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Stock-Based Compensation (Tables)
3 Months Ended
Mar. 31, 2024
Stock-Based Compensation [Abstract]  
Stock-Based Compensation Expense

The following table summarizes the components of stock-based compensation expense in the condensed consolidated statements of operations and comprehensive loss for the three months ended March 31, 2024 and 2023:


    Three Months Ended March 31,
 
   
2024
   
2023
 
    (unaudited)
 

           
Research and development
  $
551,918
    $
800,764
 
General and administrative
   
1,078,093
     
1,279,555
 
Total
  $
1,630,011
    $
2,080,319
 
Assumptions Used to Value Stock Options Granted The fair value of options granted during the three months ended March 31, 2024 and 2023 was estimated using the Black-Scholes option valuation model utilizing the following assumptions:

   
Three Months Ended March 31,
 
   
2024
   
2023
 
   
Weighted Average
   
Weighted Average
 
   
(unaudited)
 
Volatility
   
145.41
%
   
142.02
%
Risk-Free Interest Rate
   
3.98
%
   
4.06
%
Expected Term in Years
   
6.08
     
6.08
 
Dividend Rate            
Fair Value of Option on Grant Date
 
$
5.22
   
$
10.79
 
Stock Option Activity

The following table summarizes the number of options outstanding and the weighted average exercise price:

   
Number
of Shares
   
Weighted
Average
Exercise Price
   
Weighted Average
Remaining
Contractual
Life in Years
   
Aggregate
Intrinsic Value
 
Options outstanding at December 31, 2023
   
5,029,345
   
$
6.43
     
7.42
   
$
4,395,227
 
Granted
   
938,648
     
5.58
      9.90        
Exercised
   
(156,073
)
   
3.40
                 
Forfeited and expired
   
(497,259
)
   
8.64
                 
Options outstanding at March 31, 2024
   
5,314,661
   
$
6.16
     
7.60
   
$
2,327,199
 
Vested and expected to vest at March 31, 2024
   
5,314,661
   
$
6.16
     
7.60
   
$
2,327,199
 
Exercisable at March 31, 2024
   
2,858,485
   
$
5.80
     
6.42
   
$
1,971,346