fair value of the reporting unit, the Company performs the second step of the impairment test to determine the implied estimated fair value of the reporting unit’s goodwill. The Company determines the implied estimated fair value of goodwill by determining the present value of the estimated future cash flows for each reporting unit and comparing the reporting unit’s risk profile and growth prospects to selected, reasonably similar publicly traded companies. No indication of impairment was identified during the Company’s annual review.

Indefinite-lived Intangible Asset — The Company performs a qualitative analysis to determine whether it is more likely than not that the estimated fair value of the indefinite-lived intangible asset is less than its carrying value. If this qualitative analysis indicates that it is more likely than not that the estimated fair value is less than the carrying value of the indefinite-lived intangible asset, the Company determines the estimated fair value of the indefinite-lived intangible asset (trade name) by determining the present value of the estimated royalty payments on an after-tax basis that it would be required to pay the owner for the right to use such trade name. If the carrying amount exceeds the estimated fair value, an impairment loss is recognized in an amount equal to the excess. No indication of impairment was identified during the Company’s annual review.

Other

The estimated fair value of the Company’s long-term debt, which is primarily based on rates in which the debt is traded among banks, was approximately $2.0 billion and $2.1 billion at September 30, 2014 and December 31, 2013, respectively.

8. Shareholders’ Deficit

Equity Repurchase Program

On October 30, 2013, the Board approved an equity repurchase program (the “Repurchase Program”) authorizing the repurchase of up to $125.0 million of either the Company’s common stock or vested in-the-money employee stock options, or a combination thereof. The Company repurchased 300 shares of its common stock for $47.51 per share for an aggregate purchase price of approximately $14,000 during the nine months ended September 30, 2014 under the Repurchase Program. As of September 30, 2014, the Company has remaining authorization under the Repurchase Program to repurchase up to $59.5 million of its common stock. The Repurchase Program for vested in-the-money employee stock options expired in November 2013. The Repurchase Program for common stock does not have an end date.

11

Private Share Repurchase

On May 28, 2014, the Company completed the repurchase of 3,287,209 shares of its common stock for $50.23 per share from TPG Quintiles Holdco, L.P., one of its existing shareholders, in a private transaction for an aggregate purchase price of approximately $165.1 million. The repurchase price per share of common stock was equal to 98% of the closing market price of the Company’s common stock on the NYSE on May 27, 2014 (which was $51.26). The repurchase of shares from its existing shareholder was authorized in compliance with the Company’s related party transactions approval policy. The Company funded this private repurchase transaction with cash on hand. This private repurchase transaction was separate from and in addition to the Repurchase Program.

9. Business Combinations

On July 1, 2014, the Company completed the acquisition of Encore Health Resources, LLC (“Encore”) effected through a merger for approximately $91.5 million in cash (net of approximately $2.2 million of acquired cash). Encore has operations in the United States and its business is primarily focused on providing electronic health records (“EHR”) implementation and advisory services to healthcare providers. As part of its Integrated Healthcare Services segment, the Company expects that Encore will enhance its EHR expertise.

This acquisition was a business combination and, accordingly, the assets acquired and the liabilities assumed have been recorded at their respective estimated fair values as of the acquisition date. In connection with the Encore acquisition, the Company recorded goodwill, primarily attributable to the assembled workforce of Encore and expected synergies, which was assigned to the Integrated Healthcare Services segment and is deductible for income tax purposes. The pro forma results of Encore and the acquisition-related expenses are immaterial for separate disclosure. The Company is continuing to evaluate the initial fair value measurement of assets acquired and liabilities assumed as of the acquisition date. Further adjustments may be necessary as additional information related to the fair values of assets acquired and liabilities assumed is assessed during the measurement period (up to one year from the acquisition date). The following table summarizes the preliminary fair value of the net assets acquired of Encore at the date of the acquisition (in thousands):

Assets acquired:

Cash and cash equivalents	$	2,223
Accounts receivable and unbilled services		17,714
Other current assets		443
Property and equipment		289
Goodwill		62,778
Other identifiable intangibles		14,150
Deferred income tax asset – long-term		396
Liabilities assumed:
Accounts payable and accrued expenses		(4,206	)
Other		(31	)
Net assets acquired	$	93,756

The identifiable definite-lived intangible assets consisted of the following:

Other identifiable intangibles (in thousands)
Customer relationships	$	8,800
Acquired backlog		800
Trade names		1,100
Non-compete agreements		450
Software		3,000
Total other identifiable intangibles	$	14,150
Amortized over a weighted average useful life (in years)		8

10. Restructuring

In 2014, the Board approved restructuring plans of approximately $13 million to better align resources with the Company’s strategic direction. These actions are expected to occur throughout 2014 and are expected to result in severance for approximately 350 positions. Through September 30, 2014, the Company has recognized approximately $3.9 million and $700,000 of restructuring costs related to these plans for activities in the Product Development and Integrated Healthcare Services segments, respectively. All of the restructuring costs are related to severance costs. Restructuring costs are not allocated to the Company’s reportable segments as they are not part of the segment performance measures regularly reviewed by management.

12

The following amounts were recorded for the February 2014 restructuring plan and the restructuring plans initiated in prior years (in thousands):

	Severance and Related Costs			Exit Costs			Total
Balance at December 31, 2013	$	5,276		$	198		$	5,474
Expense, net of reversals		3,749			—			3,749
Payments		(5,476	)		(119	)		(5,595	)
Foreign currency translation		(142	)		—			(142	)
Balance at September 30, 2014	$	3,407		$	79		$	3,486

The Company expects the majority of the restructuring accruals at September 30, 2014 will be paid in 2014.

11. Employee Benefit Plans

Defined Benefit Plans

The following table summarizes the components of pension expense related to the Company’s defined benefit plans (in thousands):

	Three Months Ended September 30,						Nine Months Ended September 30,
	2014			2013			2014			2013
Service cost	$	3,275		$	2,916		$	9,953		$	9,050
Interest cost		991			912			2,981			2,770
Expected return on plan assets		(935	)		(705	)		(2,805	)		(2,083	)
Amortization of prior service costs		20			83			60			255
Amortization of actuarial losses		167			169			512			513
	$	3,518		$	3,375		$	10,701		$	10,505

Other

As of September 30, 2014 and December 31, 2013, the Company has a severance accrual included in accounts payable and accrued expenses on the accompanying condensed consolidated balance sheets of $7.5 million and $14.1 million, respectively. The Company recognizes obligations associated with severance related to contractual termination benefits at fair value on the date that it is probable that the affected employees will be entitled to the benefit and the amount can reasonably be estimated. The severance accrual is related to cost reduction programs that will result in severance for approximately 270 positions, which are expected to lower operating costs and improve profitability by reducing excess capacity. These actions are expected to occur and be paid during 2014 and 2015. During the first nine months of 2014, the Company has recognized approximately $2.1 million of net reversals related to these cost reduction programs, primarily as a result of affected individuals transferring into other positions within the Company. Of the $2.1 million decrease from net reversals recognized for these cost reduction programs, approximately ($2.2) million, $105,000 and ($47,000) were related to activities in the Product Development segment, Integrated Healthcare Services segment and corporate activities, respectively.

The following amounts were recorded for the severance associated with cost reduction programs (in thousands):

Balance at December 31, 2013	$	14,056
Expense, net of reversals		(2,111	)
Payments		(4,418	)
Foreign currency translation		(33	)
Balance at September 30, 2014	$	7,494

12. Income Taxes

Due to the potential for expiration of various federal, state, and foreign statutes of limitation, the Company’s unrecognized income tax benefits may change within the next 12 months by a range of zero to $16.6 million.

13

13. Comprehensive Income

Below is a summary of the components of AOCI (in thousands):

	Foreign Currency Translation		Marketable Securities		Derivative Instruments		Defined Benefit Plans		Income Taxes		AOCI
Balance at December 31, 2013	$	(5,829)	$	5,708	$	(20,855)	$	(5,044)	$	25,644	$	(376)
Other comprehensive (loss) income before reclassifications		(24,523)		(763)		(3,301)		—		2,692		(25,895)
Reclassification adjustments		—		(5,004)		4,561		572		(903)		(774)
Balance at September 30, 2014	$	(30,352)	$	(59)	$	(19,595)	$	(4,472)	$	27,433	$	(27,045)

Below is a summary of the (gains) losses reclassified from AOCI into the condensed consolidated statements of income and the affected financial statement line item (in thousands):

Reclassification Adjustments	Affected Financial Statement Line Item	Three Months Ended September 30,				Nine Months Ended September 30,
		2014		2013		2014		2013
Marketable securities:
Marketable securities	Other (income) expense, net	$	—	$	—	$	(5,004)	$	—
Total before income taxes			—		—		(5,004)		—
Income tax expense			—		—		(1,927)		—
Total net of income taxes		$	—	$	—	$	(3,077)	$	—
Derivative instruments:
Interest rate swaps	Interest expense	$	3,149	$	3,248	$	9,344	$	9,433
Foreign exchange forward contracts	Service revenues		(614)		121		(4,783)		1,442
Total before income taxes			2,535		3,369		4,561		10,875
Income tax benefit			1,086		1,285		2,616		3,973
Total net of income taxes		$	1,449	$	2,084	$	1,945	$	6,902
Defined benefit plans:
Amortization of prior service costs	See Note 11	$	20	$	83	$	60	$	255
Amortization of actuarial losses	See Note 11		167		169		512		513
Total before income taxes			187		252		572		768
Income tax benefit			70		95		214		290
Total net of income taxes		$	117	$	157	$	358	$	478

14. Segments

The following table presents the Company’s operations by reportable segment. The Company is managed through two reportable segments, Product Development and Integrated Healthcare Services. Product Development, which primarily serves biopharmaceutical customers engaged in research and development, provides clinical research and clinical trial services. Integrated Healthcare Services provides commercialization services to biopharmaceutical customers and research, analytics, real-world and late phase research, and other services to both biopharmaceutical customers and the broader healthcare market.

14

Certain costs are not allocated to the Company’s segments and are reported as general corporate and unallocated expenses. These costs primarily consist of share-based compensation and expenses for corporate overhead functions such as finance, human resources, information technology, facilities and legal, as well as certain expenses incurred during the second quarter of 2013, including the $25.0 million fee incurred in connection with the termination of the management agreement with affiliates of certain shareholders and the $1.5 million fee paid in connection with the modification of an agreement for the business usage of an airplane owned by GF Management Company, LLC, a company owned by the Company’s Executive Chairman. The Company does not allocate restructuring or impairment charges to its segments. Information presented below is in thousands:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
Service revenues
Product Development	$	771,361	$	714,244	$	2,323,376	$	2,144,721
Integrated Healthcare Services		289,652		218,483		778,401		659,679
Total service revenues		1,061,013		932,727		3,101,777		2,804,400
Costs of revenue, service costs
Product Development		458,731		426,094		1,374,492		1,296,996
Integrated Healthcare Services		232,320		174,600		634,795		532,473
Total costs of revenue, service costs		691,051		600,694		2,009,287		1,829,469
Selling, general and administrative
Product Development		154,460		147,534		471,697		438,341
Integrated Healthcare Services		37,447		32,221		103,069		96,792
General corporate and unallocated		27,120		19,818		82,517		92,580
Total selling, general and administrative		219,027		199,573		657,283		627,713
Income from operations
Product Development		158,170		140,616		477,187		409,384
Integrated Healthcare Services		19,885		11,662		40,537		30,414
General corporate and unallocated		(27,120)		(19,818)		(82,517)		(92,580)
Restructuring costs		(1,793)		(7,201)		(3,749)		(11,897)
Total income from operations.	$	149,142	$	125,259	$	431,458	$	335,321
	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
Depreciation and amortization expense
Product Development	$	23,106	$	20,853	$	69,867	$	57,901
Integrated Healthcare Services		5,803		5,077		15,548		15,697
General corporate and unallocated		1,271		1,394		3,698		3,352
Total depreciation and amortization expense	$	30,180	$	27,324	$	89,113	$	76,950

15. Earnings Per Share

The following table shows the weighted average number of outstanding share-based awards not included in the computation of diluted earnings per share as the effect of including such share-based awards in the computation would be anti-dilutive (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
Weighted average shares subject to anti-dilutive share-based awards		1,324		2,057		1,229		1,635

Share-based awards will have a dilutive effect under the treasury method only when the respective period’s average market value of the Company’s common stock exceeds the exercise proceeds.

15

Item 2.    Management’s Discussion and Analysis of Financial Condition and Results of Operations

Cautionary Statement for Forward-Looking Information

You should read the following discussion and analysis of our financial condition and results of operations in conjunction with our condensed consolidated financial statements and the notes thereto included elsewhere in this Quarterly Report on Form 10-Q and with our audited consolidated financial statements and the notes thereto included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2013.

In addition to historical condensed consolidated financial information, the following discussion contains forward-looking statements that reflect, among other things, our current expectations and anticipated results of operations, all of which are subject to known and unknown risks, uncertainties and other factors that may cause our actual results, performance or achievements, market trends, or industry results to differ materially from those expressed or implied by such forward-looking statements. Therefore, any statements contained herein that are not statements of historical fact may be forward-looking statements and should be evaluated as such. Without limiting the foregoing, the words “anticipates,” “believes,” “estimates,” “expects,” “intends,” “may,” “plans,” “projects,” “should,” “targets,” “will” and the negative thereof and similar words and expressions are intended to identify forward-looking statements. We assume no obligation to update any such forward-looking information to reflect actual results or changes in the factors affecting such forward-looking information.

We caution you that any such forward-looking statements are further qualified by important factors that could cause our actual operating results to differ materially from those in the forward-looking statements, including without limitation, that most of our contracts may be terminated on short notice, and we may be unable to maintain large customer contracts or to enter into new contracts; our financial results may be adversely affected if we underprice our contracts, overrun our cost estimates or fail to receive approval for or experience delays in documenting change orders; the historical indications of the relationship of our backlog to revenues may not be indicative of their future relationship; we may be unable to maintain our information systems or effectively update them; customer or therapeutic concentration could harm our business; our business is subject to risks associated with international operations, including economic, political and other risks, such as compliance with a myriad of laws and regulations, complications from conducting clinical trials in multiple countries simultaneously and changes in exchange rates; the market for our services may not grow as we expect; government regulators or our customers may limit the scope of prescription or withdraw products from the market, and government regulators may impose new regulatory requirements or may adopt new regulations affecting the biopharmaceutical industry; we may be unable to successfully develop and market new services or enter new markets; our failure to perform services in accordance with contractual requirements, regulatory standards and ethical considerations may subject us to significant costs or liability, which could also damage our reputation and cause us to lose existing business or not receive new business; our services are related to treatment of human patients, and we could face liability if a patient is harmed; we may be unable to successfully identify, acquire and integrate businesses, services and technologies; and we have substantial indebtedness and may incur additional indebtedness in the future, which could adversely affect our financial condition. For a further discussion of the risks relating to our business, see “Risk Factors” in our Annual Report on Form 10-K for the fiscal year ended December 31, 2013.

Overview

We are the world’s largest provider of biopharmaceutical development services and commercial outsourcing services. We are positioned at the intersection of business services and healthcare and conduct business in approximately 100 countries with approximately 32,100 employees. We use the breadth and depth of our service offerings, our global footprint and our therapeutic, scientific and analytics expertise to help our biopharmaceutical customers, as well as other healthcare customers, to be more successful in an increasingly complex healthcare environment. Our business is currently organized in two reportable segments, Product Development and Integrated Healthcare Services.

For the three months ended September 30, 2014, our service revenues increased $128.3 million, or 13.8%, at actual foreign exchange rates compared to the same period last year. Our growth in service revenues, excluding the impact of foreign currency fluctuations (“constant currency”), was 14.0%, with 7.9% growth in the Product Development segment and 33.9% growth in the Integrated Healthcare Services segment. For the nine months ended September 30, 2014, our service revenues increased $297.4 million, or 10.6%, to $3.1 billion at actual foreign exchange rates compared to the same period last year. The year to date growth in service revenues on a constant currency basis was 10.3%, with 7.7% growth in the Product Development segment and 18.9% growth in the Integrated Healthcare Services segment.

Income from operations was $149.1 million, net income attributable to Quintiles Transnational Holdings Inc. was $92.7 million and diluted earnings per share was $0.71 for the three months ended September 30, 2014. Income from operations was $431.5 million, net income attributable to Quintiles Transnational Holdings Inc. was $268.0 million and diluted earnings per share was $2.03 for the nine months ended September 30, 2014.

