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Balance Sheet Components
12 Months Ended
Dec. 31, 2021
Balance Sheet Related Disclosures [Abstract]  
Balance Sheet Components

6. Balance Sheet Components

Property and Equipment, Net

Property and equipment, net, consists of the following (in thousands):

 

 

 

December 31,

 

 

 

2021

 

 

2020

 

Laboratory equipment

 

$

5,718

 

 

$

5,960

 

Computer equipment

 

 

499

 

 

 

501

 

Furniture and fixtures

 

 

818

 

 

 

825

 

Leasehold improvements

 

 

15,158

 

 

 

15,083

 

Total property and equipment

 

 

22,193

 

 

 

22,369

 

Less: accumulated depreciation and amortization

 

 

(12,258

)

 

 

(9,742

)

Construction-in-progress

 

 

7

 

 

 

 

Total property and equipment, net

 

$

9,942

 

 

$

12,627

 

 

Depreciation and amortization expense related to property and equipment was $2.9 million, $3.4 million and $2.7 million for the years ended December 31, 2021, 2020 and 2019, respectively.

Accrued and Other Current Liabilities

Accrued and other current liabilities consist of the following (in thousands):

 

 

 

December 31,

 

 

 

2021

 

 

2020

 

Operating lease liability - current portion

 

$

4,378

 

 

$

4,520

 

Accrued research and development

 

 

1,390

 

 

 

1,638

 

Liability related to early exercise shares

 

 

10

 

 

 

21

 

Accrued other

 

 

592

 

 

 

371

 

 

 

$

6,370

 

 

$

6,550