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Stock-Based Compensation and Warrants - Summary of Activity Under Stock Incentive Plans (Detail) - USD ($)
$ / shares in Units, $ in Thousands
6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Dec. 31, 2019
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]      
Shares Subject to Outstanding, Beginning Balance 661,701    
Shares Subject to Outstanding, Options granted 430,468 184,071  
Shares Subject to Outstanding, Options Forfeited (59,624)    
Shares Subject to Outstanding, Options Expired (35,930)    
Shares Subject to Outstanding, Ending Balance 996,615    
Shares Subject to Outstanding, Vested and expected to vest 980,424    
Shares Subject to Outstanding, Exercisable 508,518    
Weighted-Average Exercise Price Per Share, Outstanding Beginning Balance $ 21.60    
Weighted-Average Exercise Price Per Share, Options granted 4.45    
Weighted-Average Exercise Price Per Share, Options forfeited 5.35    
Weighted-Average Exercise Price Per Share, Options expired 52.51    
Weighted Average Exercise Price Per Share, Outstanding Ending Balance 14.05    
Weighted Average Exercise Price Per Share, Vested and expected to vest 14.19    
Weighted Average Exercise Price Per Share, Exercisable $ 22.18    
Aggregate Intrinsic Value, Outstanding Balance $ 39   $ 305
Aggregate Intrinsic Value, Vested and expected to vest 37    
Aggregate Intrinsic Value, Exercisable $ 2