16

Net new business was $1,512 million and $4,014 million for the three and nine months ended September 30, 2014, respectively. This net new business contributed to an ending backlog of $10,746 million at September 30, 2014. “Net new business” and “backlog” are defined under “Net New Business Reporting and Backlog” below.

Product Development

Product Development provides services and expertise that allow biopharmaceutical companies to outsource the clinical development process from first-in-man trials to post-launch monitoring. Our comprehensive service offerings provide the support and functional expertise necessary at each stage of development, as well as the systems and analytical capabilities to help our customers improve product development efficiency and effectiveness. Product Development is comprised of clinical solutions and services and consulting. Clinical solutions and services provides services necessary to develop biopharmaceutical products. These services include project management and clinical monitoring functions for conducting multi-site trials (generally Phase II-IV) (collectively “core clinical”). These also include clinical trial support services that improve clinical trial decision-making, such as global laboratories, data management, biostatistical, safety and pharmacovigilance, early clinical development trials (generally Phase I), and strategic planning and design services, which help improve decisions and performance. We also provide functional services that cover a range of areas. Consulting provides strategy and management consulting services based on life science expertise and advanced analytics, as well as regulatory and compliance consulting services.

Integrated Healthcare Services

Integrated Healthcare Services provides a broad array of services including commercial services, such as providing contract pharmaceutical sales forces in key geographic markets, as well as a growing number of healthcare business services for the broader healthcare sector. Our customized commercialization services are designed to accelerate the commercial success of biopharmaceutical and other health-related products. Service offerings include commercial services (sales representatives, strategy, marketing communications and other areas related to commercialization), real-world and late phase research (drug therapy analysis, real-world research and evidence-based medicine, including research studies to prove a drug’s value), other healthcare services (comparative and cost-effectiveness research capabilities, decision support services, medication adherence and health outcome optimization services, and web-based systems for measuring quality improvement), and electronic health record implementation and advisory services.

On July 1, 2014, we completed the acquisition of Encore Health Resources, LLC, or Encore, for approximately $91.5 million in cash (net of approximately $2.2 million of acquired cash).

Reimbursed Expenses

Reimbursed expenses may fluctuate from period to period due, in part, to where we are in the lifecycle of the many contracts that are in progress at a particular point in time. For instance, these pass-through costs tend to be higher during the early phases of clinical trials as a result of patient recruitment efforts. As reimbursed expenses are pass-through costs to our customers with little to no profit to us, we believe that the fluctuations in reimbursed expenses from period to period are not meaningful to our underlying performance and we do not provide analysis of the fluctuation in these items or their impact on our financial results.

Foreign Currency Fluctuations

The impact from foreign currency fluctuations and constant currency information assumes constant foreign currency exchange rates based on the rates in effect for the comparable prior-year period were used in translation. We believe that providing the impact of fluctuations in foreign currency rates on certain financial results can facilitate analysis of period-to-period comparisons of business performance.

Results of Operations

Backlog and Net New Business

We began 2014 with backlog of $9,855 million, which was 13% higher than at the beginning of 2013. Backlog at September 30, 2014 was $10,746 million.

17

Net new business grew 13% in the third quarter of 2014 to $1,512 million from $1,341 million in third quarter of 2013, driven by growth in Product Development. Product Development’s net new business increased 47% to $1,268 million in the third quarter of 2014 as compared to $862 million for the same period in 2013, led by higher growth in net new business primarily related to the renewal of a five year contract for clinical and data management functional resourcing services as well as net new business generated from the acquisition of Novella Clinical Inc., or Novella, that was completed in the third quarter of 2013. Integrated Healthcare Services’ net new business decreased 49% to $244 million in the third quarter of 2014 as compared to $479 million for the same period in 2013, primarily related to lower contract signings for commercial services in North America and Japan. This decline in contract signings is an example of the fluctuation in our net new business levels from period to period resulting from the receipt of a small number of relatively large orders in any given reporting period. Because of the timing of these large orders, our net new business in that reporting period may reach levels above our historical average and may not be sustained in subsequent reporting periods.

Net new business grew 12% in the first nine months of 2014 to $4,014 million from $3,600 million in the first nine months of 2013, driven by growth in both Product Development and Integrated Healthcare Services. Product Development’s net new business increased 12% to $3,140 million for the first nine months in 2014 as compared to $2,808 million for the same period in 2013, led by higher growth in net new business for functional resourcing business including the renewal of a five year contract for core clinical services and data management services as well as net new business generated from the acquisition of Novella that was completed in the third quarter of 2013. Integrated Healthcare Services’ net new business increased 10% to $874 million in the first nine months of 2014 as compared to $792 million for the same period in 2013, related primarily to growth in commercial services in North America as well as an increase in new business from real-world and late phase research services and net new business from the Encore acquisition.

Service Revenues

	Three Months Ended September 30,				Change
	2014		2013		$		%
	(dollars in millions)
Service revenues	$	1,061.0	$	932.7	$	128.3		13.8	%

For the three months ended September 30, 2014, our service revenues increased $128.3 million, or 13.8%, as compared to the same period in 2013. This increase is comprised of constant currency service revenue growth of approximately $130.2 million, or 14.0%, and a negative impact of approximately $1.9 million from the effects of foreign currency fluctuations. The constant currency service revenue growth, which includes the impact from the Novella and Encore acquisitions, is comprised of a $56.3 million increase in Product Development and a $73.9 million increase in Integrated Healthcare Services.

	Nine Months Ended September 30,				Change
	2014		2013		$		%
	(dollars in millions)
Service revenues	$	3,101.8	$	2,804.4	$	297.4		10.6	%

For the nine months ended September 30, 2014, our service revenues increased $297.4 million, or 10.6%, as compared to the same period in 2013. This increase is comprised of constant currency service revenue growth of approximately $289.7 million, or 10.3%, and a positive impact of approximately $7.7 million from the effects of foreign currency fluctuations. The constant currency service revenue growth, which includes the impact from the Novella and Encore acquisitions, is comprised of a $165.2 million increase in Product Development and a $124.5 million increase in Integrated Healthcare Services.

Costs of Revenue, Service Costs

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(dollars in millions)
Costs of revenue, service costs	$	691.1	$	600.7	$	2,009.3	$	1,829.5
% of service revenues		65.1%		64.4%		64.8%		65.2%

When compared to the same period in 2013, service costs in the third quarter of 2014 increased $90.4 million. The increase included a constant currency increase in expenses of approximately $93.8 million, or 15.6%, partially offset by a positive impact of approximately $3.4 million from the effects of foreign currency fluctuations. The constant currency service costs growth was due to incremental costs resulting from the Novella and Encore acquisitions and increases in compensation and related expenses due to annual merit increases and an increase in billable headcount needed to support our higher volume of revenue. These increases in compensation and related expenses were partially offset by efficiencies gained from restructuring activities taken in prior years.

18

When compared to the same period in 2013, service costs in the first nine months of 2014 increased $179.8 million. The increase included a constant currency increase in expenses of approximately $188.8 million, or 10.3%, partially offset by a positive impact of approximately $9.0 million from the effects of foreign currency fluctuations. The constant currency service costs growth was due to incremental costs resulting from the Novella and Encore acquisitions and increases in compensation and related expenses due to (1) annual merit increases, (2) an increase in billable headcount needed to support our higher volume of revenue and (3) a reduction of an accrual for statutory profit sharing of approximately $5.4 million in 2013 as a result of guidance handed down by an administrative court in France. These increases in compensation and related expenses were partially offset by efficiencies gained from restructuring activities taken in prior years.

Selling, General and Administrative

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(dollars in millions)
Selling, general and administrative	$	219.0	$	199.6	$	657.3	$	627.7
% of service revenues		20.6%		21.4%		21.2%		22.4%

The $19.4 million increase in selling, general and administrative expenses in the third quarter of 2014 included a constant currency increase of $19.0 million, or 9.5%, and an increase of approximately $400,000 from a negative foreign currency impact. The constant currency increase was primarily due to (1) incremental costs from the Novella and Encore acquisitions, (2) an increase in share-based compensation and (3) increases in compensation and related expenses resulting primarily from annual merit increases and an increase in headcount.

The $29.6 million increase in selling, general and administrative expenses in the first nine months of 2014 was due to a constant currency increase of $30.1 million, or 4.8%, partially offset by a decrease of approximately $500,000 from a positive foreign currency impact. The constant currency increase was primarily due to (1) incremental costs from the Novella and Encore acquisitions, (2) an increase in share-based compensation and (3) increases in compensation and related expenses resulting primarily from annual merit increases and an increase in headcount. These increases were partially offset by expenses incurred in the first nine months of 2013 that did not recur in 2014 related to a $25.0 million fee paid in connection with the termination of our management agreement with affiliates of certain of our shareholders and a $1.5 million fee paid in connection with the modification of an agreement for the business usage of an airplane owned by GF Management Company, LLC, or GFM, a company controlled by our Executive Chairman.

Restructuring Costs

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(in millions)
Restructuring costs	$	1.8	$	7.2	$	3.7	$	11.9

In 2014, our Board of Directors, or our Board, approved restructuring plans of approximately $13 million to better align our resources with our strategic direction. We recognized $1.8 million and $3.7 million of restructuring charges, net of reversals for changes in estimates, during the three and nine months ended September 30, 2014, respectively, which was primarily related to the 2014 restructuring plans. These actions are expected to occur throughout 2014 and are expected to result in severance for approximately 350 positions. We believe that this plan will result in annualized cost savings of approximately $20.0 to $25.0 million.

Interest Income and Interest Expense

	Three Months Ended September 30,						Nine Months Ended September 30,
	2014			2013			2014			2013
	(in millions)
Interest income	$	(0.6	)	$	(1.1	)	$	(2.9	)	$	(2.4	)
Interest expense	$	25.1		$	28.8		$	74.6		$	96.7

Interest income includes interest received from bank balances and investments.

19

Interest expense during the three and nine months ended September 30, 2014 was lower than the same periods in 2013 in part due to a decrease in the average rate of interest. The average rate of interest on the term loan under our senior secured credit facility during the three and nine months ended September 30, 2014 was 75 basis points lower than it was during the same periods in 2013 due to a reduction in the interest rate pursuant to the terms and conditions in the credit agreement as well as from the refinancing transaction we completed in the fourth quarter of 2013. In addition to the lower average rate of interest, interest expense during the nine months ended September 30, 2014 also benefited from a decrease in the average debt outstanding as a result of the repayment of the $300.0 million term loan, which Quintiles Transnational Holdings Inc. obtained in February 2012 and paid in full in May 2013, the pay down of $50.0 million of outstanding indebtedness under our senior secured credit facilities in May 2013 and the mandatory prepayment of $33.8 million of outstanding indebtedness under our senior secured credit facilities in the first quarter of 2013.

Loss on Extinguishment of Debt

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(in millions)
Loss on extinguishment of debt	$	—	$	—	$	—	$	16.5

In May 2013, we recognized a $16.5 million loss on extinguishment of debt related to payment of all amounts outstanding under the $300.0 million term loan and a $50.0 million pay down of outstanding indebtedness under our senior secured credit facilities. The loss on extinguishment of debt included approximately $5.6 million of unamortized debt issuance costs, $4.8 million of unamortized discount and $6.1 million of fees and expenses.

Other (Income) Expense, Net

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(in millions)
Other (income) expense, net	$	(7.8)	$	3.2	$	(9.6)	$	1.4

Other (income) expense, net for the third quarter of 2014 includes income of approximately $8.8 million related to the change in fair value of contingent consideration from an acquisition, partially offset by other expenses, primarily consisting of $926,000 of foreign currency net losses. Other (income) expense, net for the nine months of 2014 includes income of approximately $8.6 million related to the change in fair value of contingent consideration from an acquisition as well as a gain from the sale of marketable equity securities of approximately $5.0 million, partially offset by other expenses, primarily consisting of $4.3 million of foreign currency net losses. The three and nine months ended September 30, 2013 included income of approximately $1.2 million and $1.4 million, respectively, due to changes in the estimated fair value of contingent consideration from acquisitions, which was more than offset by other expenses, primarily consisting of $4.3 million and $3.4 million of foreign currency net losses, respectively.

Income Tax Expense

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(dollars in millions)
Income tax expense	$	41.3	$	27.5	$	111.0	$	68.4
Effective income tax rate		31.1%		29.1%		30.1%		30.7%

Due to the potential for expiration of various federal, state, and foreign statutes of limitation, our unrecognized income tax benefits may change within the next 12 months by a range of zero to $16.6 million.

Equity in Earnings (Losses) of Unconsolidated Affiliates

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(in millions)
Equity in earnings (losses) of unconsolidated affiliates	$	1.5	$	(0.4)	$	9.8	$	(1.6)

Equity in earnings (losses) of unconsolidated affiliates for both the three and nine month periods of 2014 increased as compared to the same periods in 2013 primarily due to gains from our investment in the NovaQuest Pharma Opportunities Fund III, L.P.

20

Segments

Service revenues and income from operations by segment are as follows (dollars in millions):

Three Months Ended September 30, 2014 and 2013
	Service Revenues				Income from Operations				Operating Profit Margin
	2014		2013		2014		2013		2014	2013
Product Development	$	771.4	$	714.2	$	158.2	$	140.6	20.5%	19.7%
Integrated Healthcare Services		289.6		218.5		19.9		11.7	6.9	5.3
Total segment		1,061.0		932.7		178.1		152.3	16.8%	16.3%
General corporate and unallocated expenses						(27.2)		(19.8)
Restructuring costs						(1.8)		(7.2)
Consolidated	$	1,061.0	$	932.7	$	149.1	$	125.3

Nine Months Ended September 30, 2014 and 2013
	Service Revenues				Income from Operations				Operating Profit Margin
	2014		2013		2014		2013		2014	2013
Product Development	$	2,323.4	$	2,144.7	$	477.2	$	409.4	20.5%	19.1%
Integrated Healthcare Services		778.4		659.7		40.5		30.4	5.2	4.6
Total segment		3,101.8		2,804.4		517.7		439.8	16.7%	15.7%
General corporate and unallocated expenses						(82.5)		(92.6)
Restructuring costs						(3.7)		(11.9)
Consolidated	$	3,101.8	$	2,804.4	$	431.5	$	335.3

Certain costs are not allocated to our segments and are reported as general corporate and unallocated expenses. These costs primarily consist of share-based compensation and expenses for corporate office functions such as senior leadership, finance, human resources, information technology, or IT, facilities and legal, as well as certain expenses incurred in the second quarter of 2013 including the $25.0 million fee incurred in connection with the termination of the management agreement with affiliates of certain shareholders and the $1.5 million fee paid in connection with the modification of an agreement for the business usage of an airplane owned by GFM. We do not allocate restructuring or impairment charges to our segments.

Product Development

	Three Months Ended September 30,				Change
	2014		2013		$		%
	(dollars in millions)
Service revenues	$	771.4	$	714.2	$	57.2		8.0%
Costs of revenue, service costs		458.7		426.1		32.6		7.7
as a percentage of service revenues		59.5%		59.7%
Selling, general and administrative		154.5		147.5		7.0		4.7
as a percentage of service revenues		20.0%		20.6%
Segment income from operations	$	158.2	$	140.6	$	17.6		12.5%
as a percentage of service revenues		20.5%		19.7%

	Nine Months Ended September 30,				Change
	2014		2013		$		%
	(dollars in millions)
Service revenues	$	2,323.4	$	2,144.7	$	178.7		8.3	%
Costs of revenue, service costs		1,374.5		1,297.0		77.5		6.0
as a percentage of service revenues		59.2%		60.5%
Selling, general and administrative		471.7		438.3		33.4		7.6
as a percentage of service revenues		20.3%		20.4%
Segment income from operations	$	477.2	$	409.4	$	67.8		16.6	%
as a percentage of service revenues		20.5%		19.1%

21

Service Revenues

Product Development’s service revenues were $771.4 million in the third quarter of 2014, an increase of $57.2 million, or 8.0%, over the same period in 2013. This increase was comprised of constant currency service revenue growth of $56.3 million, or 7.9%, and a positive impact of approximately $900,000 from the effects of foreign currency fluctuations. The constant currency service revenue growth was primarily a result of a volume-related increase of $31.0 million as well as $25.3 million from the Novella acquisition.

