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Stock-Based Compensation and Employee Stock Purchase Program - Weighted-Average Fair Value Assumption of Stock Option Awards (Detail) - Employee Stock Option [Member]
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term (years) 6 years 4 months 24 days 6 years 3 months 21 days
Expected volatility 122.00% 121.00%
Risk-free interest rate 2.61% 0.86%
Expected dividend yield 0.00% 0.00%