Segment Information (Tables)

9 Months Ended

Sep. 30, 2022

Segment Information

Schedule of information about reportable segments

The following table presents information about our reportable segments for the three months ended September 30, 2022 and 2021 (in thousands):

	Three months ended September 30,
	2022						2021
	US		Ex-US		Total		US		Ex-US		Total
Product revenue	$	23,019	$	7,644	$	30,663	$	28,699	$	9,217	$	37,916
Operating expenses:
Cost of sales - product		4,487		2,778		7,265		5,488		3,018		8,506
Cost of sales - intangible asset amortization		620		723		1,343		620		723		1,343
Research and development		29,122		1,665		30,787		44,309		1,913		46,222
Selling, general and administrative		25,872		4,508		30,380		26,685		5,511		32,196
Acquired in-process research and development		—		—		—		3,272		—		3,272
Other operating expenses		5,123		—		5,123		3,841		—		3,841
Total expenses		65,224		9,674		74,898		84,215		11,165		95,380
Operating loss	$	(42,205)	$	(2,030)		(44,235)	$	(55,516)	$	(1,948)		(57,464)
Other income (expense):
Interest expense						(9,863)						(8,786)
Foreign currency loss						(2,073)						(1,248)
Other income						192						101
Other income (expense), net						(11,744)						(9,933)
Loss before income taxes						(55,979)						(67,397)
Income tax benefit (expense)						(35)						(13)
Net loss					$	(56,014)					$	(67,410)

	Nine months ended September 30,
	2022						2021
	US		Ex-US		Total		US		Ex-US		Total
Product revenue	$	70,262	$	26,790	$	97,052	$	88,080	$	24,709	$	112,789
Operating expenses:
Cost of sales - product		13,782		9,425		23,207		17,047		8,021		25,068
Cost of sales - intangible asset amortization		1,861		2,168		4,029		1,860		2,168		4,028
Research and development		103,996		5,467		109,463		138,913		5,873		144,786
Selling, general and administrative		76,365		15,818		92,183		77,357		17,698		95,055
Acquired in-process research and development		—		—		—		5,477		—		5,477
Other operating expenses		22,146		—		22,146		11,431		—		11,431
Total expenses		218,150		32,878		251,028		252,085		33,760		285,845
Operating loss	$	(147,888)	$	(6,088)		(153,976)	$	(164,005)	$	(9,051)		(173,056)
Other income (expense):
Interest expense						(28,637)						(25,593)
Foreign currency loss						(5,540)						(2,001)
Other income						511						392
Other income (expense), net						(33,666)						(27,202)
Loss before income taxes						(187,642)						(200,258)
Income tax benefit						127						125
Net loss					$	(187,515)					$	(200,133)