Product Development’s service revenues were $2,323.4 million in the first nine months of 2014, an increase of $178.7 million, or 8.3%, over the same period in 2013. This increase was comprised of constant currency service revenue growth of 165.2 million, or 7.7%, and a positive impact of approximately $13.5 million from the effects of foreign currency fluctuations. The constant currency service revenue growth was primarily a result of a volume-related increase of $75.6 million as well as $89.6 million from the Novella acquisition.

The volume-related service revenue growth was primarily from clinical solutions and services for both the three and nine month periods and was related to an increase in global laboratories services, clinical trial support services and clinical solutions provided on a functional resource basis. This growth was due largely to execution on the higher backlog in place as we entered the three and nine month periods. The rate of year-over-year revenue growth was negatively impacted by the wind-down of a large clinical solutions project delivered throughout 2013.

Costs of Revenue, Service Costs

Product Development’s service costs increased approximately $32.6 million in the third quarter of 2014 over the same period in 2013. This increase was comprised of a $34.4 million constant currency increase, or 8.1%, partially offset by a reduction of $1.8 million from the positive effect of foreign currency fluctuations. The constant currency service costs growth was due to incremental costs resulting from the Novella acquisition and increases in expenses directly related to our service contracts to support our higher volume of revenue. These increases in service costs were partially offset by efficiencies gained from restructuring activities taken in prior years. As a percent of service revenues, Product Development’s service costs were 59.5% and 59.7% in the third quarters of 2014 and 2013, respectively. The decrease in service costs as a percentage of service revenues was primarily a result of a closer alignment of resources with project requirements (including cost efficiencies gained from restructuring actions taken in prior years).

Product Development’s service costs increased approximately $77.5 million in the first nine months of 2014 over the same period in 2013. This increase was comprised of a $83.5 million constant currency increase, or 6.5%, partially offset by a reduction of $6.0 million from the positive effect of foreign currency fluctuations. The constant currency service costs growth was due to (1) incremental costs resulting from the Novella acquisition, (2) increases in expenses directly related to our service contracts to support our higher volume of revenue, and (3) a reduction of an accrual for statutory profit sharing of approximately $5.4 million in 2013 as a result of guidance handed down by an administrative court in France. These increases in service costs were partially offset by efficiencies gained from restructuring activities taken in prior years. As a percent of service revenues, Product Development’s service costs were 59.2% and 60.5% in the first nine months of 2014 and 2013, respectively. The decrease in service costs as a percentage of service revenues was primarily a result of a closer alignment of resources with project requirements (including cost efficiencies gained from restructuring actions taken in prior years).

Selling, General and Administrative

As a percent of service revenues, Product Development’s selling, general and administrative expenses were 20.0% and 20.6% in the third quarter of 2014 and 2013, respectively. Product Development’s selling, general and administrative expenses increased approximately $7.0 million, or 4.7%, in the third quarter of 2014 as compared to the same period in 2013. This increase was primarily caused by the impact from the Novella acquisition and increases in compensation and related expenses resulting from annual merit increases and an increase in headcount.

As a percent of service revenues, Product Development’s selling, general and administrative expenses were 20.3% and 20.4% in the first nine months of 2014 and 2013, respectively. Product Development’s selling, general and administrative expenses increased approximately $33.4 million, or 7.6%, in the first nine months of 2014 as compared to the same period in 2013. This increase was primarily caused by the impact from the Novella acquisition, increases in compensation and related expenses resulting from annual merit increases and an increase in headcount, and a growth related increase in IT costs partially offset by a positive impact of approximately $1.1 million from the effects of foreign currency fluctuations.

22

Integrated Healthcare Services

	Three Months Ended September 30,				Change
	2014		2013		$		%
	(dollars in millions)
Service revenues	$	289.6	$	218.5	$	71.1		32.6%
Costs of revenue, service costs		232.3		174.6		57.7		33.1
as a percentage of service revenues		80.2%		79.9%
Selling, general and administrative		37.4		32.2		5.2		16.2
as a percentage of service revenues		12.9%		14.8%
Segment income from operations	$	19.9	$	11.7	$	8.2		70.5%
as a percentage of service revenues		6.9%		5.3%

	Nine Months Ended September 30,				Change
	2014		2013		$		%
	(dollars in millions)
Service revenues	$	778.4	$	659.7	$	118.7		18.0%
Costs of revenue, service costs		634.8		532.5		102.3		19.2
as a percentage of service revenues		81.6%		80.7%
Selling, general and administrative		103.1		96.8		6.3		6.5
as a percentage of service revenues		13.2%		14.7%
Segment income from operations	$	40.5	$	30.4	$	10.1		33.3%
as a percentage of service revenues		5.2%		4.6%

Service Revenues

Integrated Healthcare Services’ service revenues were $289.6 million in the third quarter of 2014, an increase of $71.1 million, or 32.6%, over the same period in 2013. This increase is comprised of constant currency service revenue growth of $73.9 million, or 33.9%, including $19.2 million from the Encore acquisition, partially offset by a negative impact of approximately $2.8 million due to the effect of foreign currency fluctuations.

Integrated Healthcare Services’ service revenues were $778.4 million in the first nine months of 2014, an increase of $118.7 million, or 18.0%, over the same period in 2013. This increase is comprised of constant currency service revenue growth of $124.5 million, or 18.9%, including $19.2 million from the Encore acquisition, partially offset by a negative impact of approximately $5.8 million due to the effect of foreign currency fluctuations.

For both the three and nine month periods in 2014, the increase in constant currency service revenues was driven by the impact from the Encore acquisition and an increase in commercial services in North America and Japan, as well as growth in real-world and late phase research services. These increases were partially offset by a decline in Europe due to lower revenue from an agreement to distribute pharmaceutical products in Italy as well as lower commercial services revenues. The agreement to distribute pharmaceutical products in Italy will end in the fourth quarter of 2014.

Costs of Revenue, Service Costs

Integrated Healthcare Services’ service costs increased approximately $57.7 million in the third quarter of 2014. This increase was comprised of a $59.3 million constant currency increase, or 34.0%, partially offset by a reduction of $1.6 million from the positive effect of foreign currency fluctuations.

Integrated Healthcare Services’ service costs increased approximately $102.3 million in the first nine months of 2014. This increase was comprised of a $105.2 million constant currency increase, or 19.8%, partially offset by a reduction of $2.9 million from the positive effect of foreign currency fluctuations.

For both the three and nine month periods in 2014, the constant currency increase was primarily due to the impact from the Encore acquisition and increases in compensation and related expenses resulting from an increase in billable headcount needed to support the higher volume of revenue and annual merit compensation increases. These increases in compensation and related expenses were partially offset by a decline in other expenses directly related to the agreement to distribute pharmaceutical products in Italy. Service costs as a percentage of service revenues were 80.2% and 79.9% in the third quarters of 2014 and 2013, respectively, and 81.6% and 80.7% in the first nine months of 2014 and 2013, respectively. The increase in service costs as a percentage of service revenues was primarily in Europe and reflects the competitive pricing environment for our commercial services in that region.

23

Selling, General and Administrative

Integrated Healthcare Services’ selling, general and administrative expenses in the three and nine months ended September 30, 2014 were higher as compared to the same periods in 2013 primarily caused by the impact from the Encore acquisition and higher compensation and related expenses.

Liquidity and Capital Resources

Overview

We assess our liquidity in terms of our ability to generate cash to fund our operating, investing and financing activities. Our principal source of liquidity is operating cash flows. In addition to operating cash flows, other significant factors that affect our overall management of liquidity include: capital expenditures, acquisitions, debt service requirements, dividends, equity repurchases, adequacy of our revolving credit facility and access to the capital markets.

We manage our worldwide cash requirements by monitoring the funds available among our subsidiaries and determining the extent to which those funds can be accessed on a cost effective basis. The repatriation of cash balances from certain of our subsidiaries could have adverse income tax consequences. During the second quarter of 2013, we changed our assertion regarding the earnings of most of our foreign subsidiaries and now consider them indefinitely reinvested outside of the United States. Making this assertion limits our ability to repatriate cash from our foreign subsidiaries for the foreseeable future. In making this assertion, we determined that the cash flows expected to be generated in the United States should be sufficient to fund our operating requirements and debt service obligations in the United States and that we intend to use the cash generated by the affected foreign subsidiaries to fund growth outside of the United States. A future distribution or change in this assertion could result in additional tax liability.

We had a cash balance of $645.0 million at September 30, 2014 ($203.1 million of which was in the United States), a decrease from $778.1 million at December 31, 2013.

On October 30, 2013, our Board approved an equity repurchase program, or the Repurchase Program, authorizing the repurchase of up to $125.0 million of either our common stock or vested in-the-money employee stock options, or a combination thereof. Through September 30, 2014, we have used $65.5 million of cash to purchase $59.1 million of stock options and $6.4 million of common stock under the Repurchase Program. We have used and intend to continue to use cash on hand to fund the Repurchase Program. The Repurchase Program does not obligate us to repurchase any particular amount of common stock or vested in-the-money employee stock options and it can be modified, suspended or discontinued at any time. Repurchases of vested in-the-money employee stock options were made through transactions between us and our employees (other than our executive officers, who were not eligible to participate in the program) and this aspect of the Repurchase Program expired in November 2013. The Repurchase Program for common stock does not have an end date. Additional information regarding our Repurchase Program is presented in Part II, Item 2 “Unregistered Sales of Equity Securities, Use of Proceeds and Issuer Purchases of Equity Securities” of this Quarterly Report on Form 10-Q.

On May 28, 2014, we completed the repurchase of 3,287,209 shares of our common stock for $50.23 per share from TPG Quintiles Holdco, L.P., one of our existing shareholders, in a private transaction for an aggregate purchase price of approximately $165.1 million. We funded this private repurchase transaction with cash on hand. This private repurchase transaction was separate from and in addition to the Repurchase Program.

On July 1, 2014, we completed the acquisition of Encore for approximately $91.5 million in cash (net of approximately $2.2 million of acquired cash). Encore has operations in the United States and its business is primarily focused on providing electronic health records implementation and advisory services to healthcare providers.

24

Based on our current operating plan, we believe that our available cash and cash equivalents, future cash flows from operations and our ability to access funds under our revolving credit facility, will enable us to fund our operating requirements and capital expenditures and meet debt obligations for at least the next 12 months. We regularly evaluate our debt arrangements, as well as market conditions, and from time to time we may explore opportunities to modify our existing debt arrangements or pursue additional financing arrangements that could result in the issuance of new debt securities by us or our affiliates. We may use our existing cash, cash generated from operations or dispositions of assets or businesses and/or proceeds from any new financing arrangements or issuances of debt or equity securities to repay or reduce some of our outstanding obligations, to repurchase shares from our shareholders or for other purposes. As part of our ongoing business strategy, we also are continually evaluating new acquisition, expansion and investment possibilities or other strategic growth opportunities, as well as potential dispositions of assets or businesses, as appropriate, including dispositions that may cause us to recognize a loss on certain assets. Should we elect to pursue any such transaction, we may seek to obtain debt or equity financing to facilitate those activities. Our ability to enter into any such potential transactions and our use of cash or proceeds is limited to varying degrees by the terms and restrictions contained in our senior secured credit facilities. We cannot provide assurances that we will be able to complete any such alternative financing arrangements or other transactions on favorable terms or at all.

Long-Term Debt

As of September 30, 2014, we had $2.0 billion of total indebtedness. Additionally, our senior secured credit agreement provides for a $300 million revolving credit facility. There were no amounts drawn on this revolving credit facility in the first nine months of 2014. Our long-term debt arrangements contain usual and customary restrictive covenants, and as of September 30, 2014, we believe we were in compliance with these covenants.

See “Management’s Discussion and Analysis – Liquidity and Capital Resources” and Note 10 to our audited consolidated financial statements, each included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2013, for additional details regarding our credit arrangements.

Nine months ended September 30, 2014 and 2013

Cash Flow from Operating Activities

	Nine Months Ended September 30,
	2014		2013
	(in millions)
Net cash provided by operating activities	$	175.8	$	177.9

Cash provided by operating activities decreased by $2.1 million during the first nine months of 2014 as compared to the same period in 2013. The decrease in operating cash flow reflects less cash received from upfront payments under customer contracts in the first nine months of 2014 as compared to the same period in 2013, higher payments for income taxes ($70.5 million), and higher cash used for incentive compensation. These decreases in operating cash flow were partially offset by an increase in net income as well as lower payments for interest ($20.6 million). In addition, net income for the first nine months of 2013 included cash expenses totaling $32.5 million for a fee paid in connection with the termination of our management agreement with affiliates of certain of our shareholders ($25.0 million), a fee paid in connection with the modification of an agreement for the business usage of an airplane owned by GFM ($1.5 million), and a termination fee for the repayment of the $300.0 million term loan ($6.0 million), which did not recur in the 2014 period.

Cash Flow from Investing Activities

	Nine Months Ended September 30,
	2014		2013
	(in millions)
Net cash used in investing activities	$	(145.9)	$	(224.0)

Cash used in investing activities decreased by $78.1 million during the first nine months of 2014 as compared to the same period in 2013. This decline in the use of cash in the first nine months of 2014 was primarily related to lower cash used for the acquisition of businesses. The 2014 period includes approximately $92.2 million primarily for the acquisition of Encore, as compared to the 2013 period which includes the acquisition of Novella for approximately $145.0 million. Also contributing to the decline was lower cash used for property, equipment and software and an increase in proceeds from the sale of equity securities.

25

Cash Flow from Financing Activities

	Nine Months Ended September 30,
	2014		2013
	(in millions)
Net cash (used in) provided by financing activities	$	(144.4)	$	104.3

Net cash used in financing activities increased by $248.7 million to $144.4 million during the first nine months of 2014, as compared to cash provided by financing activities of $104.3 million in the same period in 2013. The cash used in financing activities in the first nine months of 2014 was primarily related to the repurchase of common stock ($165.1 million) partially offset by stock issued under employee stock purchase and option plans ($23.2 million). The cash provided by financing activities in the first nine months of 2013 was primarily related to the net proceeds from our initial public offering, or IPO, in May 2013 ($489.6 million). The net IPO proceeds were partially offset as a result of repayment of all amounts outstanding under the $300.0 million term loan and $83.8 million of repayments on our senior secured credit facilities, which included a voluntary pay down of $50.0 million and a mandatory prepayment of $33.8 million as a result of excess cash flow (as defined in the credit agreement).

Net New Business Reporting and Backlog

Net new business is the value of services awarded during the period from projects under signed contracts, letters of intent and, in some cases, pre-contract commitments, which are supported by written communications and adjusted for contracts that were modified or canceled during the period.

Consistent with our methodology for calculating net new business during a particular period, backlog represents, at a particular point in time, future service revenues from work not yet completed or performed under signed contracts, letters of intent and, in some cases, pre-contract commitments that are supported by written communications. Once work begins on a project, service revenues are recognized over the duration of the project. Included within backlog at September 30, 2014 is approximately $7,193 million of backlog that we do not expect to generate revenue in the next 12 months.

Backlog was as follows:

	September 30, 2014		December 31, 2013
	(in millions)
Backlog	$	10,746	$	9,855

Net new business was as follows:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
	(in millions)
Net new business	$	1,512	$	1,341	$	4,014	$	3,600

Contractual Obligations and Commitments

We have various contractual obligations, which are recorded as liabilities in our consolidated financial statements. Other items, such as operating lease obligations, are not recognized as liabilities in our consolidated financial statements but are required to be disclosed.

There have been no material changes, outside of the ordinary course of business, to our contractual obligations as previously disclosed in our Annual Report on Form 10-K for the fiscal year ended December 31, 2013.

Application of Critical Accounting Policies

There have been no material changes to our critical accounting policies as previously disclosed in our Annual Report on Form 10-K for the fiscal year ended December 31, 2013.

26

Item 3. Quantitative and Qualitative Disclosures About Market Risk

There have been no material changes to our quantitative and qualitative disclosures about market risk as compared to the quantitative and qualitative disclosures about market risk described in our Annual Report on Form 10-K for the fiscal year ended December 31, 2013.

