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Stock-Based Compensation, Assumptions Used to Value Stock Options and Warrants Granted (Details) - $ / shares
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Assumptions Used in Determining Fair Value of Stock Options and Warrants Granted [Abstract]    
Volatility 99.13% 100.38%
Risk-free interest rate 1.10% 0.35%
Expected term 6 years 7 months 20 days 5 years 9 months 25 days
Dividend rate 0.00% 0.00%
Fair value of option on grant date (in dollars per share) $ 4.88 $ 1.73