The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACHILLION PHARMACEUTICALS IN | COM | 00448Q201 | 18,210 | 3,000,000 | SH | OTR | 3,000,000 | 0 | 0 | ||
| AKERO THERAPEUTICS INC | COM | 00973Y108 | 10,709 | 482,495 | SH | OTR | 482,495 | 0 | 0 | ||
| ALLAKOS INC | COM | 01671P100 | 64,368 | 675,000 | SH | OTR | 675,000 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 22,646 | 2,325,000 | SH | OTR | 2,325,000 | 0 | 0 | ||
| ANAPTYSBIO INC | COM | 032724106 | 21,125 | 1,300,000 | SH | OTR | 1,300,000 | 0 | 0 | ||
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 | 24,496 | 800,000 | SH | OTR | 800,000 | 0 | 0 | ||
| ARCUS BIOSCIENCES INC | COM | 03969F109 | 16,890 | 1,672,233 | SH | OTR | 1,672,233 | 0 | 0 | ||
| ARGENX SE | SPONSORED ADR | 04016X101 | 32,104 | 200,000 | SH | OTR | 200,000 | 0 | 0 | ||
| ARVINAS INC | COM | 04335A105 | 15,039 | 366,000 | SH | OTR | 366,000 | 0 | 0 | ||
| ATRECA INC | CL A COM | 04965G109 | 26,819 | 1,733,583 | SH | OTR | 1,733,583 | 0 | 0 | ||
| BARCLAYS BK PLC | IPATH B SHRT TRM | 06746P621 | 15,120 | 1,000,000 | SH | OTR | 1,000,000 | 0 | 0 | ||
| BEIGENE LTD | SPONSORED ADR | 07725L102 | 153,328 | 925,000 | SH | OTR | 925,000 | 0 | 0 | ||
| BELLUS HEALTH INC NEW | COM NEW | 07987C204 | 13,490 | 1,775,000 | SH | OTR | 1,775,000 | 0 | 0 | ||
| BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 21,138 | 250,000 | SH | OTR | 250,000 | 0 | 0 | ||
| CABALETTA BIO INC | COM | 12674W109 | 21,882 | 1,566,361 | SH | OTR | 1,566,361 | 0 | 0 | ||
| CELLECTAR BIOSCIENCES INC | COM PAR | 15117F500 | 2,070 | 920,000 | SH | OTR | 920,000 | 0 | 0 | ||
| CYMABAY THERAPEUTICS INC | COM | 23257D103 | 3,920 | 2,000,000 | SH | OTR | 2,000,000 | 0 | 0 | ||
| DBV TECHNOLOGIES S A | SPONSORED ADR | 23306J101 | 68,315 | 6,384,598 | SH | OTR | 6,384,598 | 0 | 0 | ||
| DIREXION SHS ETF TR | DAILY S&P BIOTEC | 25460E539 | 35,630 | 2,885,000 | SH | OTR | 2,885,000 | 0 | 0 | ||
| ESPERION THERAPEUTICS INC NE | COM | 29664W105 | 58,139 | 975,000 | SH | OTR | 975,000 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 19,873 | 250,000 | SH | OTR | 250,000 | 0 | 0 | ||
| GOSSAMER BIO INC | COM | 38341P102 | 34,152 | 2,185,000 | SH | OTR | 2,185,000 | 0 | 0 | ||
| IDEAYA BIOSCIENCES INC | COM | 45166A102 | 5,732 | 764,252 | SH | OTR | 764,252 | 0 | 0 | ||
| IMMUNOMEDICS INC | COM | 452907108 | 178,802 | 8,450,000 | SH | OTR | 8,450,000 | 0 | 0 | ||
| KADMON HLDGS INC | COM | 48283N106 | 28,113 | 6,205,882 | SH | OTR | 6,205,882 | 0 | 0 | ||
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 | 3,562 | 200,000 | SH | OTR | 200,000 | 0 | 0 | ||