Item 4. Controls and Procedures

Evaluation of Disclosure Controls and Procedures

Our management, with the participation of our Chief Executive Officer, or CEO, and Chief Financial Officer, or CFO, has evaluated the effectiveness of our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended, or the Exchange Act), as of the end of the period covered by this Quarterly Report on Form 10-Q. Based on such evaluation, our CEO and CFO have concluded that as of such date, our disclosure controls and procedures were effective.

In designing and evaluating the disclosure controls and procedures, management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving the desired control objectives. In addition, the design of disclosure controls and procedures must reflect the fact that there are resource constraints and that management is required to apply judgment in evaluating the benefits of possible controls and procedures relative to their costs.

Changes in Internal Control Over Financial Reporting

There were no changes in our internal control over financial reporting identified in management’s evaluation pursuant to Rules 13a-15(d) or 15d-15(d) of the Exchange Act during the period covered by this Quarterly Report on Form 10-Q that materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

PART II—OTHER INFORMATION

Item 1. Legal Proceedings

We are party to legal proceedings incidental to our business. While the outcome of these matters could differ from management’s expectations, we do not believe that the resolution of these matters is reasonably likely to have a material adverse effect to our financial statements.

Item 1A. Risk Factors

For a discussion of our potential risks and uncertainties, see the information under the heading “Risk Factors” in our Annual Report on Form 10-K for the fiscal year ended December 31, 2013. There have been no significant changes from the risk factors previously disclosed in our Annual Report.

Item 2. Unregistered Sales of Equity Securities, Use of Proceeds and Issuer Purchases of Equity Securities

Recent Sales of Unregistered Securities

Not applicable.

Use of Proceeds from Registered Securities

Not applicable.

27

Purchases of Equity Securities by the Issuer

The following table summarizes the Repurchase Program activity for the three months ended September 30, 2014 and the approximate dollar value of shares that may yet be purchased pursuant to the Repurchase Program:

Period	Total Number of Shares Purchased		Average Price Paid per Share		Total Number of Shares Purchased as Part of Publicly Announced Plans or Programs		Approximate Dollar Value of Shares That May Yet Be Purchased Under the Plans or Programs
	(in thousands, except share and per share data)
July 1, 2014 – July 31, 2014		—	$	—		—	$	59,486
August 1, 2014 – August 31, 2014		—	$	—		—	$	59,486
September 1, 2014 – September 30, 2014		—	$	—		—	$	59,486
		—				—

On October 31, 2013, we announced that on October 30, 2013 our Board approved the Repurchase Program, authorizing the repurchase of up to $125.0 million of either our common stock or employee stock options, or a combination thereof. We have used and intend to continue to use cash on hand to fund the Repurchase Program. The Repurchase Program does not obligate us to repurchase any particular amount of common stock or employee stock options, and it could be modified, suspended or discontinued at any time. The timing and amount of repurchases are determined by our management based on a variety of factors such as the market price of our common stock, our corporate requirements, and overall market conditions. Purchases of our common stock may be made in open market transactions effected through a broker-dealer at prevailing market prices, in block trades, or in privately negotiated transactions. We may also repurchase shares of our common stock pursuant to a trading plan meeting the requirements of Rule 10b5-1 under the Exchange Act, which would permit shares of our common stock to be repurchased when we might otherwise be precluded from doing so by law. Repurchases of employee stock options were made through transactions between us and our employees (other than our executive officers, who were not eligible to participate in the program), and this aspect of the Repurchase Program expired in November 2013. The Repurchase Program for common stock does not have an end date.

Item 6. Exhibits

The exhibits in the accompanying Exhibit Index following the signature page are filed or furnished as a part of this report and are incorporated herein by reference.

28

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this Quarterly Report on Form 10-Q to be signed on its behalf by the undersigned, thereunto duly authorized in the City of Durham, State of North Carolina, on October 30, 2014.

QUINTILES TRANSNATIONAL HOLDINGS INC.

/s/ Kevin K. Gordon

Kevin K. Gordon

Executive Vice President and Chief Financial Officer

(On behalf of the Registrant and as Principal Financial Officer)

29

EXHIBIT INDEX

			Incorporated by Reference
Exhibit       Number	Exhibit Description	Filed     Herewith	Form	File No.	Exhibit	Filing Date
31.1	Certification of Chief Executive Officer, pursuant to Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.	X
31.2	Certification of Executive Vice President and Chief Financial Officer, pursuant to Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.	X
32.1	Certification of Chief Executive Officer, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.	X
32.2	Certification of Executive Vice President and Chief Financial Officer, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.	X
101	Interactive Data Files Pursuant to Rule 405 of Regulation S-T: (i) Consolidated Statements of Income, (ii) Consolidated Statements of Comprehensive Income, (iii) Consolidated Balance Sheets, (iv) Consolidated Statements of Cash Flows, and (v) Notes to Consolidated Financial Statements	X

30

EX-31.1

Exhibit 31.1

CERTIFICATION OF PERIODIC REPORT UNDER SECTION 302 OF

THE SARBANES-OXLEY ACT OF 2002

I, Thomas H. Pike, certify that:

1. I have reviewed this quarterly report on Form 10-Q of Quintiles Transnational Holdings Inc. (the “registrant”);

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(c) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5. The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Date: October 30, 2014

/s/ Thomas H. Pike

Thomas H. Pike

Chief Executive Officer

(Principal Executive Officer)

EX-31.2

Exhibit 31.2

CERTIFICATION OF PERIODIC REPORT UNDER SECTION 302 OF

THE SARBANES-OXLEY ACT OF 2002

I, Kevin K. Gordon, certify that:

1. I have reviewed this quarterly report on Form 10-Q of Quintiles Transnational Holdings Inc. (the “registrant”);

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(c) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5. The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Date: October 30, 2014

/s/ Kevin K. Gordon

Kevin K. Gordon

Executive Vice President and Chief Financial Officer

(Principal Financial Officer)

EX-32.1

Exhibit 32.1

CERTIFICATION PURSUANT TO

18 U.S.C. SECTION 1350

AS ADOPTED PURSUANT TO SECTION 906

OF THE SARBANES-OXLEY ACT OF 2002

I, Thomas H. Pike, Chief Executive Officer of Quintiles Transnational Holdings Inc. (the “Company”), do hereby certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that to the best of my knowledge:

(1) the Quarterly Report on Form 10-Q of the Company for the quarter ended September 30, 2014 (the “Report”) fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company for the periods presented therein.

Date: October 30, 2014

/s/ Thomas H. Pike

Thomas H. Pike

Chief Executive Officer

(Principal Executive Officer)

This certification is being furnished solely to accompany the Report pursuant to 18 U.S.C. § 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, and shall not be deemed “filed” by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, and shall not be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended, whether made before or after the date of this Report, irrespective of any general incorporation language contained in such filing.

A signed original of this written statement required by Section 906 of the Sarbanes-Oxley Act of 2002 has been provided to the Company and will be retained by the Company and furnished to the Securities and Exchange Commission or its staff upon request.

EX-32.2

Exhibit 32.2

CERTIFICATION PURSUANT TO

18 U.S.C. SECTION 1350

AS ADOPTED PURSUANT TO SECTION 906

OF THE SARBANES-OXLEY ACT OF 2002

I, Kevin K. Gordon, Executive Vice President and Chief Financial Officer of Quintiles Transnational Holdings Inc. (the “Company”), do hereby certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that to the best of my knowledge:

(1) the Quarterly Report on Form 10-Q of the Company for the quarter ended September 30, 2014 (the “Report”) fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company for the periods presented therein.

Date: October 30, 2014

/s/ Kevin K. Gordon

Kevin K. Gordon

Executive Vice President and Chief Financial Officer

(Principal Financial Officer)

This certification is being furnished solely to accompany the Report pursuant to 18 U.S.C. § 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, and shall not be deemed “filed” by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, and shall not be incorporated by reference into any filing of the Company under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended, whether made before or after the date of this Report, irrespective of any general incorporation language contained in such filing.

A signed original of this written statement required by Section 906 of the Sarbanes-Oxley Act of 2002 has been provided to the Company and will be retained by the Company and furnished to the Securities and Exchange Commission or its staff upon request.

XML

Accounts Receivable and Unbilled Services - Accounts Receivable and Unbilled Services (Detail) (USD $) In Thousands, unless otherwise specified	Sep. 30, 2014	Dec. 31, 2013
Trade:
Billed	$ 474,717	$ 408,959
Unbilled services	559,848	516,942
Trade accounts receivable and unbilled services, gross	1,034,565	925,901
Allowance for doubtful accounts	(2,012)	(1,696)
Trade accounts receivable and unbilled services, net	$ 1,032,553	$ 924,205

XML

Employee Benefit Plans - Summary of Components of Pension Expenses Related to Defined Benefit Plans (Detail) (USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Compensation and Retirement Disclosure [Abstract]
Service cost	$ 3,275	$ 2,916	$ 9,953	$ 9,050
Interest cost	991	912	2,981	2,770
Expected return on plan assets	(935)	(705)	(2,805)	(2,083)
Amortization of prior service costs	20	83	60	255
Amortization of actuarial losses	167	169	512	513
Total pension expense related to defined benefit plans	$ 3,518	$ 3,375	$ 10,701	$ 10,505

XML

Shareholders' Deficit - Additional Information (Detail) (USD $)	0 Months Ended		0 Months Ended
	Oct. 30, 2013 Share Repurchase Program [Member]	Sep. 30, 2014 Share Repurchase Program [Member]	May 28, 2014 Private Share Repurchase [Member]	May 27, 2014 Private Share Repurchase [Member]
Class of Stock [Line Items]
Repurchase of common stock, shares	300		3,287,209
Repurchase of common stock, value	$ 14,000		$ 165,100,000
Repurchase of common stock, share price	$ 47.51		$ 50.23	$ 51.26
Equity available for repurchase under the repurchase program		59,500,000
Equity repurchase program authorized amount	$ 125,000,000
Repurchase price per share percentage				98.00%

XML

Employee Benefit Plans - Additional Information (Detail) (USD $)	9 Months Ended
	Sep. 30, 2014	Dec. 31, 2013
Cost Reduction Initiative Disclosure [Line Items]
Severance expenses payable	$ 7,494,000	$ 14,056,000
Severance expense, net of reversals	2,111,000
Corporate, Non-Segment [Member]
Cost Reduction Initiative Disclosure [Line Items]
Severance expense, net of reversals	47,000,000
Product Development [Member]
Cost Reduction Initiative Disclosure [Line Items]
Severance expense, net of reversals	2,200,000
Integrated Healthcare Services [Member]
Cost Reduction Initiative Disclosure [Line Items]
Severance expense, net of reversals	105,000,000
Cost Reduction Initiative [Member]
Cost Reduction Initiative Disclosure [Line Items]
Severance expenses payable	$ 7,500,000	$ 14,100,000
Number of positions expected to be eliminated	270

XML

Fair Value Measurements - Changes in Level 3 Financial Assets and Liabilities Measured on Recurring Basis (Detail) (Level 3 [Member], USD $) In Thousands, unless otherwise specified	9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013
Accounts Payable and Accrued Expenses and Other Liabilities [Member] | Contingent Consideration [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Beginning Balance, contingent Consideration	$ 13,014	$ 3,521
Initial estimate of contingent consideration		14,300
Revaluations included in earnings	(8,571)	(1,352)
Ending Balance, contingent Consideration	4,443	16,469
Deposits and Other Assets [Member] | Warrants [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Beginning Balance, Warrants	211	29
Initial estimate of contingent consideration
Revaluations included in earnings	(198)	62
Ending Balance, Warrants	$ 13	$ 91

XML

Segments (Tables)

9 Months Ended

Sep. 30, 2014

Segment Reporting [Abstract]

Operations by Reportable Segments

The Company does not allocate restructuring or impairment charges to its segments. Information presented below is in thousands:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
Service revenues
Product Development	$	771,361	$	714,244	$	2,323,376	$	2,144,721
Integrated Healthcare Services		289,652		218,483		778,401		659,679
Total service revenues		1,061,013		932,727		3,101,777		2,804,400
Costs of revenue, service costs
Product Development		458,731		426,094		1,374,492		1,296,996
Integrated Healthcare Services		232,320		174,600		634,795		532,473
Total costs of revenue, service costs		691,051		600,694		2,009,287		1,829,469
Selling, general and administrative
Product Development		154,460		147,534		471,697		438,341
Integrated Healthcare Services		37,447		32,221		103,069		96,792
General corporate and unallocated		27,120		19,818		82,517		92,580
Total selling, general and administrative		219,027		199,573		657,283		627,713
Income from operations
Product Development		158,170		140,616		477,187		409,384
Integrated Healthcare Services		19,885		11,662		40,537		30,414
General corporate and unallocated		(27,120)		(19,818)		(82,517)		(92,580)
Restructuring costs		(1,793)		(7,201)		(3,749)		(11,897)
Total income from operations.	$	149,142	$	125,259	$	431,458	$	335,321

Depreciation and Amortization Expense

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
Depreciation and amortization expense
Product Development	$	23,106	$	20,853	$	69,867	$	57,901
Integrated Healthcare Services		5,803		5,077		15,548		15,697
General corporate and unallocated		1,271		1,394		3,698		3,352
Total depreciation and amortization expense	$	30,180	$	27,324	$	89,113	$	76,950

XML

Income Taxes - Additional Information (Detail) (USD $) In Millions, unless otherwise specified	Sep. 30, 2014
Minimum [Member]
Income Tax Examination [Line Items]
Unrecognized income tax benefits	$ 0
Maximum [Member]
Income Tax Examination [Line Items]
Unrecognized income tax benefits	$ 16.6

XML

Accounts Receivable and Unbilled Services (Tables)

9 Months Ended

Sep. 30, 2014

Receivables [Abstract]

Accounts Receivable and Unbilled Services

Accounts receivable and unbilled services consist of the following (in thousands):

	September 30, 2014			December 31, 2013
Trade:
Billed	$	474,717		$	408,959
Unbilled services		559,848			516,942
		1,034,565			925,901
Allowance for doubtful accounts		(2,012	)		(1,696	)
	$	1,032,553		$	924,205

XML

Business Combinations - Summary of Preliminary Fair Value of Net Assets Acquired at the Date of Acquisition (Detail) (USD $) In Thousands, unless otherwise specified	Sep. 30, 2014
Assets acquired:
Cash and cash equivalents	$ 2,223
Accounts receivable and unbilled services	17,714
Other current assets	443
Property and equipment	289
Goodwill	62,778
Other identifiable intangibles	14,150
Deferred income tax asset - long-term	396
Liabilities assumed:
Accounts payable and accrued expenses	(4,206)
Other	(31)
Net assets acquired	$ 93,756

XML

Derivatives - Summary of Fair Values of Derivative Instruments Designated as Hedges (Detail) (Designated as Hedging Instrument [Member], USD $) In Thousands, unless otherwise specified	Sep. 30, 2014	Dec. 31, 2013
Foreign Exchange Forward Contracts [Member] | Other Current Assets [Member]
Derivatives, Fair Value [Line Items]
Derivative asset fair value		$ 3,950
Foreign Exchange Forward Contracts [Member] | Other Current Liabilities [Member]
Derivatives, Fair Value [Line Items]
Derivative liability fair value	2,410
Interest Rate Swaps [Member] | Other Current Liabilities [Member]
Derivatives, Fair Value [Line Items]
Derivative liability fair value	$ 17,185	$ 24,805

XML

Employee Stock Compensation - Assumptions Used to Estimate Value of Share-Based Compensation for Stock Options and Stock Appreciation Rights Issued (Detail)	3 Months Ended	9 Months Ended
	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Share based Compensation Arrangement by Share based Payment Award, Fair Value Assumptions, Method Used [Line Items]
Expected volatility, Minimum	22.00%	31.00%	18.00%
Expected volatility, Maximum	44.00%	43.00%	47.00%
Weighted average expected volatility	33.00%	37.00%	40.00%
Expected dividends	0.00%	0.00%
Risk-free interest rate, Minimum	0.04%	0.99%	0.04%
Risk-free interest rate, Maximum	2.08%	2.21%	2.08%
Minimum [Member]
Share based Compensation Arrangement by Share based Payment Award, Fair Value Assumptions, Method Used [Line Items]
Expected dividends			0.00%
Expected term (in years)	3 months	3 years 8 months 12 days	3 months
Maximum [Member]
Share based Compensation Arrangement by Share based Payment Award, Fair Value Assumptions, Method Used [Line Items]
Expected dividends			5.45%
Expected term (in years)	6 years 4 months 24 days	6 years 8 months 12 days	6 years 4 months 24 days

