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Description of Business - Additional Information (Detail)
$ in Thousands
12 Months Ended
Dec. 31, 2018
USD ($)
shares
Dec. 31, 2017
USD ($)
shares
Dec. 31, 2016
USD ($)
Organization Consolidation And Presentation Of Financial Statements [Abstract]      
Place of incorporation Arizona    
Year of incorporation 2002    
Place of reincorporation Delaware    
Date of reincorporation 2015-03    
Reverse split of issued and outstanding common stock 1:20    
Stock split conversion ratio 0.05    
Common stock, authorized | shares 150,000,000 150,000,000  
Accumulated deficit $ 178,366 $ 167,257  
Cash and cash equivalents 11,998 9,125 $ 2,013
Short-term investments 9,825 3,898  
Net losses (13,480) (15,707)  
Net cash used in operations $ (13,631) $ (13,965)