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Property and Equipment, Net - Summary of Property and Equipment, Net (Detail) - USD ($)
$ in Thousands
Dec. 31, 2017
Dec. 31, 2016
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 5,180 $ 5,449
Less accumulated depreciation and amortization (4,881) (4,941)
Property and equipment, net 299 508
Laboratory equipment [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 2,404 2,632
Software and computer equipment [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 424 449
Furniture and fixtures [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 147 153
Vehicles [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 203 204
Leasehold improvements [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 2,002 1,991
Assets under construction [Member]    
Property Plant And Equipment [Line Items]    
Property and equipment, gross   $ 20