XML

Restructuring - Additional Information (Detail) (USD $)	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Restructuring Cost and Reserve [Line Items]
Restructuring costs	$ 1,793,000	$ 7,201,000	$ 3,749,000	$ 11,897,000
2014 Restructuring Plan [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring plan approved	13,000,000		13,000,000
Number of positions expected to reduce			350
2014 Restructuring Plan [Member] | Product Development [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring costs			3,900,000
2014 Restructuring Plan [Member] | Integrated Healthcare Services [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring costs			$ 700,000

XML

Segments - Operations by Reportable Segments (Detail) (USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Segment Reporting Information [Line Items]
Service revenues	$ 1,061,013	$ 932,727	$ 3,101,777	$ 2,804,400
Costs of revenue, service costs	691,051	600,694	2,009,287	1,829,469
Selling, general and administrative	219,027	199,573	657,283	627,713
Income from operations	149,142	125,259	431,458	335,321
Restructuring costs	(1,793)	(7,201)	(3,749)	(11,897)
Operating Segments [Member] | Product Development [Member]
Segment Reporting Information [Line Items]
Service revenues	771,361	714,244	2,323,376	2,144,721
Costs of revenue, service costs	458,731	426,094	1,374,492	1,296,996
Selling, general and administrative	154,460	147,534	471,697	438,341
Income from operations	158,170	140,616	477,187	409,384
Operating Segments [Member] | Integrated Healthcare Services [Member]
Segment Reporting Information [Line Items]
Service revenues	289,652	218,483	778,401	659,679
Costs of revenue, service costs	232,320	174,600	634,795	532,473
Selling, general and administrative	37,447	32,221	103,069	96,792
Income from operations	19,885	11,662	40,537	30,414
Corporate, Non-Segment [Member]
Segment Reporting Information [Line Items]
Selling, general and administrative	27,120	19,818	82,517	92,580
Income from operations	(27,120)	(19,818)	(82,517)	(92,580)
Segment Reconciling Items [Member]
Segment Reporting Information [Line Items]
Restructuring costs	$ (1,793)	$ (7,201)	$ (3,749)	$ (11,897)

XML

Fair Value Measurements - Additional Information (Detail) (USD $)	Sep. 30, 2014	Dec. 31, 2013
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Other identifiable intangibles, net	$ 288,266,000	$ 298,054,000
Long term debt	2,000,000,000	2,100,000,000
Non-recurring Fair Value Measurements [Member] | Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cost and equity method investments	67,400,000
Goodwill	468,600,000
Other identifiable intangibles, net	288,300,000
Fair value of assets	824,300,000
Non-recurring Fair Value Measurements [Member] | Level 3 [Member] | Equity Method Investments [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Unfunded cash commitments	$ 27,400,000

XML

Employee Stock Compensation

9 Months Ended

Sep. 30, 2014

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Employee Stock Compensation

2. Employee Stock Compensation

The Company granted the following share-based awards:

	Three Months Ended September 30,		Nine Months Ended September 30,
	2013		2014		2013
Stock options		100,000		1,359,600		2,200,500
Stock appreciation rights		10,000		176,800		162,600
Restricted stock units		—		36,500		—

No share-based awards were granted during the three months ended September 30, 2014.

The Company had the following share-based awards outstanding:

	September 30, 2014		December 31, 2013
Stock options		9,811,235		10,100,160
Stock appreciation rights		411,363		258,025
Restricted stock units		93,667		57,167

The Company used the following assumptions when estimating the value of the share-based compensation for stock options and stock appreciation rights issued as follows:

	Three Months Ended September 30,	Nine Months Ended September 30,
	2013	2014	2013
Expected volatility	22 –  44%	31 –  43%	18 –  47%
Weighted average expected volatility	33%	37%	40%
Expected dividends	0.0%	0.0%	0.0  –  5.45%
Expected term (in years)	0.25 –  6.4	3.7 – 6.7	0.25  –  6.4
Risk-free interest rate	0.04 – 2.08%	0.99 – 2.21%	0.04 –  2.08%

In November 2013, the Company’s Board of Directors (the “Board”) approved an Employee Stock Purchase Plan (“ESPP”) which was approved by the Company’s shareholders in May 2014. The ESPP allows eligible employees to authorize payroll deductions of up to 10% of their base salary to be applied toward the purchase of full shares of the Company’s common stock on the last day of the offering period. Offering periods under the ESPP are six months in duration and begin on each March 1 and September 1. The first offering period for the ESPP began March 1, 2014. Participating employees will purchase shares on the last day of each offering period at a discount of 15% of the closing price of the common stock on such date as reported on the New York Stock Exchange (“NYSE”). During the three and nine months ended September 30, 2014, the Company issued 46,032 shares of common stock for purchases under the ESPP.

The Company recognized share-based compensation expense of $6.8 million and $5.9 million during the three months ended September 30, 2014 and 2013, respectively, and $22.4 million and $17.0 million during the nine months ended September 30, 2014 and 2013, respectively.

XML

Segments - Depreciation and Amortization Expense (Detail) (USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Segment Reporting Information [Line Items]
Depreciation and amortization expense	$ 30,180	$ 27,324	$ 89,113	$ 76,950
Operating Segments [Member] | Product Development [Member]
Segment Reporting Information [Line Items]
Depreciation and amortization expense	23,106	20,853	69,867	57,901
Operating Segments [Member] | Integrated Healthcare Services [Member]
Segment Reporting Information [Line Items]
Depreciation and amortization expense	5,803	5,077	15,548	15,697
Corporate, Non-Segment [Member]
Segment Reporting Information [Line Items]
Depreciation and amortization expense	$ 1,271	$ 1,394	$ 3,698	$ 3,352

XML

Derivatives - Summary of Details Relating to Fair Value / Losses (Gains) of Derivative Instruments not Designated as Hedges (Detail) (Warrants [Member], Derivatives Not Designated as Hedging Instruments [Member], Deposits and other assets [Member], USD $) In Thousands, unless otherwise specified	Sep. 30, 2014	Dec. 31, 2013
Warrants [Member] | Derivatives Not Designated as Hedging Instruments [Member] | Deposits and other assets [Member]
Derivatives, Fair Value [Line Items]
Derivative asset fair value	$ 13	$ 211

XML

Business Combinations (Tables)

9 Months Ended

Sep. 30, 2014

Business Combinations [Abstract]

Summary of Preliminary Fair Value of Net Assets Acquired at Date of Acquisition

The following table summarizes the preliminary fair value of the net assets acquired of Encore at the date of the acquisition (in thousands):

Assets acquired:

Cash and cash equivalents	$	2,223
Accounts receivable and unbilled services		17,714
Other current assets		443
Property and equipment		289
Goodwill		62,778
Other identifiable intangibles		14,150
Deferred income tax asset – long-term		396
Liabilities assumed:
Accounts payable and accrued expenses		(4,206	)
Other		(31	)
Net assets acquired	$	93,756

Summary Of Identifiable Definite Lived Intangible Assets

The identifiable definite-lived intangible assets consisted of the following:

Other identifiable intangibles (in thousands)
Customer relationships	$	8,800
Acquired backlog		800
Trade names		1,100
Non-compete agreements		450
Software		3,000
Total other identifiable intangibles	$	14,150
Amortized over a weighted average useful life (in years)		8

XML

Fair Value Measurements (Tables)

9 Months Ended

Sep. 30, 2014

Fair Value Disclosures [Abstract]

Fair Value of Financial Assets and Liabilities Measured on Recurring Basis

The following table summarizes the fair value of the Company’s financial assets and liabilities that are measured on a recurring basis as of September 30, 2014 (in thousands):

	Level 1		Level 2		Level 3		Total
Assets:
Marketable equity securities	$	1,045	$	—	$	—	$	1,045
Warrants		—		—		13		13
Total	$	1,045	$	—	$	13	$	1,058
Liabilities:
Foreign exchange forward contracts	$	—	$	2,410	$	—	$	2,410
Interest rate swaps		—		17,185		—		17,185
Contingent consideration		—		—		4,443		4,443
Total	$	—	$	19,595	$	4,443	$	24,038

Changes in Level 3 Financial Assets and Liabilities Measured on Recurring Basis

The following table summarizes the changes in Level 3 financial assets and liabilities measured on a recurring basis for the nine months ended September 30 (in thousands):

	Warrants–Deposits and Other Assets				Contingent Consideration – Accounts Payable and Accrued Expenses and Other Liabilities
	2014		2013		2014		2013
Balance as of January 1	$	211	$	29	$	13,014	$	3,521
Initial estimate of contingent consideration		—		—		—		14,300
Revaluations included in earnings		(198)		62		(8,571)		(1,352)
Balance as of September 30	$	13	$	91	$	4,443	$	16,469

XML

Employee Benefit Plans - Summary of Severance Associated with Cost Reduction Programs (Detail) (USD $) In Thousands, unless otherwise specified	9 Months Ended
	Sep. 30, 2014
Compensation and Retirement Disclosure [Abstract]
Severance expenses payable, opening balance	$ 14,056
Severance expense, net of reversals	(2,111)
Severance payments	(4,418)
Severance foreign currency translation	(33)
Severance expenses payable, ending balance	$ 7,494

XML

Derivatives - Effect of Cash Flow Hedging Instruments on Other Comprehensive Income (Loss) (Detail) (Derivatives Designated As Cash Flow Hedges [Member], USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Derivative Instruments and Hedging Activities Disclosures [Line Items]
Effect of cash flow hedging instruments on other comprehensive income (loss)	$ (1,908)	$ 5,654	$ 1,260	$ 9,486
Foreign Exchange Forward Contracts [Member]
Derivative Instruments and Hedging Activities Disclosures [Line Items]
Effect of cash flow hedging instruments on other comprehensive income (loss)	(5,216)	4,273	(6,360)	2,648
Interest Rate Swaps [Member]
Derivative Instruments and Hedging Activities Disclosures [Line Items]
Effect of cash flow hedging instruments on other comprehensive income (loss)	$ 3,308	$ 1,381	$ 7,620	$ 6,838

XML

Restructuring (Tables)

9 Months Ended

Sep. 30, 2014

Restructuring and Related Activities [Abstract]

Summary of Amounts Recorded for Restructuring Plans

The following amounts were recorded for the February 2014 restructuring plan and the restructuring plans initiated in prior years (in thousands):

	Severance and Related Costs			Exit Costs			Total
Balance at December 31, 2013	$	5,276		$	198		$	5,474
Expense, net of reversals		3,749			—			3,749
Payments		(5,476	)		(119	)		(5,595	)
Foreign currency translation		(142	)		—			(142	)
Balance at September 30, 2014	$	3,407		$	79		$	3,486

XML

Employee Benefit Plans (Tables)

9 Months Ended

Sep. 30, 2014

Postemployment Benefits [Abstract]

Summary of Components of Pension Expenses Related to Defined Benefit Plans

The following table summarizes the components of pension expense related to the Company’s defined benefit plans (in thousands):

	Three Months Ended September 30,						Nine Months Ended September 30,
	2014			2013			2014			2013
Service cost	$	3,275		$	2,916		$	9,953		$	9,050
Interest cost		991			912			2,981			2,770
Expected return on plan assets		(935	)		(705	)		(2,805	)		(2,083	)
Amortization of prior service costs		20			83			60			255
Amortization of actuarial losses		167			169			512			513
	$	3,518		$	3,375		$	10,701		$	10,505

Summary of Severance Associated with Cost Reduction Programs

The following amounts were recorded for the severance associated with cost reduction programs (in thousands):

Balance at December 31, 2013	$	14,056
Expense, net of reversals		(2,111	)
Payments		(4,418	)
Foreign currency translation		(33	)
Balance at September 30, 2014	$	7,494

XML

Basis of Presentation

9 Months Ended

Sep. 30, 2014

Accounting Policies [Abstract]

Basis of Presentation

1. Basis of Presentation

Unaudited Interim Financial Information

The accompanying unaudited condensed consolidated financial statements of Quintiles Transnational Holdings Inc. and its subsidiaries (the “Company”) have been prepared in accordance with generally accepted accounting principles in the United States of America (“GAAP”) for interim financial information. Accordingly, they do not include all of the information and notes required by GAAP for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring adjustments) considered necessary for a fair statement of the Company’s financial condition and results of operations have been included. Operating results for the periods presented are not necessarily indicative of the results that may be expected for the year ending December 31, 2014. As such, the information included in this quarterly report on Form 10-Q should be read in conjunction with the Company’s audited consolidated financial statements included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2013. The balance sheet at December 31, 2013 has been derived from the audited consolidated financial statements of the Company but does not include all the disclosures required by GAAP.

Reclassifications

Certain immaterial prior period amounts have been reclassified to conform to current period presentation. These changes had no effect on previously reported total revenues, net income, comprehensive income or shareholders’ deficit.

Recently Issued Accounting Standards

In May 2014, the United States Financial Accounting Standards Board and the International Accounting Standards Board issued a converged standard on the recognition of revenue from contracts with customers. The objective of the new standard is to establish a single comprehensive revenue recognition model that is designed to create greater comparability of financial statements across industries and jurisdictions. Under the new standard, companies will recognize revenue to depict the transfer of goods or services to customers in amounts that reflect the consideration to which the company expects to be entitled in exchange for those goods or services. The new standard also will require expanded disclosures on revenue recognition and changes in assets and liabilities that result from contracts with customers. The Company will adopt the new standard on January 1, 2017, as required. Early adoption is not permitted. The Company is currently evaluating the impact of this new standard on its consolidated financial statements.

XML

Comprehensive Income (Tables)

9 Months Ended

Sep. 30, 2014

Equity [Abstract]

Summary of Components of AOCI

Below is a summary of the components of AOCI (in thousands):

	Foreign Currency Translation		Marketable Securities		Derivative Instruments		Defined Benefit Plans		Income Taxes		AOCI
Balance at December 31, 2013	$	(5,829)	$	5,708	$	(20,855)	$	(5,044)	$	25,644	$	(376)
Other comprehensive (loss) income before reclassifications		(24,523)		(763)		(3,301)		—		2,692		(25,895)
Reclassification adjustments		—		(5,004)		4,561		572		(903)		(774)
Balance at September 30, 2014	$	(30,352)	$	(59)	$	(19,595)	$	(4,472)	$	27,433	$	(27,045)

Summary of (Gains) Losses Reclassified from AOCI into Condensed Consolidated Statements of Income and Affected Financial Statement Line Item

Below is a summary of the (gains) losses reclassified from AOCI into the condensed consolidated statements of income and the affected financial statement line item (in thousands):

Reclassification Adjustments	Affected Financial Statement Line Item	Three Months Ended September 30,				Nine Months Ended September 30,
		2014		2013		2014		2013
Marketable securities:
Marketable securities	Other (income) expense, net	$	—	$	—	$	(5,004)	$	—
Total before income taxes			—		—		(5,004)		—
Income tax expense			—		—		(1,927)		—
Total net of income taxes		$	—	$	—	$	(3,077)	$	—
Derivative instruments:
Interest rate swaps	Interest expense	$	3,149	$	3,248	$	9,344	$	9,433
Foreign exchange forward contracts	Service revenues		(614)		121		(4,783)		1,442
Total before income taxes			2,535		3,369		4,561		10,875
Income tax benefit			1,086		1,285		2,616		3,973
Total net of income taxes		$	1,449	$	2,084	$	1,945	$	6,902
Defined benefit plans:
Amortization of prior service costs	See Note 11	$	20	$	83	$	60	$	255
Amortization of actuarial losses	See Note 11		167		169		512		513
Total before income taxes			187		252		572		768
Income tax benefit			70		95		214		290
Total net of income taxes		$	117	$	157	$	358	$	478

XML

Goodwill - Summary of Goodwill by Segment (Detail) (USD $) In Thousands, unless otherwise specified	9 Months Ended
	Sep. 30, 2014
Goodwill [Line Items]
Beginning balance	$ 409,626
Acquisition	62,778
Impact of foreign currency fluctuations and other	(3,784)
Ending balance	468,620
Product Development [Member]
Goodwill [Line Items]
Beginning balance	351,144
Acquisition
Impact of foreign currency fluctuations and other	(2,623)
Ending balance	348,521
Integrated Healthcare Services [Member]
Goodwill [Line Items]
Beginning balance	58,482
Acquisition	62,778
Impact of foreign currency fluctuations and other	(1,161)
Ending balance	$ 120,099

