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Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Statement Of Income And Comprehensive Income [Abstract]      
Licensing revenue – Related Party $ 4,784 $ 0 $ 0
Operating expenses:      
Research and development 38,393 67,309 70,957
General and administrative 23,056 24,025 20,046
Change in fair value of contingent consideration 0 (33) (1,352)
Impairment of long-lived assets 0 2,629 0
Total operating expenses 61,449 93,930 89,651
Loss from operations (56,665) (93,930) (89,651)
Interest income 100 1,196 3,289
Interest expense (3,177) (1,292) 0
Other (expense) income, net (983) 182 4,185
Net loss (60,725) (93,844) (82,177)
Other comprehensive loss      
Unrealized (loss) gain on marketable debt securities (49) (85) 185
Comprehensive loss $ (60,774) $ (93,929) $ (81,992)
Net loss per share, basic and diluted $ (1.09) $ (1.84) $ (1.88)
Weighted average number of shares used in computing net loss per share, basic and diluted 55,815,873 50,864,889 43,624,807