| KINIKSA PHARMACEUTICALS LTD | COM CL A | G5269C101 | 3,214 | 290,577 | SH | OTR | 290,577 | 0 | 0 | ||
| KURA ONCOLOGY INC | COM | 50127T109 | 11,616 | 844,789 | SH | OTR | 844,789 | 0 | 0 | ||
| LA JOLLA PHARMACEUTICAL CO | COM PAR $.0001 2 | 503459604 | 3,046 | 775,000 | SH | OTR | 775,000 | 0 | 0 | ||
| LEXICON PHARMACEUTICALS INC | COM NEW | 528872302 | 11,516 | 2,775,000 | SH | OTR | 2,775,000 | 0 | 0 | ||
| MARINUS PHARMACEUTICALS INC | COM | 56854Q101 | 10,368 | 4,800,000 | SH | OTR | 4,800,000 | 0 | 0 | ||
| MATINAS BIOPHARMA HLDGS INC | COM | 576810105 | 23,127 | 10,188,312 | SH | OTR | 10,188,312 | 0 | 0 | ||
| MEDICINES CO | COM | 584688105 | 82,137 | 967,000 | SH | OTR | 967,000 | 0 | 0 | ||
| MEDICINES CO | CALL | 584688905 | 8,494 | 100,000 | SH | Call | OTR | 100,000 | 0 | 0 | |
| MEI PHARMA INC | COM NEW | 55279B202 | 7,224 | 2,913,091 | SH | OTR | 2,913,091 | 0 | 0 | ||
| MILESTONE PHARMACEUTICALS IN | COM | 59935V107 | 17,646 | 1,102,194 | SH | OTR | 1,102,194 | 0 | 0 | ||
| MIRATI THERAPEUTICS INC | COM | 60468T105 | 221,067 | 1,715,560 | SH | OTR | 1,715,560 | 0 | 0 | ||
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | 7,773 | 317,000 | SH | OTR | 317,000 | 0 | 0 | ||
| NEOLEUKIN THERAPEUTICS INC | COM | 64049K104 | 12,434 | 1,009,255 | SH | OTR | 1,009,255 | 0 | 0 | ||
| ODONATE THERAPEUTICS INC | COM | 676079106 | 109,142 | 3,363,377 | SH | OTR | 3,363,377 | 0 | 0 | ||
| PREVAIL THERAPEUTICS INC | COM | 74140Y101 | 17,779 | 1,123,105 | SH | OTR | 1,123,105 | 0 | 0 | ||
| RELMADA THERAPEUTICS INC | COM | 75955J402 | 11,700 | 300,000 | SH | OTR | 300,000 | 0 | 0 | ||
| ROCKET PHARMACEUTICALS INC | COM | 77313F106 | 33,367 | 1,466,051 | SH | OTR | 1,466,051 | 0 | 0 | ||
| SAGE THERAPEUTICS INC | COM | 78667J108 | 25,267 | 350,000 | SH | OTR | 350,000 | 0 | 0 | ||
| SAREPTA THERAPEUTICS INC | COM | 803607100 | 29,034 | 225,000 | SH | OTR | 225,000 | 0 | 0 | ||
| SEATTLE GENETICS INC | COM | 812578102 | 57,130 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| SELECTA BIOSCIENCES INC | COM | 816212104 | 7,816 | 3,284,072 | SH | OTR | 3,284,072 | 0 | 0 | ||
| SOLID BIOSCIENCES INC | COM | 83422E105 | 4,592 | 1,031,872 | SH | OTR | 1,031,872 | 0 | 0 | ||
| SPRINGWORKS THERAPEUTICS INC | COM | 85205L107 | 79,902 | 2,075,905 | SH | OTR | 2,075,905 | 0 | 0 | ||
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 2,195 | 250,000 | SH | OTR | 250,000 | 0 | 0 | ||
| UNIQURE NV | SHS | N90064101 | 54,849 | 765,400 | SH | OTR | 765,400 | 0 | 0 | ||