XML

Restructuring - Summary of Amounts Recorded for Restructuring Plans (Detail) (USD $) In Thousands, unless otherwise specified	9 Months Ended
	Sep. 30, 2014
Restructuring Cost and Reserve [Line Items]
Restructuring reserves, beginning balance	$ 5,474
Expense, net of reversals	3,749
Payments	(5,595)
Foreign currency translation	(142)
Restructuring reserves, ending balance	3,486
Severance and Related Costs [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring reserves, beginning balance	5,276
Expense, net of reversals	3,749
Payments	(5,476)
Foreign currency translation	(142)
Restructuring reserves, ending balance	3,407
Exit Costs [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring reserves, beginning balance	198
Payments	(119)
Restructuring reserves, ending balance	$ 79

XML

CONDENSED CONSOLIDATED STATEMENTS OF INCOME (unaudited) (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Income Statement [Abstract]
Service revenues	$ 1,061,013	$ 932,727	$ 3,101,777	$ 2,804,400
Reimbursed expenses	339,021	263,112	947,133	915,960
Total revenues	1,400,034	1,195,839	4,048,910	3,720,360
Costs of revenue, service costs	691,051	600,694	2,009,287	1,829,469
Costs of revenue, reimbursed expenses	339,021	263,112	947,133	915,960
Selling, general and administrative	219,027	199,573	657,283	627,713
Restructuring costs	1,793	7,201	3,749	11,897
Income from operations	149,142	125,259	431,458	335,321
Interest income	(602)	(1,119)	(2,851)	(2,356)
Interest expense	25,050	28,756	74,552	96,682
Loss on extinguishment of debt				16,543
Other (income) expense, net	(7,776)	3,224	(9,564)	1,378
Income before income taxes and equity in earnings (losses) of unconsolidated affiliates	132,470	94,398	369,321	223,074
Income tax expense	41,260	27,459	111,049	68,407
Income before equity in earnings (losses) of unconsolidated affiliates	91,210	66,939	258,272	154,667
Equity in earnings (losses) of unconsolidated affiliates	1,523	(355)	9,785	(1,574)
Net income	92,733	66,584	268,057	153,093
Net (income) loss attributable to noncontrolling interests	(79)	185	(100)	502
Net income attributable to Quintiles Transnational Holdings Inc.	$ 92,654	$ 66,769	$ 267,957	$ 153,595
Earnings per share attributable to common shareholders:
Basic	$ 0.73	$ 0.52	$ 2.08	$ 1.25
Diluted	$ 0.71	$ 0.50	$ 2.03	$ 1.22
Weighted average common shares outstanding:
Basic	127,462	128,923	128,780	122,467
Diluted	130,626	133,267	131,903	126,195

XML

Fair Value Measurements - Fair Value of Financial Assets and Liabilities Measured on Recurring Basis (Detail) (Recurring Fair Value Measurements [Member], USD $) In Thousands, unless otherwise specified	Sep. 30, 2014
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets	$ 1,058
Fair value of liabilities	24,038
Warrants [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets	13
Foreign Exchange Forward Contracts [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities	2,410
Interest Rate Swaps [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities	17,185
Contingent Consideration [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities	4,443
Marketable Equity Securities [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets	1,045
Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets	1,045
Fair value of liabilities
Level 1 [Member] | Warrants [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets
Level 1 [Member] | Foreign Exchange Forward Contracts [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities
Level 1 [Member] | Interest Rate Swaps [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities
Level 1 [Member] | Contingent Consideration [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities
Level 1 [Member] | Marketable Equity Securities [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets	1,045
Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets
Fair value of liabilities	19,595
Level 2 [Member] | Warrants [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets
Level 2 [Member] | Foreign Exchange Forward Contracts [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities	2,410
Level 2 [Member] | Interest Rate Swaps [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities	17,185
Level 2 [Member] | Contingent Consideration [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities
Level 2 [Member] | Marketable Equity Securities [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets
Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets	13
Fair value of liabilities	4,443
Level 3 [Member] | Warrants [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets	13
Level 3 [Member] | Foreign Exchange Forward Contracts [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities
Level 3 [Member] | Interest Rate Swaps [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities
Level 3 [Member] | Contingent Consideration [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of liabilities	4,443
Level 3 [Member] | Marketable Equity Securities [Member]
Fair Value, Assets and Liabilities Measured on Recurring Basis [Line Items]
Fair value of assets

XML

CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) (USD $)	Sep. 30, 2014	Dec. 31, 2013
Statement of Financial Position [Abstract]
Common stock, shares authorized	300,000,000	300,000,000
Common stock, par value	$ 0.01	$ 0.01
Common stock, shares issued	127,696,000	129,652,000
Common stock, shares outstanding	127,696,000	129,652,000

XML

Comprehensive Income - Summary of (Gains) Losses Reclassified from AOCI into Condensed Consolidated Statements of Income and Affected Financial Statement Line Item (Detail) (USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items]
Amortization of prior service costs	$ 20	$ 83	$ 60	$ 255
Marketable securities, Other (income) expense, net	(7,776)	3,224	(9,564)	1,378
Amortization of actuarial losses	167	169	512	513
Income tax expense/benefit	(41,260)	(27,459)	(111,049)	(68,407)
Foreign exchange forward contracts, Service revenues	(1,400,034)	(1,195,839)	(4,048,910)	(3,720,360)
Marketable Securities [Member] | Reclassification Adjustments from Accumulated Other Comprehensive (Loss) Income [Member]
Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items]
Marketable securities, Other (income) expense, net			(5,004)
Total before income taxes			(5,004)
Income tax expense/benefit			(1,927)
Total net of income taxes			(3,077)
Defined Benefit Plans [Member] | Reclassification Adjustments from Accumulated Other Comprehensive (Loss) Income [Member]
Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items]
Amortization of prior service costs	20	83	60	255
Amortization of actuarial losses	167	169	512	513
Total before income taxes	187	252	572	768
Income tax expense/benefit	70	95	214	290
Total net of income taxes	117	157	358	478
Derivative [Member] | Derivative Instruments [Member] | Reclassification Adjustments from Accumulated Other Comprehensive (Loss) Income [Member]
Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items]
Total before income taxes	2,535	3,369	4,561	10,875
Income tax expense/benefit	1,086	1,285	2,616	3,973
Total net of income taxes	1,449	2,084	1,945	6,902
Interest Rate Swaps [Member] | Derivative Instruments [Member] | Reclassification Adjustments from Accumulated Other Comprehensive (Loss) Income [Member]
Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items]
Interest rate swaps, Interest expense	3,149	3,248	9,344	9,433
Foreign Exchange Forward Contracts [Member] | Derivative Instruments [Member] | Reclassification Adjustments from Accumulated Other Comprehensive (Loss) Income [Member]
Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items]
Foreign exchange forward contracts, Service revenues	$ (614)	$ 121	$ (4,783)	$ 1,442

XML

Employee Stock Compensation - Schedule of Share-Based Awards Granted and Outstanding (Detail)	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013	Dec. 31, 2013
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]
Stock options granted	0	100,000	1,359,600	2,200,500
Stock appreciation rights granted		10,000	176,800	162,600
Restricted stock units granted			36,500
Stock options outstanding	9,811,235		9,811,235		10,100,160
Stock appreciation rights outstanding	411,363		411,363		258,025
Restricted stock units outstanding	93,667		93,667		57,167

XML

Earnings Per Share

9 Months Ended

Sep. 30, 2014

Earnings Per Share [Abstract]

Earnings Per Share

15. Earnings Per Share

The following table shows the weighted average number of outstanding share-based awards not included in the computation of diluted earnings per share as the effect of including such share-based awards in the computation would be anti-dilutive (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
Weighted average shares subject to anti-dilutive share-based awards		1,324		2,057		1,229		1,635

Share-based awards will have a dilutive effect under the treasury method only when the respective period’s average market value of the Company’s common stock exceeds the exercise proceeds.

XML

Employee Stock Compensation - Additional Information (Detail) (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock options granted	0	100,000	1,359,600	2,200,500
Share based compensation expense	$ 6,800	$ 5,900	$ 22,388	$ 16,960
Employee Stock Purchase Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Employee stock purchase plan payroll deductions percent	10.00%		10.00%
Discount on closing price of share			15.00%
Common stock shares purchase	46,032		46,032

XML

Employee Stock Compensation (Tables)

9 Months Ended

Sep. 30, 2014

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Share-Based Awards Granted and Outstanding

The Company granted the following share-based awards:

	Three Months Ended September 30,		Nine Months Ended September 30,
	2013		2014		2013
Stock options		100,000		1,359,600		2,200,500
Stock appreciation rights		10,000		176,800		162,600
Restricted stock units		—		36,500		—

No share-based awards were granted during the three months ended September 30, 2014.

The Company had the following share-based awards outstanding:

	September 30, 2014		December 31, 2013
Stock options		9,811,235		10,100,160
Stock appreciation rights		411,363		258,025
Restricted stock units		93,667		57,167

Assumptions Used to Estimate Value of Share-Based Compensation for Stock Options and Stock Appreciation Rights Issued

The Company used the following assumptions when estimating the value of the share-based compensation for stock options and stock appreciation rights issued as follows:

	Three Months Ended September 30,	Nine Months Ended September 30,
	2013	2014	2013
Expected volatility	22 –  44%	31 –  43%	18 –  47%
Weighted average expected volatility	33%	37%	40%
Expected dividends	0.0%	0.0%	0.0  –  5.45%
Expected term (in years)	0.25 –  6.4	3.7 – 6.7	0.25  –  6.4
Risk-free interest rate	0.04 – 2.08%	0.99 – 2.21%	0.04 –  2.08%

XML

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited) (USD $) In Thousands, unless otherwise specified	9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013
Operating activities:
Net income	$ 268,057	$ 153,093
Adjustments to reconcile net income to cash provided by operating activities:
Depreciation and amortization	89,113	76,950
Amortization of debt issuance costs and discount	4,787	16,944
Share-based compensation	22,388	16,960
(Earnings) loss from unconsolidated affiliates	(9,763)	1,454
Gain on investments, net	(4,806)	(62)
Benefit from deferred income taxes	(11,529)	(15,883)
Excess income tax benefits from share-based award activities	(12,802)	(145)
Changes in operating assets and liabilities:
Change in accounts receivable, unbilled services and unearned income	(118,721)	(74,533)
Change in other operating assets and liabilities	(50,927)	3,133
Net cash provided by operating activities	175,797	177,911
Investing activities:
Acquisition of property, equipment and software	(57,782)	(73,940)
Acquisition of businesses, net of cash acquired	(92,201)	(144,970)
Proceeds from sale of equity securities	5,861	60
Investments in and advances to unconsolidated affiliates, net of payments received	(2,137)	(5,944)
Other	332	802
Net cash used in investing activities	(145,927)	(223,992)
Financing activities:
Repayment of debt and principal payments on capital lease obligations	(6,729)	(385,807)
Issuance of common stock, net of costs	(105)	489,560
Stock issued under employee stock purchase and option plans	23,201	364
Repurchase of common stock	(165,131)
Payroll taxes remitted on repurchase of stock options	(8,415)
Excess income tax benefits from share-based award activities	12,802	145
Net cash (used in) provided by financing activities	(144,377)	104,262
Effect of foreign currency exchange rate changes on cash	(18,602)	(16,199)
(Decrease) increase in cash and cash equivalents	(133,109)	41,982
Cash and cash equivalents at beginning of period	778,143	567,728
Cash and cash equivalents at end of period	$ 645,034	$ 609,710

XML

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (unaudited) (USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Statement of Comprehensive Income [Abstract]
Net income	$ 92,733	$ 66,584	$ 268,057	$ 153,093
Unrealized (losses) gains on marketable securities, net of income taxes of ($4), $821, ($294) and $847	(6)	1,315	(469)	1,357
Unrealized (losses) gains on derivative instruments, net of income taxes of ($882), $159, ($990) and ($815)	(3,561)	2,126	(2,311)	(574)
Foreign currency translation, net of income taxes of ($1,408), ($2,048), ($1,408) and ($2,378)	(27,280)	8,622	(23,116)	(19,732)
Reclassification adjustments:
Gains on marketable securities included in net income, net of income taxes of ($1,927)			(3,077)
Losses on derivative instruments included in net income, net of income taxes of $1,086, $1,285, $2,616 and $3,973	1,449	2,084	1,945	6,902
Amortization of prior service costs and losses included in net income, net of income taxes of $70, $95, $214 and $290	117	157	358	478
Comprehensive income	63,452	80,888	241,387	141,524
Comprehensive (income) loss attributable to noncontrolling interests	(87)	175	(99)	484
Comprehensive income attributable to Quintiles Transnational Holdings Inc.	$ 63,365	$ 81,063	$ 241,288	$ 142,008

XML

Restructuring

9 Months Ended

Sep. 30, 2014

Restructuring and Related Activities [Abstract]

Restructuring

10. Restructuring

In 2014, the Board approved restructuring plans of approximately $13 million to better align resources with the Company’s strategic direction. These actions are expected to occur throughout 2014 and are expected to result in severance for approximately 350 positions. Through September 30, 2014, the Company has recognized approximately $3.9 million and $700,000 of restructuring costs related to these plans for activities in the Product Development and Integrated Healthcare Services segments, respectively. All of the restructuring costs are related to severance costs. Restructuring costs are not allocated to the Company’s reportable segments as they are not part of the segment performance measures regularly reviewed by management.

The following amounts were recorded for the February 2014 restructuring plan and the restructuring plans initiated in prior years (in thousands):

	Severance and Related Costs			Exit Costs			Total
Balance at December 31, 2013	$	5,276		$	198		$	5,474
Expense, net of reversals		3,749			—			3,749
Payments		(5,476	)		(119	)		(5,595	)
Foreign currency translation		(142	)		—			(142	)
Balance at September 30, 2014	$	3,407		$	79		$	3,486

The Company expects the majority of the restructuring accruals at September 30, 2014 will be paid in 2014.

XML

Document and Entity Information	9 Months Ended
	Sep. 30, 2014	Oct. 23, 2014
Document And Entity Information [Abstract]
Document Type	10-Q
Amendment Flag	false
Document Period End Date	Sep. 30, 2014
Document Fiscal Year Focus	2014
Document Fiscal Period Focus	Q3
Trading Symbol	Q
Entity Registrant Name	Quintiles Transnational Holdings Inc.
Entity Central Index Key	0001478242
Current Fiscal Year End Date	--12-31
Entity Filer Category	Non-accelerated Filer
Entity Common Stock, Shares Outstanding		127,799,825

XML

Employee Benefit Plans

9 Months Ended

Sep. 30, 2014

Postemployment Benefits [Abstract]

Employee Benefit Plans

11. Employee Benefit Plans

Defined Benefit Plans

The following table summarizes the components of pension expense related to the Company’s defined benefit plans (in thousands):

	Three Months Ended September 30,						Nine Months Ended September 30,
	2014			2013			2014			2013
Service cost	$	3,275		$	2,916		$	9,953		$	9,050
Interest cost		991			912			2,981			2,770
Expected return on plan assets		(935	)		(705	)		(2,805	)		(2,083	)
Amortization of prior service costs		20			83			60			255
Amortization of actuarial losses		167			169			512			513
	$	3,518		$	3,375		$	10,701		$	10,505

Other

As of September 30, 2014 and December 31, 2013, the Company has a severance accrual included in accounts payable and accrued expenses on the accompanying condensed consolidated balance sheets of $7.5 million and $14.1 million, respectively. The Company recognizes obligations associated with severance related to contractual termination benefits at fair value on the date that it is probable that the affected employees will be entitled to the benefit and the amount can reasonably be estimated. The severance accrual is related to cost reduction programs that will result in severance for approximately 270 positions, which are expected to lower operating costs and improve profitability by reducing excess capacity. These actions are expected to occur and be paid during 2014 and 2015. During the first nine months of 2014, the Company has recognized approximately $2.1 million of net reversals related to these cost reduction programs, primarily as a result of affected individuals transferring into other positions within the Company. Of the $2.1 million decrease from net reversals recognized for these cost reduction programs, approximately ($2.2) million, $105,000 and ($47,000) were related to activities in the Product Development segment, Integrated Healthcare Services segment and corporate activities, respectively.

