Income Taxes (Tables)

12 Months Ended

Dec. 31, 2022

Income Tax Disclosure [Abstract]

Schedule of Components of Loss Before Income Taxes

The components of the Company’s loss before income taxes are as follows:

	Year Ended December 31,
	2022		2021
	(in thousands)
Domestic	$	(61,396)	$	(57,035)
Foreign	140		463
Loss before income taxes	$	(61,256)	$	(56,572)

Schedule of Components of Income Tax Expense

The components of deferred income taxes are as follows:

	Year Ended December 31,
	2022		2021
	(in thousands)
Federal	$	13,085	$	12,994
State	2,997		1,878
Foreign	(92)		461
Total deferred income taxes	15,990		15,333
Change in deferred tax valuation allowance	(15,990)		(15,333)
Net deferred income tax	$	—	$	—

Schedule of Effective Income Tax Rate Reconciliation

Income tax expense differs from the amount computed by applying the statutory federal income tax rate due to the following:

	Year Ended December 31,
	2022		2021
Tax at statutory federal rate	(21.0)	%	(21.0)	%
State tax, net of federal benefit	(4.9)	%	(3.3)	%
Tax credits	(0.7)	%	(0.8)	%
Change in deferred tax valuation allowance	26.1	%	27.1	%
Stock compensation	0.3	%	(1.7)	%
Foreign rate differences	0.1	%	0.1	%
Other	0.1	%	(0.4)	%
Total income tax expense	—	%	—	%

Schedule of Deferred Tax Assets

The tax effects of temporary differences and carryforwards that give rise to significant portions of the deferred tax assets are presented below:

	Year Ended December 31,
	2022		2021
	(in thousands)
Net operating loss carryforwards	$	77,057	$	66,015
Research and development credits	4,464		3,837
Accruals and reserves	2,616		1,994
Interest limitation	4,447		3,995
Depreciation and amortization	263		152
Stock compensation	3,378		2,728
Operating lease liabilities	1,079		1,376
Capitalized research and development	2,486		—
Total deferred tax assets	95,790		80,097
Operating lease right-of-use assets	(1,014)		(1,311)
Total deferred tax liabilities	(1,014)		(1,311)
Less: Valuation allowance	(94,776)		(78,786)
Total deferred tax asset, net of valuation allowance	$	—	$	—

Summary of Changes in Valuation Allowance

The following table summarizes changes in the valuation allowance for the years ended December 31, 2022 and 2021:

	Year Ended December 31,
	2022		2021
	(in thousands)
Beginning balance	$	78,786	$	63,453
Net changes during the period	15,990		15,333
Ending balance	$	94,776	$	78,786

Schedule of Uncertain Income Tax Positions

The changes in the Company’s uncertain income tax positions for the years ended December 31, 2022 and 2021 consisted of the following:

	Year ended December 31,
	2022		2021
	(in thousands)
Balance at beginning of the year	$	2,655	$	1,513
Increases related to tax positions taken prior to current year	(12)		$	817
Increases related to current year's tax positions	301		325
Balance at end of the year	$	2,944	$	2,655