The following amounts were recorded for the severance associated with cost reduction programs (in thousands):

Balance at December 31, 2013	$	14,056
Expense, net of reversals		(2,111	)
Payments		(4,418	)
Foreign currency translation		(33	)
Balance at September 30, 2014	$	7,494

XML

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (unaudited) (Parenthetical) (USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Statement of Comprehensive Income [Abstract]
Unrealized (losses) gains on marketable securities, income taxes	$ (4)	$ 821	$ (294)	$ 847
Unrealized (losses) gains on derivative instruments, income taxes	(882)	159	(990)	(815)
Foreign currency translation, income taxes	(1,408)	(2,048)	(1,408)	(2,378)
Gains on marketable securities included in net income, income taxes			1,927
Losses on derivative instruments included in net income, income taxes	1,086	1,285	2,616	3,973
Amortization of prior service costs and losses included in net income, income taxes	$ 70	$ 95	$ 214	$ 290

XML

Goodwill

9 Months Ended

Sep. 30, 2014

Goodwill and Intangible Assets Disclosure [Abstract]

Goodwill

5. Goodwill

The following is a summary of goodwill by segment for the nine months ended September 30, 2014 (in thousands):

	Product Development		Integrated Healthcare Services		Consolidated
Balance as of December 31, 2013	$	351,144	$	58,482	$	409,626
Acquisition		—		62,778		62,778
Impact of foreign currency fluctuations and other		(2,623)		(1,161)		(3,784)
Balance as of September 30, 2014	$	348,521	$	120,099	$	468,620

XML

Accounts Receivable and Unbilled Services

9 Months Ended

Sep. 30, 2014

Receivables [Abstract]

Accounts Receivable and Unbilled Services

4. Accounts Receivable and Unbilled Services

Accounts receivable and unbilled services consist of the following (in thousands):

	September 30, 2014			December 31, 2013
Trade:
Billed	$	474,717		$	408,959
Unbilled services		559,848			516,942
		1,034,565			925,901
Allowance for doubtful accounts		(2,012	)		(1,696	)
	$	1,032,553		$	924,205

XML

Basis of Presentation (Policies)

9 Months Ended

Sep. 30, 2014

Accounting Policies [Abstract]

Unaudited Interim Financial Information

Unaudited Interim Financial Information

The accompanying unaudited condensed consolidated financial statements of Quintiles Transnational Holdings Inc. and its subsidiaries (the “Company”) have been prepared in accordance with generally accepted accounting principles in the United States of America (“GAAP”) for interim financial information. Accordingly, they do not include all of the information and notes required by GAAP for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring adjustments) considered necessary for a fair statement of the Company’s financial condition and results of operations have been included. Operating results for the periods presented are not necessarily indicative of the results that may be expected for the year ending December 31, 2014. As such, the information included in this quarterly report on Form 10-Q should be read in conjunction with the Company’s audited consolidated financial statements included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2013. The balance sheet at December 31, 2013 has been derived from the audited consolidated financial statements of the Company but does not include all the disclosures required by GAAP.

Reclassifications

Reclassifications

Certain immaterial prior period amounts have been reclassified to conform to current period presentation. These changes had no effect on previously reported total revenues, net income, comprehensive income or shareholders’ deficit.

Recently Issued Accounting Standards

Recently Issued Accounting Standards

In May 2014, the United States Financial Accounting Standards Board and the International Accounting Standards Board issued a converged standard on the recognition of revenue from contracts with customers. The objective of the new standard is to establish a single comprehensive revenue recognition model that is designed to create greater comparability of financial statements across industries and jurisdictions. Under the new standard, companies will recognize revenue to depict the transfer of goods or services to customers in amounts that reflect the consideration to which the company expects to be entitled in exchange for those goods or services. The new standard also will require expanded disclosures on revenue recognition and changes in assets and liabilities that result from contracts with customers. The Company will adopt the new standard on January 1, 2017, as required. Early adoption is not permitted. The Company is currently evaluating the impact of this new standard on its consolidated financial statements.

XML

Income Taxes

9 Months Ended

Sep. 30, 2014

Income Tax Disclosure [Abstract]

Income Taxes

12. Income Taxes

Due to the potential for expiration of various federal, state, and foreign statutes of limitation, the Company’s unrecognized income tax benefits may change within the next 12 months by a range of zero to $16.6 million.

XML

Shareholders' Deficit

9 Months Ended

Sep. 30, 2014

Equity [Abstract]

Shareholders' Deficit

8. Shareholders’ Deficit

Equity Repurchase Program

On October 30, 2013, the Board approved an equity repurchase program (the “Repurchase Program”) authorizing the repurchase of up to $125.0 million of either the Company’s common stock or vested in-the-money employee stock options, or a combination thereof. The Company repurchased 300 shares of its common stock for $47.51 per share for an aggregate purchase price of approximately $14,000 during the nine months ended September 30, 2014 under the Repurchase Program. As of September 30, 2014, the Company has remaining authorization under the Repurchase Program to repurchase up to $59.5 million of its common stock. The Repurchase Program for vested in-the-money employee stock options expired in November 2013. The Repurchase Program for common stock does not have an end date.

Private Share Repurchase

On May 28, 2014, the Company completed the repurchase of 3,287,209 shares of its common stock for $50.23 per share from TPG Quintiles Holdco, L.P., one of its existing shareholders, in a private transaction for an aggregate purchase price of approximately $165.1 million. The repurchase price per share of common stock was equal to 98% of the closing market price of the Company’s common stock on the NYSE on May 27, 2014 (which was $51.26). The repurchase of shares from its existing shareholder was authorized in compliance with the Company’s related party transactions approval policy. The Company funded this private repurchase transaction with cash on hand. This private repurchase transaction was separate from and in addition to the Repurchase Program.

XML

Segments - Additional Information (Detail) (USD $) In Millions, unless otherwise specified	3 Months Ended	9 Months Ended
	Jun. 30, 2013	Sep. 30, 2014 Segment
Segment Reporting [Abstract]
Number of reportable segments		2
Management agreement termination fee	$ 25.0
Agreement modification fee	$ 1.5

XML

Derivatives

9 Months Ended

Sep. 30, 2014

Derivative Instruments and Hedging Activities Disclosure [Abstract]

Derivatives

6. Derivatives

As of September 30, 2014, the Company held the following derivative positions: (i) freestanding warrants to purchase shares of common stock of third parties, (ii) forward exchange contracts to protect against foreign exchange movements for certain forecasted foreign currency cash flows related to service contracts and (iii) interest rate swaps to hedge the exposure to variability in interest payments on variable interest rate debt. The Company does not use derivative financial instruments for speculative or trading purposes.

As of September 30, 2014, the Company had freestanding warrants to purchase shares of third parties’ common stock. No quoted price is available for the warrants. Accordingly, the Company uses various valuation techniques to value the warrants, including the present value of estimated expected future cash flows, option-pricing models and fundamental analysis. Factors affecting the valuation include the current price of the underlying common stock, the exercise price of the warrants, the expected time to exercise the warrants, the estimated price volatility of the underlying common stock over the life of the warrants and the restrictions on the transferability of or ability to exercise the warrants. The Company did not sell any warrants during the three and nine months ended September 30, 2014 or 2013.

As of September 30, 2014, the Company had 12 open foreign exchange forward contracts to hedge certain forecasted foreign currency cash flow transactions occurring in 2014 and the first six months of 2015 with notional amounts totaling $75.6 million. As these contracts were executed to hedge the risk of the potential volatility in the cash flows resulting from fluctuations in currency exchange rates during the remainder of 2014 and the first six months of 2015, these transactions are accounted for as cash flow hedges. As such, the effective portion of the gain or loss on the contracts is recorded as unrealized gains (losses) on derivatives included in the accumulated other comprehensive income (loss) (“AOCI”) component of shareholders’ deficit. These hedges are highly effective. Upon expiration of the hedge instruments in 2014 and the first six months of 2015, the Company will reclassify the unrealized holding gains and losses on the derivative instruments included in AOCI into earnings.

On June 9, 2011, the Company entered into six interest rate swaps effective September 28, 2012 and expiring between September 30, 2013 and March 31, 2016 in an effort to limit its exposure to changes in the variable interest rate on its senior secured credit facilities. The critical terms of the interest rate swaps were substantially the same as those of the Company’s senior secured credit facilities, including quarterly interest settlements. These interest rate swaps are being accounted for as cash flow hedges as these transactions were executed to hedge the Company’s interest payments, and these hedges are highly effective. As such, changes in the fair value of these derivative instruments are recorded as unrealized gains (losses) on derivatives included in the AOCI component of shareholders’ deficit. The fair value of these interest rate swaps represents the present value of the anticipated net payments the Company will make to the counterparty, which, when they occur, are reflected as interest expense on the condensed consolidated statements of income. These payments, together with the variable rate of interest incurred on the underlying debt, result in a fixed rate of interest of 2.57% plus the applicable margin on the affected borrowings ($910.0 million or 44.3% of the Company’s variable rate debt at September 30, 2014). The Company expects that $12.2 million of unrealized losses will be reclassified out of AOCI and will form the interest rate swap component of the 2.57% fixed rate of interest to be incurred over the next 12 months as the underlying net payments are settled.

The fair values of the Company’s derivative instruments designated as hedging instruments and the line items on the accompanying condensed consolidated balance sheets to which they were recorded are summarized in the following table (in thousands):

	Balance Sheet Classification	September 30, 2014		December 31, 2013
Foreign exchange forward contracts	Other current assets	$	—	$	3,950
Foreign exchange forward contracts	Other current liabilities	$	2,410	$	—
Interest rate swaps	Other current liabilities	$	17,185	$	24,805

The fair values of the Company’s derivative instruments not designated as hedging instruments and the line items on the accompanying condensed consolidated balance sheets to which they were recorded are summarized in the following table (in thousands):

	Balance Sheet Classification	September 30, 2014	December 31, 2013
Warrants	Deposits and other assets	$              13	$              211

The effect of the Company’s cash flow hedging instruments on other comprehensive income (loss) is summarized in the following table (in thousands):

	Three Months Ended September 30,					Nine Months Ended September 30,
	2014			2013		2014			2013
Foreign exchange forward contracts	$	(5,216	)	$	4,273	$	(6,360	)	$	2,648
Interest rate swaps		3,308			1,381		7,620			6,838
Total	$	(1,908	)	$	5,654	$	1,260		$	9,486

XML

Fair Value Measurements

9 Months Ended

Sep. 30, 2014

Fair Value Disclosures [Abstract]

Fair Value Measurements

7. Fair Value Measurements

The Company records certain assets and liabilities at fair value. Fair value is defined as the price that would be received to sell an asset or paid to transfer a liability in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants at the measurement date. A three-level fair value hierarchy that prioritizes the inputs used to measure fair value is described below. This hierarchy requires entities to maximize the use of observable inputs and minimize the use of unobservable inputs. The three levels of inputs used to measure fair value are as follows:

• Level 1 — Quoted prices in active markets for identical assets or liabilities.

• Level 2 — Observable inputs other than quoted prices included in Level 1, such as quoted prices for similar assets and liabilities in active markets; quoted prices for identical or similar assets and liabilities in markets that are not active; or other inputs that are observable or can be corroborated by observable market data.

• Level 3 — Unobservable inputs that are supported by little or no market activity. This includes certain pricing models, discounted cash flow methodologies and similar techniques that use significant unobservable inputs.

Recurring Fair Value Measurements

The following table summarizes the fair value of the Company’s financial assets and liabilities that are measured on a recurring basis as of September 30, 2014 (in thousands):

	Level 1		Level 2		Level 3		Total
Assets:
Marketable equity securities	$	1,045	$	—	$	—	$	1,045
Warrants		—		—		13		13
Total	$	1,045	$	—	$	13	$	1,058
Liabilities:
Foreign exchange forward contracts	$	—	$	2,410	$	—	$	2,410
Interest rate swaps		—		17,185		—		17,185
Contingent consideration		—		—		4,443		4,443
Total	$	—	$	19,595	$	4,443	$	24,038

Below is a summary of the valuation techniques used in determining fair value:

Marketable equity securities — The Company values marketable equity securities utilizing quoted market prices.

Foreign exchange forward contracts — The Company values foreign exchange forward contracts using quoted market prices for identical instruments in less active markets or using other observable inputs.

Warrants — The Company values warrants utilizing the Black-Scholes-Merton model.

Interest rate swaps — The Company values interest rate swaps using market inputs with mid-market pricing as a practical expedient for bid-ask spread.

Contingent consideration — The Company values contingent consideration related to business combinations using a weighted probability calculation of potential payment scenarios discounted at rates reflective of the risks associated with the expected future cash flows. Key assumptions used to estimate the fair value of contingent consideration include revenue, net new business and operating forecasts and the probability of achieving the specific targets.

The following table summarizes the changes in Level 3 financial assets and liabilities measured on a recurring basis for the nine months ended September 30 (in thousands):

	Warrants–Deposits and Other Assets				Contingent Consideration – Accounts Payable and Accrued Expenses and Other Liabilities
	2014		2013		2014		2013
Balance as of January 1	$	211	$	29	$	13,014	$	3,521
Initial estimate of contingent consideration		—		—		—		14,300
Revaluations included in earnings		(198)		62		(8,571)		(1,352)
Balance as of September 30	$	13	$	91	$	4,443	$	16,469

The revaluations for the warrants and the contingent consideration are recognized in other (income) expense, net on the accompanying condensed consolidated statements of income.

Non-recurring Fair Value Measurements

Certain assets are carried on the accompanying condensed consolidated balance sheets at cost and are not remeasured to fair value on a recurring basis. These assets include cost and equity method investments and loans that are written down to fair value for declines which are deemed to be other-than-temporary, and goodwill and identifiable intangible assets which are tested for impairment annually and when a triggering event occurs.

As of September 30, 2014, assets carried on the balance sheet and not remeasured to fair value on a recurring basis totaling approximately $824.3 million were identified as Level 3. These assets are comprised of cost and equity method investments of $67.4 million, goodwill of $468.6 million and other identifiable intangibles, net of $288.3 million.

The Company has unfunded cash commitments totaling approximately $27.4 million related to its cost and equity method investments as of September 30, 2014.

Goodwill — Goodwill represents the difference between the purchase price and the fair value of the identifiable tangible and intangible net assets resulting from business combinations. The Company performs a qualitative analysis to determine whether it is more likely than not that the estimated fair value of a reporting unit is less than its book value. This includes a qualitative analysis of macroeconomic conditions, industry and market considerations, internal cost factors, financial performance, fair value history and other company specific events. If this qualitative analysis indicates that it is more likely than not that the estimated fair value is less than the book value for the respective reporting unit, the Company applies a two-step impairment test in which the Company determines whether the estimated fair value of the reporting unit is in excess of its carrying value. If the carrying value of the net assets assigned to the reporting unit exceeds the estimated fair value of the reporting unit, the Company performs the second step of the impairment test to determine the implied estimated fair value of the reporting unit’s goodwill. The Company determines the implied estimated fair value of goodwill by determining the present value of the estimated future cash flows for each reporting unit and comparing the reporting unit’s risk profile and growth prospects to selected, reasonably similar publicly traded companies. No indication of impairment was identified during the Company’s annual review.

Indefinite-lived Intangible Asset — The Company performs a qualitative analysis to determine whether it is more likely than not that the estimated fair value of the indefinite-lived intangible asset is less than its carrying value. If this qualitative analysis indicates that it is more likely than not that the estimated fair value is less than the carrying value of the indefinite-lived intangible asset, the Company determines the estimated fair value of the indefinite-lived intangible asset (trade name) by determining the present value of the estimated royalty payments on an after-tax basis that it would be required to pay the owner for the right to use such trade name. If the carrying amount exceeds the estimated fair value, an impairment loss is recognized in an amount equal to the excess. No indication of impairment was identified during the Company’s annual review.

Other

The estimated fair value of the Company’s long-term debt, which is primarily based on rates in which the debt is traded among banks, was approximately $2.0 billion and $2.1 billion at September 30, 2014 and December 31, 2013, respectively.

XML

Business Combinations

9 Months Ended

Sep. 30, 2014

Business Combinations [Abstract]

Business Combinations

9. Business Combinations

On July 1, 2014, the Company completed the acquisition of Encore Health Resources, LLC (“Encore”) effected through a merger for approximately $91.5 million in cash (net of approximately $2.2 million of acquired cash). Encore has operations in the United States and its business is primarily focused on providing electronic health records (“EHR”) implementation and advisory services to healthcare providers. As part of its Integrated Healthcare Services segment, the Company expects that Encore will enhance its EHR expertise.

This acquisition was a business combination and, accordingly, the assets acquired and the liabilities assumed have been recorded at their respective estimated fair values as of the acquisition date. In connection with the Encore acquisition, the Company recorded goodwill, primarily attributable to the assembled workforce of Encore and expected synergies, which was assigned to the Integrated Healthcare Services segment and is deductible for income tax purposes. The pro forma results of Encore and the acquisition-related expenses are immaterial for separate disclosure. The Company is continuing to evaluate the initial fair value measurement of assets acquired and liabilities assumed as of the acquisition date. Further adjustments may be necessary as additional information related to the fair values of assets acquired and liabilities assumed is assessed during the measurement period (up to one year from the acquisition date). The following table summarizes the preliminary fair value of the net assets acquired of Encore at the date of the acquisition (in thousands):

Assets acquired:

Cash and cash equivalents	$	2,223
Accounts receivable and unbilled services		17,714
Other current assets		443
Property and equipment		289
Goodwill		62,778
Other identifiable intangibles		14,150
Deferred income tax asset – long-term		396
Liabilities assumed:
Accounts payable and accrued expenses		(4,206	)
Other		(31	)
Net assets acquired	$	93,756

The identifiable definite-lived intangible assets consisted of the following:

Other identifiable intangibles (in thousands)
Customer relationships	$	8,800
Acquired backlog		800
Trade names		1,100
Non-compete agreements		450
Software		3,000
Total other identifiable intangibles	$	14,150
Amortized over a weighted average useful life (in years)		8

XML

Earnings Per Share - Summary of Weighted-Average Outstanding Share-Based Awards Excluded from Computation of Diluted Earnings Per Share (Detail) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Earnings Per Share [Abstract]
Weighted average shares subject to anti-dilutive share-based awards	1,324	2,057	1,229	1,635

XML

Earnings Per Share (Tables)

9 Months Ended

Sep. 30, 2014

Earnings Per Share [Abstract]

Summary of Weighted-Average Outstanding Share-Based Awards Excluded from Computation of Diluted Earnings Per Share

The following table shows the weighted average number of outstanding share-based awards not included in the computation of diluted earnings per share as the effect of including such share-based awards in the computation would be anti-dilutive (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
Weighted average shares subject to anti-dilutive share-based awards		1,324		2,057		1,229		1,635

XML

Business Combinations - Summary of Identifiable Definite Lived Intangible Assets (Detail) (USD $) In Thousands, unless otherwise specified	9 Months Ended
	Sep. 30, 2014
Acquired Finite-Lived Intangible Assets [Line Items]
Total other identifiable intangibles	$ 14,150
Amortized over a weighted average useful life (in years)	8 years
Customer Relationships [Member]
Acquired Finite-Lived Intangible Assets [Line Items]
Total other identifiable intangibles	8,800
Acquired Backlog [Member]
Acquired Finite-Lived Intangible Assets [Line Items]
Total other identifiable intangibles	800
Trade Names [Member]
Acquired Finite-Lived Intangible Assets [Line Items]
Total other identifiable intangibles	1,100
Non-compete Agreements [Member]
Acquired Finite-Lived Intangible Assets [Line Items]
Total other identifiable intangibles	450
Software [Member]
Acquired Finite-Lived Intangible Assets [Line Items]
Total other identifiable intangibles	$ 3,000

XML

Segments

9 Months Ended

Sep. 30, 2014

Segment Reporting [Abstract]

Segments

14. Segments

The following table presents the Company’s operations by reportable segment. The Company is managed through two reportable segments, Product Development and Integrated Healthcare Services. Product Development, which primarily serves biopharmaceutical customers engaged in research and development, provides clinical research and clinical trial services. Integrated Healthcare Services provides commercialization services to biopharmaceutical customers and research, analytics, real-world and late phase research, and other services to both biopharmaceutical customers and the broader healthcare market.

Certain costs are not allocated to the Company’s segments and are reported as general corporate and unallocated expenses. These costs primarily consist of share-based compensation and expenses for corporate overhead functions such as finance, human resources, information technology, facilities and legal, as well as certain expenses incurred during the second quarter of 2013, including the $25.0 million fee incurred in connection with the termination of the management agreement with affiliates of certain shareholders and the $1.5 million fee paid in connection with the modification of an agreement for the business usage of an airplane owned by GF Management Company, LLC, a company owned by the Company’s Executive Chairman. The Company does not allocate restructuring or impairment charges to its segments. Information presented below is in thousands:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
Service revenues
Product Development	$	771,361	$	714,244	$	2,323,376	$	2,144,721
Integrated Healthcare Services		289,652		218,483		778,401		659,679
Total service revenues		1,061,013		932,727		3,101,777		2,804,400
Costs of revenue, service costs
Product Development		458,731		426,094		1,374,492		1,296,996
Integrated Healthcare Services		232,320		174,600		634,795		532,473
Total costs of revenue, service costs		691,051		600,694		2,009,287		1,829,469
Selling, general and administrative
Product Development		154,460		147,534		471,697		438,341
Integrated Healthcare Services		37,447		32,221		103,069		96,792
General corporate and unallocated		27,120		19,818		82,517		92,580
Total selling, general and administrative		219,027		199,573		657,283		627,713
Income from operations
Product Development		158,170		140,616		477,187		409,384
Integrated Healthcare Services		19,885		11,662		40,537		30,414
General corporate and unallocated		(27,120)		(19,818)		(82,517)		(92,580)
Restructuring costs		(1,793)		(7,201)		(3,749)		(11,897)
Total income from operations.	$	149,142	$	125,259	$	431,458	$	335,321
	Three Months Ended September 30,				Nine Months Ended September 30,
	2014		2013		2014		2013
Depreciation and amortization expense
Product Development	$	23,106	$	20,853	$	69,867	$	57,901
Integrated Healthcare Services		5,803		5,077		15,548		15,697
General corporate and unallocated		1,271		1,394		3,698		3,352
Total depreciation and amortization expense	$	30,180	$	27,324	$	89,113	$	76,950

XML

Goodwill (Tables)

9 Months Ended

Sep. 30, 2014

Goodwill and Intangible Assets Disclosure [Abstract]

Summary of Goodwill by Segment

The following is a summary of goodwill by segment for the nine months ended September 30, 2014 (in thousands):

	Product Development		Integrated Healthcare Services		Consolidated
Balance as of December 31, 2013	$	351,144	$	58,482	$	409,626
Acquisition		—		62,778		62,778
Impact of foreign currency fluctuations and other		(2,623)		(1,161)		(3,784)
Balance as of September 30, 2014	$	348,521	$	120,099	$	468,620

XML

Business Combinations - Additional Information (Detail) (Encore Health Resources, LLC [Member], USD $) In Millions, unless otherwise specified	9 Months Ended
	Sep. 30, 2014
Encore Health Resources, LLC [Member]
Business Acquisition [Line Items]
Business acquisition through merger	$ 91.5
Date of Acquisition Completed	Jul. 01, 2014
Cash acquired	$ 2.2

XML

Derivatives - Additional Information (Detail) (USD $) In Millions, unless otherwise specified		9 Months Ended				9 Months Ended	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2014 Minimum [Member]	Sep. 30, 2014 Maximum [Member]	Sep. 30, 2014 Interest Rate Swaps [Member]	Jun. 09, 2011 Interest Rate Swaps [Member] Agreement	Sep. 30, 2014 Foreign Exchange Forward Contracts [Member] Derivative	Sep. 30, 2014 Warrants [Member] Warrants	Sep. 30, 2013 Warrants [Member] Warrants	Sep. 30, 2014 Warrants [Member] Warrants	Sep. 30, 2013 Warrants [Member] Warrants
Derivatives And Hedging Activities [Line Items]
Warrant Sold							0	0	0	0
Number of foreign exchange forward contracts					6	12
Notional amount						$ 75.6
Expiration year of hedge instruments						2014
Interest rate swaps expiry date		Sep. 30, 2013	Mar. 31, 2016
Interest Rate Cash Flow Hedge Loss to be Reclassified During Next 12 Months, Net	12.2
Derivative fixed interest rate	2.57%
Interest rate swaps hedged amount due to future change in interest rate swaps				$ 910.0
Interest rate swaps effectively converted percent	44.30%

XML

CONDENSED CONSOLIDATED BALANCE SHEETS (USD $) In Thousands, unless otherwise specified	Sep. 30, 2014	Dec. 31, 2013
Current assets:
Cash and cash equivalents	$ 645,034	$ 778,143
Restricted cash	3,519	2,712
Trade accounts receivable and unbilled services, net	1,032,553	924,205
Prepaid expenses	51,534	42,801
Deferred income taxes	94,175	92,115
Income taxes receivable	17,394	16,171
Other current assets and receivables	94,394	89,541
Total current assets	1,938,603	1,945,688
Property and equipment, net	190,863	199,578
Investments in debt, equity and other securities	33,723	40,349
Investments in and advances to unconsolidated affiliates	34,737	22,927
Goodwill	468,620	409,626
Other identifiable intangibles, net	288,266	298,054
Deferred income taxes	31,278	32,864
Deposits and other assets	120,625	117,711
Total assets	3,106,715	3,066,797
Current liabilities:
Accounts payable and accrued expenses	830,388	861,805
Unearned income	526,000	538,585
Income taxes payable	19,219	35,778
Current portion of long-term debt and obligations held under capital leases	20,681	10,433
Other current liabilities	30,492	35,646
Total current liabilities	1,426,780	1,482,247
Long-term debt and obligations held under capital leases, less current portion	2,022,595	2,035,586
Deferred income taxes	25,578	37,541
Other liabilities	167,994	178,908
Total liabilities	3,642,947	3,734,282
Commitments and contingencies
Shareholders' deficit:
Common stock and additional paid-in capital, 300,000 shares authorized, $0.01 par value, 127,696 and 129,652 shares issued and outstanding at September 30, 2014 and December 31, 2013, respectively	368,010	478,144
Accumulated deficit	(877,224)	(1,145,181)
Accumulated other comprehensive loss	(27,045)	(376)
Deficit attributable to Quintiles Transnational Holdings Inc.'s shareholders	(536,259)	(667,413)
Deficit attributable to noncontrolling interests	27	(72)
Total shareholders' deficit	(536,232)	(667,485)
Total liabilities and shareholders' deficit	$ 3,106,715	$ 3,066,797

XML

Concentration of Credit Risk

9 Months Ended

Sep. 30, 2014

Risks and Uncertainties [Abstract]

Concentration of Credit Risk

3. Concentration of Credit Risk

No customer accounted for 10% or more of consolidated service revenues for the three and nine months ended September 30, 2014 or 2013.

XML

Comprehensive Income - Summary of Components of AOCI (Detail) (USD $) In Thousands, unless otherwise specified	9 Months Ended
	Sep. 30, 2014
Accumulated Other Comprehensive Income (Loss) [Line Items]
Beginning Balance	$ (376)
Other comprehensive (loss) income before reclassifications	(25,895)
Reclassification adjustments	(774)
Ending Balance	(27,045)
Foreign Currency Translation [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Beginning Balance	(5,829)
Other comprehensive (loss) income before reclassifications	(24,523)
Reclassification adjustments
Ending Balance	(30,352)
Marketable Securities [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Beginning Balance	5,708
Other comprehensive (loss) income before reclassifications	(763)
Reclassification adjustments	(5,004)
Ending Balance	(59)
Derivative Instruments [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Beginning Balance	(20,855)
Other comprehensive (loss) income before reclassifications	(3,301)
Reclassification adjustments	4,561
Ending Balance	(19,595)
Defined Benefit Plans [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Beginning Balance	(5,044)
Other comprehensive (loss) income before reclassifications
Reclassification adjustments	572
Ending Balance	(4,472)
Income Taxes [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Beginning Balance	25,644
Other comprehensive (loss) income before reclassifications	2,692
Reclassification adjustments	(903)
Ending Balance	$ 27,433

XML

Derivatives (Tables)

9 Months Ended

Sep. 30, 2014

Summary of Fair Values of Derivative Instruments Designated as Hedges

The fair values of the Company’s derivative instruments designated as hedging instruments and the line items on the accompanying condensed consolidated balance sheets to which they were recorded are summarized in the following table (in thousands):

	Balance Sheet Classification	September 30, 2014		December 31, 2013
Foreign exchange forward contracts	Other current assets	$	—	$	3,950
Foreign exchange forward contracts	Other current liabilities	$	2,410	$	—
Interest rate swaps	Other current liabilities	$	17,185	$	24,805

Effect of Cash Flow Hedging Instruments on Other Comprehensive Income (Loss)

The effect of the Company’s cash flow hedging instruments on other comprehensive income (loss) is summarized in the following table (in thousands):

	Three Months Ended September 30,					Nine Months Ended September 30,
	2014			2013		2014			2013
Foreign exchange forward contracts	$	(5,216	)	$	4,273	$	(6,360	)	$	2,648
Interest rate swaps		3,308			1,381		7,620			6,838
Total	$	(1,908	)	$	5,654	$	1,260		$	9,486

Deposits and other assets [Member]

Summary of Details Relating to Fair Value / Losses (Gains) of Derivative Instruments not Designated as Hedges

The fair values of the Company’s derivative instruments not designated as hedging instruments and the line items on the accompanying condensed consolidated balance sheets to which they were recorded are summarized in the following table (in thousands):

	Balance Sheet Classification	September 30, 2014	December 31, 2013
Warrants	Deposits and other assets	$              13	$              211

XML

Concentration of Credit Risk - Additional Information (Detail) (Sales Revenue [Member])	3 Months Ended		9 Months Ended
	Sep. 30, 2014 Customer	Sep. 30, 2013 Customer	Sep. 30, 2014 Customer	Sep. 30, 2013 Customer
Sales Revenue [Member]
Concentration Risk [Line Items]
Number of customers served	0	0	0	0
Percentage of service revenue from major customers	10.00%	10.00%	10.00%	10.00%

XML

Comprehensive Income

9 Months Ended

Sep. 30, 2014

Equity [Abstract]

Comprehensive Income

13. Comprehensive Income

Below is a summary of the components of AOCI (in thousands):

	Foreign Currency Translation		Marketable Securities		Derivative Instruments		Defined Benefit Plans		Income Taxes		AOCI
Balance at December 31, 2013	$	(5,829)	$	5,708	$	(20,855)	$	(5,044)	$	25,644	$	(376)
Other comprehensive (loss) income before reclassifications		(24,523)		(763)		(3,301)		—		2,692		(25,895)
Reclassification adjustments		—		(5,004)		4,561		572		(903)		(774)
Balance at September 30, 2014	$	(30,352)	$	(59)	$	(19,595)	$	(4,472)	$	27,433	$	(27,045)

Below is a summary of the (gains) losses reclassified from AOCI into the condensed consolidated statements of income and the affected financial statement line item (in thousands):

Reclassification Adjustments	Affected Financial Statement Line Item	Three Months Ended September 30,				Nine Months Ended September 30,
		2014		2013		2014		2013
Marketable securities:
Marketable securities	Other (income) expense, net	$	—	$	—	$	(5,004)	$	—
Total before income taxes			—		—		(5,004)		—
Income tax expense			—		—		(1,927)		—
Total net of income taxes		$	—	$	—	$	(3,077)	$	—
Derivative instruments:
Interest rate swaps	Interest expense	$	3,149	$	3,248	$	9,344	$	9,433
Foreign exchange forward contracts	Service revenues		(614)		121		(4,783)		1,442
Total before income taxes			2,535		3,369		4,561		10,875
Income tax benefit			1,086		1,285		2,616		3,973
Total net of income taxes		$	1,449	$	2,084	$	1,945	$	6,902
Defined benefit plans:
Amortization of prior service costs	See Note 11	$	20	$	83	$	60	$	255
Amortization of actuarial losses	See Note 11		167		169		512		513
Total before income taxes			187		252		572		768
Income tax benefit			70		95		214		290
Total net of income taxes		$	117	$	157	$	358	$	478